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Paper · 39052000

A syngeneic spontaneous zebrafish model of tp53-deficient, EGFRvIII, and PI3KCAH1047R-driven glioblastoma reveals inhibitory roles for inflammation during tumor initiation and relapse in vivo.

Weiss A and 3 others. Elife, 2024. Cited by 10 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. A syngeneic spontaneous zebrafish model of tp53-deficient, EGFRvIII, and PI3KCAH1047R-driven glioblastoma reveals inhibitory roles for inflammation during tumor initiation and relapse in vivo. Papers, record 39052000. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/39052000

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
A syngeneic spontaneous zebrafish model of tp53-deficient, EGFRvIII, and PI3KCAH1047R-driven glioblastoma reveals inhibitory roles for inflammation during tumor initiation and relapse in vivo.
PubMed
Journal
Elife
PubMed
Year
2024
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
10
iCite
Relative citation ratio, by iCite
1.27, provisional
iCite
Revised in PubMed
2024-07-31
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Weiss AAlex
2D'Amata CCassandra
3Pearson BJBret Jhttps://orcid.org/0000-0002-3473-901X
4Hayes MNMadeline Nhttps://orcid.org/0000-0002-0089-8995

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
ZebrafishMajor topic
GlioblastomaMajor topic
Disease Models, AnimalMajor topic
Tumor Suppressor Protein p53Major topic
ErbB ReceptorsMajor topic
Zebrafish ProteinsMajor topic
InflammationMajor topic
Brain NeoplasmsMajor topic
Animals
Humans
Tumor Microenvironment

Source PubMed

Grants7

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
FellowshipCIHRCanadaPubMedPubMed
PJT-159611CIHRCanadaPubMedPubMed
IA-026Ontario Institute for Cancer ResearchPubMedPubMed
R01 GM155244NIGMS NIH HHSUnited StatesR01GM155244PubMed and NIHNIH RePORTER
Start-up FundsHospital for Sick ChildrenPubMedPubMed
1R01GM155244NIH HHSUnited StatesR01GM155244PubMed and NIHNIH RePORTER
Start-up FundsOregon Health and Science UniversityPubMedPubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References84

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
132,641,768Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy.Nat Commun2020https://conductscience.org/library/papers/32641768PubMed
223,347,562Wnt signaling in stem and cancer stem cells.Curr Opin Cell Biol2013https://conductscience.org/library/papers/23347562PubMed
331,697,921Microglia/Brain Macrophages as Central Drivers of Brain Tumor Pathobiology.Neuron2019https://conductscience.org/library/papers/31697921PubMed
429,117,289CBTRUS Statistical Report: Primary brain and other central nervous system tumors diagnosed in the United States in 2010-2014.Neuro Oncol2017https://conductscience.org/library/papers/29117289PubMed
521,775,966Quantifying the frequency of tumor-propagating cells using limiting dilution cell transplantation in syngeneic zebrafish.J Vis Exp2011https://conductscience.org/library/papers/21775966PubMed
627,631,880A Tol2 Gateway-Compatible Toolbox for the Study of the Nervous System and Neurodegenerative Disease.Zebrafish2017https://conductscience.org/library/papers/27631880PubMed
734,466,804Mouse models of glioblastoma for the evaluation of novel therapeutic strategies.Neurooncol Adv2021https://conductscience.org/library/papers/34466804PubMed
828,609,654Intertumoral Heterogeneity within Medulloblastoma Subgroups.Cancer Cell2017https://conductscience.org/library/papers/28609654PubMed
934,608,482The EGFRvIII transcriptome in glioblastoma: A meta-omics analysis.Neuro Oncol2022https://conductscience.org/library/papers/34608482PubMed
1024,379,524Interferon-regulatory factors determine macrophage phenotype polarization.Mediators Inflamm2013https://conductscience.org/library/papers/24379524PubMed

1 to 10 of 84

See all 84 references

Cited by6

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 10 citations.

PMIDTitleJournalYearIn PapersSource
42,802,717Zebrafish against cancer: towards clinical relevance.Dis Model Mech2026https://conductscience.org/library/papers/42802717PubMed
42,129,557An X-linked long non-coding RNA, PTCHD1-AS, and the core features of autism.Nature2026https://conductscience.org/library/papers/42129557PubMed
41,828,372The Natural Triterpenoid Alisol B Overcomes Temozolomide Resistance in Glioblastoma Through Multi-Target Mechanisms: Coordinated Epigenetic, Metabolic, and Cell-Cycle Reprogramming.Int J Mol Sci2026https://conductscience.org/library/papers/41828372PubMed
41,598,285Antitumor Activity of All-Trans Retinoic Acid and Curcumin-Loaded BSA Nanoparticles Against U87 Glioblastoma Cells.Life (Basel)2026https://conductscience.org/library/papers/41598285PubMed
39,052,006Modeling glioblastoma.Elife2024https://conductscience.org/library/papers/39052006PubMed
39,052,000A syngeneic spontaneous zebrafish model of tp53-deficient, EGFRvIII, and PI3KCAH1047R-driven glioblastoma reveals inhibitory roles for inflammation during tumor initiation and relapse in vivo.Elife2024https://conductscience.org/library/papers/39052000PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data1

The data bank entries PubMed's record names. Trial numbers are under Trials.

Data bankAccession
GEOGSE246295

Source GEO

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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