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Paper · 40208485

Perillic acid disrupts the specification of germ layers by upregulating the FGF/MAPK pathway.

Yoon GH and 3 others. Genes Genomics, 2025. Cited by 2 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Perillic acid disrupts the specification of germ layers by upregulating the FGF/MAPK pathway. Papers, record 40208485. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/40208485

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Perillic acid disrupts the specification of germ layers by upregulating the FGF/MAPK pathway.
PubMed
Journal
Genes Genomics
PubMed
Year
2025
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
2
iCite
Revised in PubMed
2026-11-03
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Yoon GHGang-Hohttps://orcid.org/0009-0002-6755-6225
2Park DSDong-Seokhttps://orcid.org/0000-0003-3543-2789
3Kim MSMyeoung Suhttps://orcid.org/0009-0000-1874-3484
4Choi SCSun-Cheolhttps://orcid.org/0000-0003-3366-894X

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
MAP Kinase Signaling SystemMajor topic
Germ LayersMajor topic
Fibroblast Growth FactorsMajor topic
Animals
Xenopus laevis
Gene Expression Regulation, Developmental
Embryo, Nonmammalian
Xenopus Proteins
Cell Differentiation
Signal Transduction
Body Patterning
Neural Crest
Embryonic Development

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
2020R1F1A1075945, 2022R1A2C1011769National Research Foundation of KoreaPubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References28

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,811,161In situ hybridization: an improved whole-mount method for Xenopus embryos.Methods Cell Biol1991https://conductscience.org/library/papers/1811161PubMed
229,453,943MAPK and PI3K signaling: At the crossroads of neural crest development.Dev Biol2018https://conductscience.org/library/papers/29453943PubMed
311,782,399Beta-catenin, MAPK and Smad signaling during early Xenopus development.Development2002https://conductscience.org/library/papers/11782399PubMed
47,925,289eFGF regulates Xbra expression during Xenopus gastrulation.EMBO J1994https://conductscience.org/library/papers/7925289PubMed
517,234,915Integration of TGF-beta and Ras/MAPK signaling through p53 phosphorylation.Science2007https://conductscience.org/library/papers/17234915PubMed
610,910,771Signaling specificities of fibroblast growth factor receptors in early Xenopus embryo.J Cell Sci2000https://conductscience.org/library/papers/10910771PubMed
711,446,774Effect of perillic acid, a putative isoprenylation inhibitor, on the cultured rat lens.Exp Eye Res2001https://conductscience.org/library/papers/11446774PubMed
817,289,590Balancing BMP signaling through integrated inputs into the Smad1 linker.Mol Cell2007https://conductscience.org/library/papers/17289590PubMed
938,637,565Xbra modulates the activity of linker region phosphorylated Smad1 during Xenopus development.Sci Rep2024https://conductscience.org/library/papers/38637565PubMed
1020,978,071FGF signalling: diverse roles during early vertebrate embryogenesis.Development2010https://conductscience.org/library/papers/20978071PubMed

1 to 10 of 28

See all 28 references

Cited by2

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 2 citations.

PMIDTitleJournalYearIn PapersSource
42,429,045FGFR1 signaling in rheumatoid arthritis: Mechanisms of bone destruction and therapeutic targeting (Review).Int J Mol Med2026https://conductscience.org/library/papers/42429045PubMed
42,371,315BMP/Ventx1.1 axis modulates the multiciliogenesis in the early Xenopus epidermis.Genes Genomics2026https://conductscience.org/library/papers/42371315PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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