Paper405672

Structure-function relations in phosphorylcholine-binding mouse myeloma proteins.

Goetze AM and 1 other. Proc Natl Acad Sci U S A, 1977. Cited by 22 papers, by iCite.

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ConductScience Library. Structure-function relations in phosphorylcholine-binding mouse myeloma proteins. Papers, record 405672. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/405672

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Structure-function relations in phosphorylcholine-binding mouse myeloma proteins.; PubMed
Journal: Proc Natl Acad Sci U S A; PubMed
Year: 1977; PubMed
Publication types: Comparative Study, Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/405672/; PubMed
DOI: https://doi.org/10.1073/pnas.74.5.2109; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC431084/; PubMed
The journal: https://conductscience.org/library/journal-index/7505876; PubMed
Citations, by iCite: 22; iCite
Relative citation ratio, by iCite: 0.5; iCite
Revised in PubMed: 2019-05-01; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Goetze AM	A M
2	Richards JH	J H

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Binding Sites, Antibody	Major topic
Choline	Major topic
Immunoglobulin Variable Region	Major topic
Myeloma Proteins	Major topic
Phosphorylcholine	Major topic
Cell Line
Haptens
Immunoglobulin Heavy Chains
Immunoglobulin Light Chains
Kinetics
Magnetic Resonance Spectroscopy
Neoplasms, Experimental
Phosphates
Plasmacytoma
Protein Binding
Structure-Activity Relationship

Source PubMed

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References17

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	13,987,717	Kinetics of antibody-hapten interactions.	Ann N Y Acad Sci	1963	https://conductscience.org/library/papers/13987717	PubMed
2	556,944	Magnetic resonance studies of the binding site interactions between phosphorylcholine and specific mouse myeloma immunoglobulin.	Biochemistry	1977	https://conductscience.org/library/papers/556944	PubMed
3	827,496	Structural basis for the specificity of phosphorylcholine-binding immunoglobulins.	Immunochemistry	1976	https://conductscience.org/library/papers/827496	PubMed
4	4,213,527	Variable region sequence of the heavy chain from a phosphorylcholine binding myeloma protein.	Biochemistry	1974	https://conductscience.org/library/papers/4213527	PubMed
5	4,826,892	Kinetic mapping of the antibody combining site by chemical relaxation spectrometry.	Biochemistry	1974	https://conductscience.org/library/papers/4826892	PubMed
6	4,129,807	Immunoglobulin structure: amino terminal sequences of mouse myeloma proteins that bind phosphorylcholine.	Science	1974	https://conductscience.org/library/papers/4129807	PubMed
7	4,103,271	Specificity for phosphorylcholine of six murine myeloma proteins reactive with Pneumococcus C polysaccharide and beta-lipoprotein.	Biochemistry	1971	https://conductscience.org/library/papers/4103271	PubMed
8	4,107,359	Reconstitution from subunits of the hapten binding sites and idiotypic determinants of mouse anti-phosphorylcholine myeloma proteins.	J Immunol	1971	https://conductscience.org/library/papers/4107359	PubMed
9	4,101,363	Common individual antigenic determinants in five of eight BALB-c IgA myeloma proteins that bind phosphoryl choline.	J Exp Med	1970	https://conductscience.org/library/papers/4101363	PubMed
10	4,108,806	Kinetic studies on antibody-hapten reactions. I. Reactions with antibodies and their univalent Fab' fragments.	Immunochemistry	1971	https://conductscience.org/library/papers/4108806	PubMed
11	4,175,691	Three IgA myeloma immunoglobulins from the BALB/ mouse: precipitation with pneumococcal C polysaccharide.	Science	1968	https://conductscience.org/library/papers/4175691	PubMed
12	4,588,682	The binding peoperties of anti-phosphorylcholine mouse myeloma proteins as measured by protein fluorescence.	J Biol Chem	1973	https://conductscience.org/library/papers/4588682	PubMed
13	46,916	Structural, functional, and idiotypic characteristics of a phosphorylcholine-binding IgA myeloma protein of C57BL/ka allotype.	J Exp Med	1975	https://conductscience.org/library/papers/46916	PubMed
14	4,555,516	Immunoglobulin-producing tumors and myeloma proteins of mice.	Physiol Rev	1972	https://conductscience.org/library/papers/4555516	PubMed
15	4,530,984	The three-dimensional structure of a phosphorylcholine-binding mouse immunoglobulin Fab and the nature of the antigen binding site.	Proc Natl Acad Sci U S A	1974	https://conductscience.org/library/papers/4530984	PubMed
16	5,059,886	Affinity labeling of a phosphorylcholine binding mouse myeloma protein.	Biochemistry	1972	https://conductscience.org/library/papers/5059886	PubMed
17	813,561	The organization, expression, and evolution of antibody genes and other multigene families.	Annu Rev Genet	1975	https://conductscience.org/library/papers/813561	PubMed

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Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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NIH RePORTER's grant and paper linksPublic domain
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PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
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NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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