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Paper · 38935528

PLL-g-PEG Polymer Inhibits Antibody-Drug Conjugate Uptake into Human Corneal Epithelial Cells In Vitro.

Kleinman D and 6 others. J Ocul Pharmacol Ther, 2024. Cited by 5 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. PLL-g-PEG Polymer Inhibits Antibody-Drug Conjugate Uptake into Human Corneal Epithelial Cells In Vitro. Papers, record 38935528. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/38935528

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
PLL-g-PEG Polymer Inhibits Antibody-Drug Conjugate Uptake into Human Corneal Epithelial Cells In Vitro.
PubMed
Journal
J Ocul Pharmacol Ther
PubMed
Year
2024
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural
PubMed
Citations, by iCite
5
iCite
Relative citation ratio, by iCite
0.71, provisional
iCite
Revised in PubMed
2026-09-02
PubMed

Authors7

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Kleinman DDavidhttps://orcid.org/0000-0002-1311-5216
2Iqbal SSanahttps://orcid.org/0009-0005-6191-0539
3Ghosh AKAnita K
4Ogle SDSean D
5Kaja SSimonhttps://orcid.org/0000-0001-6878-521X
6Mitchnick MMark
7Hakkarainen JJJenni Jhttps://orcid.org/0000-0002-2528-7525

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
ImmunoconjugatesMajor topic
Polyethylene GlycolsMajor topic
Epithelium, CornealMajor topic
Humans
Polylysine
Cell Proliferation
Epithelial Cells
Oligopeptides
Amiloride
Polymers
Cells, Cultured
Pinocytosis

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
R24 EY032440NEI NIH HHSUnited StatesR24EY032440PubMed and NIH

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References39

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
118,284,809Cell culture models of the human cornea - a comparative evaluation of their usefulness to determine ocular drug absorption in-vitro.J Pharm Pharmacol2008https://conductscience.org/library/papers/18284809PubMed
29,310,469IDEC-C2B8 (Rituximab) anti-CD20 monoclonal antibody therapy in patients with relapsed low-grade non-Hodgkin's lymphoma.Blood1997https://conductscience.org/library/papers/9310469PubMed
330,807,830Manganese(III) tetrakis(1-methyl-4-pyridyl) porphyrin, a superoxide dismutase mimetic, reduces disease severity in in vitro and in vivo models for dry-eye disease.Ocul Surf2019https://conductscience.org/library/papers/30807830PubMed
431,659,006Antibody-Drug Conjugates: A Comprehensive Review.Mol Cancer Res2020https://conductscience.org/library/papers/31659006PubMed
534,218,869Corneal Epitheliopathy Associated With Antibody-Drug Conjugates.Mayo Clin Proc2021https://conductscience.org/library/papers/34218869PubMed
629,382,707Modulation of Macropinocytosis-Mediated Internalization Decreases Ocular Toxicity of Antibody-Drug Conjugates.Cancer Res2018https://conductscience.org/library/papers/29382707PubMed
726,539,624Ocular Adverse Events Associated with Antibody-Drug Conjugates in Human Clinical Trials.J Ocul Pharmacol Ther2015https://conductscience.org/library/papers/26539624PubMed
827,045,800Effects of antibody, drug and linker on the preclinical and clinical toxicities of antibody-drug conjugates.MAbs2016https://conductscience.org/library/papers/27045800PubMed
99,740,007Reduction of fibrous adhesion formation by a copolymer possessing an affinity for anionic surfaces.J Biomed Mater Res1998https://conductscience.org/library/papers/9740007PubMed
1030,413,525Evaluation of Prophylactic Corticosteroid Eye Drop Use in the Management of Corneal Abnormalities Induced by the Antibody-Drug Conjugate Mirvetuximab Soravtansine.Clin Cancer Res2019https://conductscience.org/library/papers/30413525PubMed

Cited by5

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 5 citations.

PMIDTitleJournalYearIn PapersSource
42,792,744MSC EVs Deliver miRNAs into Cardiomyocytes via EIPA-Sensitive and Clathrin-Mediated Endocytosis.Biomedicines2026https://conductscience.org/library/papers/42792744PubMed
42,563,409Ocular Tissue Distribution of Ocular Surface Immunoglobulin Following Topical and Subconjunctival Administration: A Novel Strategy for Mitigation of Antibody-Drug Conjugate-Associated Ocular Toxicity.J Ocul Pharmacol Ther2026https://conductscience.org/library/papers/42563409PubMed
42,079,870Antibody-drug conjugates for infectious and neglected tropical diseases: chemical design principles, target biology, and translational challenges.Front Chem2026https://conductscience.org/library/papers/42079870PubMed
41,707,651Syndecan-1-targeted therapeutic antibody impairs macropinocytosis and elicits antitumor immunity in pancreatic cancer.Cell Rep Med2026https://conductscience.org/library/papers/41707651PubMed
41,540,298Bench-to-Bedside Perspectives on Ocular Toxicity of Antibody-Drug Conjugates: Toxicology, Clinical Management and Molecule Optimization.Pharm Res2026https://conductscience.org/library/papers/41540298PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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