Paper · 37798442
Therapeutic developments in pancreatic cancer.
Hu ZI and 1 other. Nat Rev Gastroenterol Hepatol, 2024. Cited by 375 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Therapeutic developments in pancreatic cancer. Papers, record 37798442. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/37798442
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics5
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Pancreatic Neoplasms | Major topic |
| Carcinoma, Pancreatic Ductal | Major topic |
| Humans | |
| Immunotherapy | |
| Forecasting |
Source PubMed
Grants1
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by |
|---|---|---|---|---|
| P50 CA257881 | NCI NIH HHS | United States | P50CA257881 | PubMed |
Source NIH RePORTER
Trials1
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
| Trial | Title | The trial lists it as | Named in the paper's record |
|---|---|---|---|
| NCT07226154 | Prediction of Neoadjuvant Chemotherapy Response in Pancreatic Cancer | Background |
Source ClinicalTrials.gov
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References191
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 27,275,632 | Preoperative Modified FOLFIRINOX Treatment Followed by Capecitabine-Based Chemoradiation for Borderline Resectable Pancreatic Cancer: Alliance for Clinical Trials in Oncology Trial A021101. | JAMA Surg | 2016 | https://conductscience.org/library/papers/27275632 | PubMed |
| 2 | 31,134,896 | Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer. | Elife | 2019 | https://conductscience.org/library/papers/31134896 | PubMed |
| 3 | 34,644,529 | Spatially confined sub-tumor microenvironments in pancreatic cancer. | Cell | 2021 | https://conductscience.org/library/papers/34644529 | PubMed |
| 4 | 25,678,581 | Induction of T-cell Immunity Overcomes Complete Resistance to PD-1 and CTLA-4 Blockade and Improves Survival in Pancreatic Carcinoma. | Cancer Immunol Res | 2015 | https://conductscience.org/library/papers/25678581 | PubMed |
| 5 | 32,135,080 | Overall survival in patients with pancreatic cancer receiving matched therapies following molecular profiling: a retrospective analysis of the Know Your Tumor registry trial. | Lancet Oncol | 2020 | https://conductscience.org/library/papers/32135080 | PubMed |
| 6 | 32,931,022 | Clinical trial design: Past, present, and future in the context of big data and precision medicine. | Cancer | 2020 | https://conductscience.org/library/papers/32931022 | PubMed |
| 7 | 33,387,490 | CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label, multicentre, phase 1b study. | Lancet Oncol | 2021 | https://conductscience.org/library/papers/33387490 | PubMed |
| 8 | 21,934,105 | An emerging entity: pancreatic adenocarcinoma associated with a known BRCA mutation: clinical descriptors, treatment implications, and future directions. | Oncologist | 2011 | https://conductscience.org/library/papers/21934105 | PubMed |
| 9 | 36,459,568 | Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity. | Cancer Res | 2023 | https://conductscience.org/library/papers/36459568 | PubMed |
| 10 | 8,097,319 | Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. | Proc Natl Acad Sci U S A | 1993 | https://conductscience.org/library/papers/8097319 | PubMed |
1 to 10 of 191
See all 191 referencesCited by277
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 375 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,983,487 | Dual-organelle-coordinated sonodynamic nanoplatform amplifies immunogenic cell death to drive robust antitumor immunity in cold tumors. | J Nanobiotechnology | 2026 | https://conductscience.org/library/papers/42983487 | PubMed |
| 42,952,609 | Disruption of ACTG1 potentiates anti-TIM-3 immunotherapy by reprogramming the immunosuppressive microenvironment via the CSF3/CSF3R axis in pancreatic cancer. | Front Immunol | 2026 | https://conductscience.org/library/papers/42952609 | PubMed |
| 42,934,594 | Burdens of pancreatic cancer from 1990 to 2021 and projection to 2050 in China: findings from the 2021 global burden of disease study. | BMC Cancer | 2026 | https://conductscience.org/library/papers/42934594 | PubMed |
| 42,892,656 | Difluoromethylornithine modulates mutant K-RAS signaling pathways in pancreatic cancer cells. | Amino Acids | 2026 | https://conductscience.org/library/papers/42892656 | PubMed |
| 42,873,463 | Actinomycetota-Derived Metabolites in Pancreatic Cancer: Chemical Diversity, Metabolic Vulnerability, and Translational Barriers. | Curr Oncol Rep | 2026 | https://conductscience.org/library/papers/42873463 | PubMed |
| 42,861,168 | Sialic Acid-Targeting Lectin-Conjugated Oxygen Nanosomes Alleviate Hypoxia and Promote Macrophage Activation in Pancreatic Cancer Cells. | Int J Nanomedicine | 2026 | https://conductscience.org/library/papers/42861168 | PubMed |
| 42,858,298 | MVB Maturation Responsive to KRASG12D/TP53R175H Co-mutations Fuels Extracellular Vesicle-hypersecretion Phenotype to Aggravate Lymphangiogenesis and Lymphatic Metastasis. | J Extracell Vesicles | 2026 | https://conductscience.org/library/papers/42858298 | PubMed |
| 42,856,962 | Super-Resolution MRI-Derived Tumor-Stroma Ratio Phenotyping for Prognostic and Therapeutic Stratification in Pancreatic Ductal Adenocarcinoma. | MedComm (2020) | 2026 | https://conductscience.org/library/papers/42856962 | PubMed |
| 42,844,287 | Deep learning CT signature for predicting early liver metastases in pancreatic ductal adenocarcinoma. | Nat Commun | 2026 | https://conductscience.org/library/papers/42844287 | PubMed |
| 42,797,417 | Contemporary Landscape of Active Clinical Trials in Pancreatic Ductal Adenocarcinoma: A ClinicalTrials.gov-Based Narrative Review with a Scoping Approach. | Pharmaceuticals (Basel) | 2026 | https://conductscience.org/library/papers/42797417 | PubMed |
1 to 10 of 277
See all 277 cited byGenes1
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes |
|---|---|---|---|
| KRAS | 3,845 | PubTator's text mining | https://conductscience.org/library/genes/3845 |
Source NCBI Gene
Drugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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