Paper · 40066261

Comprehensive investigation of proteoglycan gene expression in breast cancer: Discovery of a unique proteoglycan gene signature linked to the malignant phenotype.

Buraschi S and 3 others. Proteoglycan Res, 2025. Cited by 8 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Comprehensive investigation of proteoglycan gene expression in breast cancer: Discovery of a unique proteoglycan gene signature linked to the malignant phenotype. Papers, record 40066261. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/40066261

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Comprehensive investigation of proteoglycan gene expression in breast cancer: Discovery of a unique proteoglycan gene signature linked to the malignant phenotype.; PubMed
Journal: Proteoglycan Res; PubMed
Year: 2025; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/40066261/; PubMed
DOI: https://doi.org/10.1002/pgr2.70014; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC11893098/; PubMed
The journal: https://conductscience.org/library/journal-index/9918589889006676; PubMed
Citations, by iCite: 8; iCite
Relative citation ratio, by iCite: 2.35, provisional; iCite
Revised in PubMed: 2025-03-13; PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	ORCID iD
1	Buraschi S	Simone	https://orcid.org/0000-0002-4233-7627
2	Pascal G	Gabriel	https://orcid.org/0009-0003-3713-4870
3	Liberatore F	Federico	https://orcid.org/0000-0001-9900-5108
4	Iozzo RV	Renato V	https://orcid.org/0000-0002-5908-5112

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants2

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
R01 CA245311	NCI NIH HHS	United States	R01CA245311	PubMed and NIH	NIH RePORTER
R03 CA270830	NCI NIH HHS	United States	R03CA270830	PubMed and NIH	NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References215

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	30,130,584	Matrix modeling and remodeling: A biological interplay regulating tissue homeostasis and diseases.	Matrix Biol	2019	https://conductscience.org/library/papers/30130584	PubMed
2	9,024,701	Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility.	J Cell Biol	1997	https://conductscience.org/library/papers/9024701	PubMed
3	10,913,155	Sustained down-regulation of the epidermal growth factor receptor by decorin. A mechanism for controlling tumor growth in vivo.	J Biol Chem	2000	https://conductscience.org/library/papers/10913155	PubMed
4	39,045,898	Decorin attenuates hypertrophic scar fibrosis via TGFβ/Smad signalling.	Exp Dermatol	2024	https://conductscience.org/library/papers/39045898	PubMed
5	25,661,523	Pivotal role for decorin in angiogenesis.	Matrix Biol	2015	https://conductscience.org/library/papers/25661523	PubMed
6	18,463,092	Biological functions of the small leucine-rich proteoglycans: from genetics to signal transduction.	J Biol Chem	2008	https://conductscience.org/library/papers/18463092	PubMed
7	32,209,654	Catabolic degradation of endothelial VEGFA via autophagy.	J Biol Chem	2020	https://conductscience.org/library/papers/32209654	PubMed
8	15,383,330	Syndecan-1 ectodomain regulates matrix-dependent signaling in human breast carcinoma cells.	Exp Cell Res	2004	https://conductscience.org/library/papers/15383330	PubMed
9	23,029,096	Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model.	PLoS One	2012	https://conductscience.org/library/papers/23029096	PubMed
10	37,936,982	PRELP secreted from mural cells protects the function of blood brain barrier through regulation of endothelial cell-cell integrity.	Front Cell Dev Biol	2023	https://conductscience.org/library/papers/37936982	PubMed

1 to 10 of 215

See all 215 references

Cited by6

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 8 citations.

PMID	Title	Journal	Year	In Papers	Source
42,569,117	Introduction to the Special Issue on Proteoglycan and Glycosaminoglycan Biology.	Proteoglycan Res	2026	https://conductscience.org/library/papers/42569117	PubMed
42,509,832	Proteoglycans as Molecular Regulators of Bone Metastasis: Extracellular Matrix Remodeling, Tumor-Bone Crosstalk, Dormancy, and Therapeutic Opportunities.	Biomolecules	2026	https://conductscience.org/library/papers/42509832	PubMed
41,463,344	Proteoglycans in Breast Cancer: Friends and Foes.	Biomolecules	2025	https://conductscience.org/library/papers/41463344	PubMed
41,282,833	Linking spatial omics to patient phenotypes at the population scale by BSNMani: Bayesian scalar-on-network regression with manifold learning.	medRxiv	2025	https://conductscience.org/library/papers/41282833	PubMed
41,112,955	Decorin Evokes a Pro-lysosomal Pathway in Lymphatic Endothelial Cells.	Proteoglycan Res	2025	https://conductscience.org/library/papers/41112955	PubMed
40,645,813	Proteoglycans are protagonists in autophagy, lymphangiogenesis, and neurodegenerative diseases.	Trends Cell Biol	2026	https://conductscience.org/library/papers/40645813	PubMed

Genes6

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
ASPN	54,829	PubTator's text mining	https://conductscience.org/library/genes/54829	NCBI Gene
DCN	1,634	PubTator's text mining	https://conductscience.org/library/genes/1634	NCBI Gene
PODN	127,435	PubTator's text mining	https://conductscience.org/library/genes/127435	NCBI Gene
PRELP	5,549	PubTator's text mining	https://conductscience.org/library/genes/5549	NCBI Gene
SDC1	6,382	PubTator's text mining	https://conductscience.org/library/genes/6382	NCBI Gene
SRGN	5,552	PubTator's text mining	https://conductscience.org/library/genes/5552	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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