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Paper · 40499561

Kidney organoid models of polycystic kidney disease: challenges and future directions.

Afrin H and 5 others. Am J Physiol Renal Physiol, 2025. Cited by 4 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Kidney organoid models of polycystic kidney disease: challenges and future directions. Papers, record 40499561. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/40499561

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Kidney organoid models of polycystic kidney disease: challenges and future directions.
PubMed
Journal
Am J Physiol Renal Physiol
PubMed
Year
2025
PubMed
Publication types
Journal Article, Review, Research Support, N.I.H., Extramural
PubMed
Citations, by iCite
4
iCite
Revised in PubMed
2026-06-05
PubMed

Authors6

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Afrin HHumayra
2Qamar UUsama
3Robichaud JHJielu Hao
4Ellabbad MMohammad
5Harris PCPeter C
6Gupta NNavinhttps://orcid.org/0009-0003-7005-4098

Source PubMed

Topics8

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
OrganoidsMajor topic
KidneyMajor topic
Polycystic Kidney DiseasesMajor topic
Humans
Animals
Induced Pluripotent Stem Cells
Polycystic Kidney, Autosomal Dominant
Phenotype

Source PubMed

Grants26

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
P30 DK090728NIDDK NIH HHSUnited StatesP30DK090728PubMed and NIHNIH RePORTER
U01 DK114866NIDDK NIH HHSUnited StatesU01DK114866PubMed and NIHNIH RePORTER
U01 DK133097NIDDK NIH HHSUnited StatesU01DK133097PubMed and NIHNIH RePORTER
UL1TR002377HHS | NIH | National Center for Advancing Translational Sciences (NCATS)UL1TR002377PubMed and NIHNIH RePORTER
U24DK126110HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)U24DK126110PubMed and NIHNIH RePORTER
U01 DK114933NIDDK NIH HHSUnited StatesU01DK114933PubMed and NIHNIH RePORTER
U01 DK114908NIDDK NIH HHSUnited StatesU01DK114908PubMed and NIHNIH RePORTER
U01 DK133095NIDDK NIH HHSUnited StatesU01DK133095PubMed and NIHNIH RePORTER
U24 DK126110NIDDK NIH HHSUnited StatesU24DK126110PubMed and NIHNIH RePORTER
U01 DK114907NIDDK NIH HHSUnited StatesU01DK114907PubMed and NIHNIH RePORTER

1 to 10 of 26

See all 26 grants

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References146

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
131,395,384Application of physiological shear stress to renal tubular epithelial cells.Methods Cell Biol2019https://conductscience.org/library/papers/31395384PubMed
217,434,405Autosomal dominant polycystic kidney disease.Lancet2007https://conductscience.org/library/papers/17434405PubMed
335,478,224Modelling ciliopathy phenotypes in human tissues derived from pluripotent stem cells with genetically ablated cilia.Nat Biomed Eng2022https://conductscience.org/library/papers/35478224PubMed
430,573,816Evaluation of variability in human kidney organoids.Nat Methods2019https://conductscience.org/library/papers/30573816PubMed
530,093,605Structure of the human PKD1-PKD2 complex.Science2018https://conductscience.org/library/papers/30093605PubMed
631,303,547Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network.Cell Stem Cell2019https://conductscience.org/library/papers/31303547PubMed
737,256,068Kidney transcriptome and cystic kidney disease genes in zebrafish.Front Physiol2023https://conductscience.org/library/papers/37256068PubMed
84,780,695Stimulation by vasopressin of glycogen breakdown and gluconeogenesis in the perfused rat liver.Biochem J1973https://conductscience.org/library/papers/4780695PubMed
935,134,221
An update on the use of tolvaptan for autosomal dominant polycystic kidney disease: consensus statement on behalf of the ERA Working Group on Inherited Kidney Disorders, the European Rare Kidney Disease Reference Network and Polycystic Kidney Disease International.
Nephrol Dial Transplant2022https://conductscience.org/library/papers/35134221PubMed
1027,493,259Variable Cyst Development in Autosomal Dominant Polycystic Kidney Disease: The Biologic Context.J Am Soc Nephrol2016https://conductscience.org/library/papers/27493259PubMed

1 to 10 of 146

See all 146 references

Cited by2

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 4 citations.

PMIDTitleJournalYearIn PapersSource
42,136,860Advances and future perspectives of kidney organoid technology in renal disease research and clinical translation.Front Med (Lausanne)2026https://conductscience.org/library/papers/42136860PubMed
41,852,449Kidney organoid vascularization: current advancements in the field.Regen Ther2026https://conductscience.org/library/papers/41852449PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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