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Paper · 374246

The differentiation of murine thymocytes in vivo and in vitro.

Mandel TE and 1 other. Immunology, 1978. Cited by 118 papers, by iCite.

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ConductScience Library. The differentiation of murine thymocytes in vivo and in vitro. Papers, record 374246. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/374246

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The differentiation of murine thymocytes in vivo and in vitro.
PubMed
Journal
Immunology
PubMed
Year
1978
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
118
iCite
Relative citation ratio, by iCite
2.13
iCite
Revised in PubMed
2018-11-13
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Mandel TET E
2Kennedy MMM M

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
T-LymphocytesMajor topic
Thymus GlandMajor topic
Animals
Antigens, Surface
Cell Count
Cell Differentiation
Fluorescent Antibody Technique
Mice
Mice, Inbred Strains
Organ Culture Techniques
Receptors, Antigen, B-Cell
Time Factors

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References20

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
113,795,076Morphogenetic interactions in the development of the mouse thymus gland.Dev Biol1960https://conductscience.org/library/papers/13795076PubMed
2136,742Role of the thymus in generation of lymphocyte functions. I. Demonstration of lymphocytes reactive to mitogens and allogeneic cells in the embryonic mouse thymus in organ culture.Scand J Immunol1976https://conductscience.org/library/papers/136742PubMed
31,087,581The differentiation of T-lymphocytes. III. The behaviour of subpopulations of mouse thymus cells in short-term cell culture.Cell Immunol1976https://conductscience.org/library/papers/1087581PubMed
44,117,678Antigens of the thymus.Prog Allergy1972https://conductscience.org/library/papers/4117678PubMed
560,778Morphologic and antigenic maturation of lymphocytes in the mouse thymus in vitro.Scand J Immunol1976https://conductscience.org/library/papers/60778PubMed
64,583,069Differentiation of T-cell precursors in nude mice demonstrated by immunofluorescence of T-cell membrane markers.J Exp Med1973https://conductscience.org/library/papers/4583069PubMed
74,580,464Characterization of splenic lymphoid cells in fetal and newborn mice.J Exp Med1973https://conductscience.org/library/papers/4580464PubMed
84,565,838Functional maturation of thymic lymphocyte populations in vitro.J Exp Med1972https://conductscience.org/library/papers/4565838PubMed
94,549,190The differentiation of T lymphocytes. I. Proliferation kinetics and interrelationships of subpopulations of mouse thymus cells.Cell Immunol1974https://conductscience.org/library/papers/4549190PubMed
104,539,848Thymus cell maturation. Studies on the origin of cortisone-resistant thymic lymphocytes.J Exp Med1973https://conductscience.org/library/papers/4539848PubMed

1 to 10 of 20

See all 20 references

Cited by22

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 118 citations.

PMIDTitleJournalYearIn PapersSource
42,111,706Generation of Functional Patient-Specific Thymus Organoids From Human Pluripotent Stem Cells (hPSCs) Using Air-Liquid Interface Culture.Bio Protoc2026https://conductscience.org/library/papers/42111706PubMed
41,693,238The Thymus Regeneration Paradox: The Search for Stemness in an Involuting Organ.Immunol Rev2026https://conductscience.org/library/papers/41693238PubMed
36,963,390Generation of functional thymic organoids from human pluripotent stem cells.Stem Cell Reports2023https://conductscience.org/library/papers/36963390PubMed
33,859,647High-Oxygen Submersion Fetal Thymus Organ Cultures Enable FOXN1-Dependent and -Independent Support of T Lymphopoiesis.Front Immunol2021https://conductscience.org/library/papers/33859647PubMed
28,546,567Thymic homing of activated CD4+ T cells induces degeneration of the thymic epithelium through excessive RANK signaling.Sci Rep2017https://conductscience.org/library/papers/28546567PubMed
7,902,570Human bone marrow and umbilical cord blood cells generate CD4+ and CD8+ single-positive T cells in murine fetal thymus organ culture.Proc Natl Acad Sci U S A1993https://conductscience.org/library/papers/7902570PubMed
6,970,622Thymic microenvironment and cultures derived from mouse thymic explants. A morphological study.Cell Tissue Res1981https://conductscience.org/library/papers/6970622PubMed
6,965,399Ontogenic development of B-lymphocyte function and tolerance susceptibility in vivo and in an in vitro organ culture system.J Exp Med1980https://conductscience.org/library/papers/6965399PubMed
6,607,214Anamnestic responses induced by antigen persisting on follicular dendritic cells from cyclophosphamide-treated mice.Immunology1984https://conductscience.org/library/papers/6607214PubMed
6,602,338Functional clonal deletion of cytotoxic T-lymphocyte precursors in chimeric thymus produced in vitro from embryonic Anlagen.Proc Natl Acad Sci U S A1983https://conductscience.org/library/papers/6602338PubMed

1 to 10 of 22

See all 22 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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