Paper · 39901232
Visceral adipose tissue area and proportion provide distinct reflections of cardiometabolic outcomes in weight loss; pooled analysis of MRI-assessed CENTRAL and DIRECT PLUS dietary randomized controlled trials.
Klein H and 17 others. BMC Med, 2025. Cited by 17 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Visceral adipose tissue area and proportion provide distinct reflections of cardiometabolic outcomes in weight loss; pooled analysis of MRI-assessed CENTRAL and DIRECT PLUS dietary randomized controlled trials. Papers, record 39901232. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/39901232
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
Visceral adipose tissue area and proportion provide distinct reflections of cardiometabolic outcomes in weight loss; pooled analysis of MRI-assessed CENTRAL and DIRECT PLUS dietary randomized controlled trials.
- PubMed
- Publication types
- Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't
- PubMed
Topics10
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Intra-Abdominal Fat | Major topic |
| Weight Loss | Major topic |
| Humans | |
| Magnetic Resonance Imaging | |
| Male | |
| Female | |
| Middle Aged | |
| Adult | |
| Randomized Controlled Trials as Topic | |
| Subcutaneous Fat |
Source PubMed
Grants3
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by |
|---|---|---|---|---|
| project number 209933838 - SFB 1052; B11 | Deutsche Forschungsgemeinschaft | PubMed | ||
| 87472511 | Ministry of Health, State of Israel | PubMed | ||
| 3-13604 | Ministry of Science and Technology, Israel | PubMed |
Source PubMed
Trials2
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
| Trial | Title | The trial lists it as | Named in the paper's record | Source |
|---|---|---|---|---|
| NCT01530724 | Diet and Body Composition | Derived from the trial | Yes | ClinicalTrials.gov |
| NCT03020186 | Effects of Green-MED Diet Via the Gut-fat-brain Axis | Derived from the trial | Yes | ClinicalTrials.gov |
Comments and corrections1
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
| Kind | PMID | Title | In Papers |
|---|---|---|---|
| Erratum in | 39,966,884 | Correction: Visceral adipose tissue area and proportion provide distinct reflections of cardiometabolic outcomes in weight loss; pooled analysis of MRI-assessed CENTRAL and DIRECT PLUS dietary randomized controlled trials. | https://conductscience.org/library/papers/39966884 |
Source PubMed
References39
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 22,344,612 | Abdominal superficial subcutaneous fat: a putative distinct protective fat subdepot in type 2 diabetes. | Diabetes Care | 2012 | https://conductscience.org/library/papers/22344612 | PubMed |
| 2 | 36,175,997 | The effect of high-polyphenol Mediterranean diet on visceral adiposity: the DIRECT PLUS randomized controlled trial. | BMC Med | 2022 | https://conductscience.org/library/papers/36175997 | PubMed |
| 3 | 31,301,983 | Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement. | Lancet Diabetes Endocrinol | 2019 | https://conductscience.org/library/papers/31301983 | PubMed |
| 4 | 11,288,037 | Contributions of total body fat, abdominal subcutaneous adipose tissue compartments, and visceral adipose tissue to the metabolic complications of obesity. | Metabolism | 2001 | https://conductscience.org/library/papers/11288037 | PubMed |
| 5 | 17,576,866 | Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. | Circulation | 2007 | https://conductscience.org/library/papers/17576866 | PubMed |
| 6 | 30,612,535 | Impact of Visceral Adipose Tissue on Clinical Outcomes After Acute Ischemic Stroke. | Stroke | 2019 | https://conductscience.org/library/papers/30612535 | PubMed |
| 7 | 21,228,245 | Distribution of abdominal visceral and subcutaneous adipose tissue and metabolic syndrome in a Korean population. | Diabetes Care | 2011 | https://conductscience.org/library/papers/21228245 | PubMed |
| 8 | 3,796,297 | Contribution of intra-abdominal fat accumulation to the impairment of glucose and lipid metabolism in human obesity. | Metabolism | 1987 | https://conductscience.org/library/papers/3796297 | PubMed |
| 9 | 22,898,763 | The ratio of visceral to subcutaneous fat, a metric of body fat distribution, is a unique correlate of cardiometabolic risk. | Diabetologia | 2012 | https://conductscience.org/library/papers/22898763 | PubMed |
| 10 | 32,664,590 | Normalized Indices Derived from Visceral Adipose Mass Assessed by Magnetic Resonance Imaging and Their Correlation with Markers for Insulin Resistance and Prediabetes. | Nutrients | 2020 | https://conductscience.org/library/papers/32664590 | PubMed |
1 to 10 of 39
See all 39 referencesCited by17
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 17 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,881,236 | Incremental value of DXA-derived visceral versus total adiposity beyond routine anthropometric assessment for hypertension discrimination: a population-based study. | Hypertens Res | 2026 | https://conductscience.org/library/papers/42881236 | PubMed |
| 42,797,057 | Adipose Tissue Expandability as a Link Between Nutrition and Obesity-Related Metabolic Risk: Insights from Bariatric Surgery. | Nutrients | 2026 | https://conductscience.org/library/papers/42797057 | PubMed |
| 42,745,769 | Incremental effects of SGLT2 inhibitors, GLP-1 receptor agonists, and pioglitazone in type 2 diabetes and MASLD across Asian study settings: a systematic review and meta-analysis. | Front Endocrinol (Lausanne) | 2026 | https://conductscience.org/library/papers/42745769 | PubMed |
| 42,718,954 | Central adiposity and sex influence lipid and glucose indices in Mexican adults: implications for metabolic risk assessment. | Front Nutr | 2026 | https://conductscience.org/library/papers/42718954 | PubMed |
| 42,652,111 | The Ketogenic Diet in the Prevention and Treatment of Hypertension (HTN). | Biomedicines | 2026 | https://conductscience.org/library/papers/42652111 | PubMed |
| 42,450,537 | The Serpin Superfamily in Adipose Tissue Remodeling: Molecular Drivers of Immune-Metabolic Crosstalk and Insulin Sensitivity. | Biology (Basel) | 2026 | https://conductscience.org/library/papers/42450537 | PubMed |
| 42,337,820 | A Four-Week Treatment With Dapagliflozin Is Associated With a Reduction in Insulin-Stimulated Renal Cortical Glucose Uptake: A Post Hoc Analysis From a Pilot Study. | Diabetes Obes Metab | 2026 | https://conductscience.org/library/papers/42337820 | PubMed |
| 42,303,809 | Role of systemic and epicardial adipose tissue in cardiometabolic disease. | Nat Rev Cardiol | 2026 | https://conductscience.org/library/papers/42303809 | PubMed |
| 42,290,836 | Visceral fat area and visceral-to-subcutaneous fat ratio are more strongly associated with residual cholesterol than conventional anthropometric indices in adults with type 2 diabetes. | Front Endocrinol (Lausanne) | 2026 | https://conductscience.org/library/papers/42290836 | PubMed |
| 42,288,872 | Gestational diabetes as an inter-generational cardiometabolic risk factor: spotlight on emerging exerkines. | Cardiovasc Diabetol | 2026 | https://conductscience.org/library/papers/42288872 | PubMed |
1 to 10 of 17
See all 17 cited byGenes3
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| CRP | 1,401 | PubTator's text mining | https://conductscience.org/library/genes/1401 | NCBI Gene |
| LEP | 3,952 | PubTator's text mining | https://conductscience.org/library/genes/3952 | NCBI Gene |
| RARRES2 | 5,919 | PubTator's text mining | https://conductscience.org/library/genes/5919 | NCBI Gene |
Drugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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