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Paper · 40076745

Anti-Bacterial and Anti-Inflammatory Properties of Sophoridine and Its Effect on Diarrhea in Mice.

Wang J and 6 others. Int J Mol Sci, 2025. Cited by 6 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Anti-Bacterial and Anti-Inflammatory Properties of Sophoridine and Its Effect on Diarrhea in Mice. Papers, record 40076745. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/40076745

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Anti-Bacterial and Anti-Inflammatory Properties of Sophoridine and Its Effect on Diarrhea in Mice.
PubMed
Journal
Int J Mol Sci
PubMed
Year
2025
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
6
iCite
Relative citation ratio, by iCite
2.04, provisional
iCite
Revised in PubMed
2025-05-12
PubMed

Authors7

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Wang JJiaxue
2Tao HHui
3Fan QQiuyu
4Wang ZZhenlonghttps://orcid.org/0009-0001-9889-2021
5Han BBinghttps://orcid.org/0009-0006-8457-9583
6Wang XXiuminhttps://orcid.org/0000-0002-2008-856X
7Wang JJingquan

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Anti-Inflammatory AgentsMajor topic
AlkaloidsMajor topic
Anti-Bacterial AgentsMajor topic
QuinolizinesMajor topic
DiarrheaMajor topic
Animals
Mice
RAW 264.7 Cells
Matrines
Mice, Inbred BALB C
Escherichia coli
Cytokines
Male
Disease Models, Animal
NF-kappa B

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
2022xjkk0404'Third Xinjiang Scientific Expedition Program' supported by the Ministry of Science and Tech-nology of the People's Republic of China, 2022-2025PubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References60

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
131,798,551Inhibitory Effect of Two Traditional Chinese Medicine Monomers, Berberine and Matrine, on the Quorum Sensing System of Antimicrobial-Resistant Escherichia coli.Front Microbiol2019https://conductscience.org/library/papers/31798551PubMed
233,937,093Gut Microbiota and Diarrhea: An Updated Review.Front Cell Infect Microbiol2021https://conductscience.org/library/papers/33937093PubMed
322,121,777[Sophoridine inhibits NF-kappaB signaling pathway activation in kidney tissue of endotoxemia mice].Yao Xue Xue Bao2011https://conductscience.org/library/papers/22121777PubMed
430,743,078Protective effects of berberine hydrochloride on DSS-induced ulcerative colitis in rats.Int Immunopharmacol2019https://conductscience.org/library/papers/30743078PubMed
516,369,557Immune cell migration in inflammation: present and future therapeutic targets.Nat Immunol2005https://conductscience.org/library/papers/16369557PubMed
630,718,924IL-10 produced by macrophages regulates epithelial integrity in the small intestine.Sci Rep2019https://conductscience.org/library/papers/30718924PubMed
724,211,392Hymenaea stigonocarpa Mart. ex Hayne: A tropical medicinal plant with intestinal anti-inflammatory activity in TNBS model of intestinal inflammation in rats.J Ethnopharmacol2014https://conductscience.org/library/papers/24211392PubMed
831,575,657Sophoridine Inhibits Human Colorectal Cancer Progression via Targeting MAPKAPK2.Mol Cancer Res2019https://conductscience.org/library/papers/31575657PubMed
911,846,609Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.Methods2001https://conductscience.org/library/papers/11846609PubMed
1033,718,223Sophoridine Inhibits the Tumour Growth of Non-Small Lung Cancer by Inducing Macrophages M1 Polarisation via MAPK-Mediated Inflammatory Pathway.Front Oncol2021https://conductscience.org/library/papers/33718223PubMed

1 to 10 of 60

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Cited by5

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 6 citations.

PMIDTitleJournalYearIn PapersSource
42,797,923Sophora japonica Extract Supplementation Facilitates Piglets' Early Weaning Transition by Alleviating Intestinal Oxidative Stress, Inflammation, and Microbiota Dysbiosis.Vet Sci2026https://conductscience.org/library/papers/42797923PubMed
42,694,409Traditional Chinese medicine modulates tumor-associated macrophages to suppress gastric cancer progression: mechanisms and therapeutic potential.Front Oncol2026https://conductscience.org/library/papers/42694409PubMed
42,528,752Sophoridine attenuates osteoarthritis progression: association with suppression of chondrocyte pyroptosis via inhibiting NF-κB signaling pathway.Front Pharmacol2026https://conductscience.org/library/papers/42528752PubMed
41,974,989Sophflarines F-K: matrine-based alkaloids with a rare aromatic system from Sophora flavescens and their anti-inflammatory and synergistic antibacterial effects.Nat Prod Bioprospect2026https://conductscience.org/library/papers/41974989PubMed
40,612,058Mechanism of Shi-Yang-Xiao lotion in alleviating perianal eczema based on network pharmacology and experimental validation.Front Mol Biosci2025https://conductscience.org/library/papers/40612058PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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