Paper · 38537635

Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells.

Hu C and 10 others. Cell Metab, 2024. Cited by 25 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells. Papers, record 38537635. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/38537635

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells.; PubMed
Journal: Cell Metab; PubMed
Year: 2024; PubMed
Publication types: Published Erratum; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/38537635/; PubMed
DOI: https://doi.org/10.1016/j.cmet.2024.03.013; PubMed
The journal: https://conductscience.org/library/journal-index/101233170; PubMed
Citations, by iCite: 25; iCite
Relative citation ratio, by iCite: 2.69, provisional; iCite
Revised in PubMed: 2024-05-09; PubMed

Authors11

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Hu C	Cegui
2	Qiao W	Wen
3	Li X	Xiang
4	Ning ZK	Zhi-Kun
5	Liu J	Jiang
6	Dalangood S	Sumiya
7	Li H	Hanjun
8	Yu X	Xiang
9	Zong Z	Zhen
10	Wen Z	Zhenke

1 to 10 of 11Source PubMed

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Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections1

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

Kind	PMID	Title	In Papers
Erratum for	38,309,268	Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells.	https://conductscience.org/library/papers/38309268

Source PubMed

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by18

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 25 citations.

PMID	Title	Journal	Year	In Papers	Source
42,434,120	Antagonism of β-klotho signaling by peptide 19 impairs wheel running in male mice and potentiates the cisplatin-induced decrease in wheel running.	Front Pharmacol	2026	https://conductscience.org/library/papers/42434120	PubMed
41,946,907	Lipid metabolism reprogramming shapes the immune landscape in the tumor microenvironment.	Cell Mol Immunol	2026	https://conductscience.org/library/papers/41946907	PubMed
41,840,707	Targeting cholesterol-driven immunometabolism in cancer: from molecular circuits to clinical translation.	Mol Cancer	2026	https://conductscience.org/library/papers/41840707	PubMed
41,634,890	Fos-induced osteosarcoma growth causes a cachexia-like phenotype in mice and correlates with high Fgf21 serum levels.	Cancer Metab	2026	https://conductscience.org/library/papers/41634890	PubMed
41,542,770	Targeting the N-acetyltransferase 10/DKK2 axis enhances CD8+ T cell antitumor activity in colorectal cancer models.	J Clin Invest	2026	https://conductscience.org/library/papers/41542770	PubMed
41,369,841	Breast Cancer Progression by the FGF/FGFR Axis: A Metabolic Perspective.	J Mammary Gland Biol Neoplasia	2025	https://conductscience.org/library/papers/41369841	PubMed
41,112,263	Single-cell and spatial transcriptomics integration: new frontiers in tumor microenvironment and cellular communication.	Front Immunol	2025	https://conductscience.org/library/papers/41112263	PubMed
41,049,741	Nanomedicine strategies for cuproptosis: Metabolic reprogramming and tumor immunotherapy.	Acta Pharm Sin B	2025	https://conductscience.org/library/papers/41049741	PubMed
40,782,287	Prominent fibroblast growth factor 21 with less abundant tumor-associated macrophages in hepatic mass of the conditional mgmt-deleted mice using LysM-Cre system.	Inflamm Res	2025	https://conductscience.org/library/papers/40782287	PubMed
40,658,684	Bi-directional metabolic reprogramming between cancer cells and T cells reshapes the anti-tumor immune response.	PLoS Biol	2025	https://conductscience.org/library/papers/40658684	PubMed

1 to 10 of 18

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Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
CD8A	925	PubTator's text mining	https://conductscience.org/library/genes/925	NCBI Gene
FGF21	26,291	PubTator's text mining	https://conductscience.org/library/genes/26291	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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