Paper · 40445765
Genomic analyses identify 15 risk loci and reveal HDAC2, SOX2-OT, and IGF2BP2 in a naturally occurring canine model of gastric cancer.
Cook SR and 11 others. Proc Natl Acad Sci U S A, 2025. Cited by 3 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Genomic analyses identify 15 risk loci and reveal HDAC2, SOX2-OT, and IGF2BP2 in a naturally occurring canine model of gastric cancer. Papers, record 40445765. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/40445765
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Genomic analyses identify 15 risk loci and reveal HDAC2, SOX2-OT, and IGF2BP2 in a naturally occurring canine model of gastric cancer.
- PubMed
Topics11
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Stomach Neoplasms | Major topic |
| Dog Diseases | Major topic |
| SOXB1 Transcription Factors | Major topic |
| RNA-Binding Proteins | Major topic |
| Animals | |
| Dogs | |
| Genome-Wide Association Study | |
| Genetic Predisposition to Disease | |
| Disease Models, Animal | |
| Polymorphism, Single Nucleotide | |
| Risk Factors |
Source PubMed
Grants2
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by | Source |
|---|---|---|---|---|---|
| Intramural Program | HHS | NIH | National Human Genome Research Institute (NHGRI) | PubMed | PubMed | ||
| ZIAHG200377 | NIH | NIH RePORTER |
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections1
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
| Kind | PMID | Title | In Papers |
|---|---|---|---|
| Update of | 39,372,775 |
Source PubMed
References138
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 25,166,616 | A COLQ missense mutation in Labrador Retrievers having congenital myasthenic syndrome. | PLoS One | 2014 | https://conductscience.org/library/papers/25166616 | PubMed |
| 2 | 15,016,327 | Expression of RCAS1 in human gastric carcinoma: a potential mechanism of immune escape. | Cancer Sci | 2004 | https://conductscience.org/library/papers/15016327 | PubMed |
| 3 | 34,195,685 | CD101 genetic variants modify regulatory and conventional T cell phenotypes and functions. | Cell Rep Med | 2021 | https://conductscience.org/library/papers/34195685 | PubMed |
| 4 | 23,514,604 | Breed predisposition to canine gastric carcinoma--a study based on the Norwegian canine cancer register. | Acta Vet Scand | 2013 | https://conductscience.org/library/papers/23514604 | PubMed |
| 5 | 24,668,547 | Differential expression of histone deacetylase and acetyltransferase genes in gastric cancer and their modulation by trichostatin A. | Tumour Biol | 2014 | https://conductscience.org/library/papers/24668547 | PubMed |
| 6 | 36,266,566 | Kelch-like proteins in the gastrointestinal tumors. | Acta Pharmacol Sin | 2023 | https://conductscience.org/library/papers/36266566 | PubMed |
| 7 | 25,198,863 | The ubiquitin ligase PDZRN3 is required for vascular morphogenesis through Wnt/planar cell polarity signalling. | Nat Commun | 2014 | https://conductscience.org/library/papers/25198863 | PubMed |
| 8 | 34,135,125 | Proteomic analysis identifies the E3 ubiquitin ligase Pdzrn3 as a regulatory target of Wnt5a-Ror signaling. | Proc Natl Acad Sci U S A | 2021 | https://conductscience.org/library/papers/34135125 | PubMed |
| 9 | 38,572,751 | Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. | CA Cancer J Clin | 2024 | https://conductscience.org/library/papers/38572751 | PubMed |
| 10 | 20,627,832 | HLA-DRB1*03 and DRB1*04 are associated with atrophic gastritis in an Italian population. | Dig Liver Dis | 2010 | https://conductscience.org/library/papers/20627832 | PubMed |
1 to 10 of 138
See all 138 referencesCited by3
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 3 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,730,512 | Towards a Standard Threshold for Genome Wide Significance in Dogs. | Anim Genet | 2026 | https://conductscience.org/library/papers/42730512 | PubMed |
| 41,131,406 | Silencing SOX2OT reduces viability and migration in lung cancer cells via lncRNA and protein regulation. | Med Oncol | 2025 | https://conductscience.org/library/papers/41131406 | PubMed |
| 40,445,765 | Genomic analyses identify 15 risk loci and reveal HDAC2, SOX2-OT, and IGF2BP2 in a naturally occurring canine model of gastric cancer. | Proc Natl Acad Sci U S A | 2025 | https://conductscience.org/library/papers/40445765 | PubMed |
Genes0
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
None in this release.
Drugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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