Paper · 41252147

Structural basis for Lamassu-based antiviral immunity and its evolution from DNA repair machinery.

Haudiquet M and 12 others. Proc Natl Acad Sci U S A, 2025. Cited by 10 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Structural basis for Lamassu-based antiviral immunity and its evolution from DNA repair machinery. Papers, record 41252147. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41252147

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Structural basis for Lamassu-based antiviral immunity and its evolution from DNA repair machinery.; PubMed
Journal: Proc Natl Acad Sci U S A; PubMed
Year: 2025; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/41252147/; PubMed
DOI: https://doi.org/10.1073/pnas.2519643122; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC12663957/; PubMed
The journal: https://conductscience.org/library/journal-index/7505876; PubMed
Citations, by iCite: 10; iCite
Relative citation ratio, by iCite: 2.03, provisional; iCite
Revised in PubMed: 2026-08-13; PubMed

Authors13

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	ORCID iD
1	Haudiquet M	Matthieu	https://orcid.org/0000-0002-0878-2209
2	Chakravarti A	Arpita	https://orcid.org/0009-0009-3267-8450
3	Zhang Z	Zhiying
4	Ramirez JL	Josephine L
5	Herrero Del Valle A	Alba	https://orcid.org/0000-0001-8153-6146
6	Olinares PDB	Paul Dominic B	https://orcid.org/0000-0002-3429-6618
7	Lavenir R	Rachel
8	Ahmed MA	Massilia Aït
9	de la Cruz MJ	M Jason	https://orcid.org/0000-0002-8573-5406
10	Chait BT	Brian T	https://orcid.org/0000-0003-3524-557X

1 to 10 of 13Source PubMed

See all 13 authors

Topics7

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
DNA Repair	Major topic
Vibrio cholerae	Major topic
Bacterial Proteins	Major topic
Evolution, Molecular
Cryoelectron Microscopy
Bacteriophages
Virus Replication

Source PubMed

Grants7

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
PECAN 101040529	ERC		PECAN101040	PubMed	NIH RePORTER
AI141507	NIH HHS	United States		PubMed	PubMed
GM145888	NIH HHS	United States		PubMed	PubMed
P30 CA008748	NCI NIH HHS	United States	P30CA008748	PubMed	NIH RePORTER
GM129430	NIH HHS	United States		PubMed	PubMed
P30-CA008748	NIH HHS	United States	P30CA008748	PubMed	NIH RePORTER
R01 GM145888	NIGMS NIH HHS	United States	R01GM145888	PubMed	NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections1

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

Kind	PMID	Title	In Papers
Update of	40,236,079

Source PubMed

References51

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	29,179,671	Phylogenomics of Cas4 family nucleases.	BMC Evol Biol	2017	https://conductscience.org/library/papers/29179671	PubMed
2	39,970,912	Reprogrammable RNA-targeting CRISPR systems evolved from RNA toxin-antitoxins.	Cell	2025	https://conductscience.org/library/papers/39970912	PubMed
3	29,371,424	Systematic discovery of antiphage defense systems in the microbial pangenome.	Science	2018	https://conductscience.org/library/papers/29371424	PubMed
4	36,419,248	DALI shines a light on remote homologs: One hundred discoveries.	Protein Sci	2023	https://conductscience.org/library/papers/36419248	PubMed
5	32,974,386	Formation of Complexes Between O Proteins and Replication Origin Regions of Shiga Toxin-Converting Bacteriophages.	Front Mol Biosci	2020	https://conductscience.org/library/papers/32974386	PubMed
6	39,626,662	Loop-extrusion-mediated plasmid DNA cleavage by the bacterial SMC Wadjet complex.	Mol Cell	2025	https://conductscience.org/library/papers/39626662	PubMed
7	35,538,097	Systematic and quantitative view of the antiviral arsenal of prokaryotes.	Nat Commun	2022	https://conductscience.org/library/papers/35538097	PubMed
8	32,894,288	Comprehensive classification of ABC ATPases and their functional radiation in nucleoprotein dynamics and biological conflict systems.	Nucleic Acids Res	2020	https://conductscience.org/library/papers/32894288	PubMed
9	39,002,129	DdmABC-dependent death triggered by viral palindromic DNA sequences.	Cell Rep	2024	https://conductscience.org/library/papers/39002129	PubMed
10	25,488,578	Evolution of adaptive immunity from transposable elements combined with innate immune systems.	Nat Rev Genet	2015	https://conductscience.org/library/papers/25488578	PubMed

1 to 10 of 51

See all 51 references

Cited by15

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 10 citations.

PMID	Title	Journal	Year	In Papers	Source
42,907,588	Molecular control of bacterial immunity.	Nat Struct Mol Biol	2026	https://conductscience.org/library/papers/42907588	PubMed
42,905,107	Taming Mre11-Rad50 at Telomeres: Convergent Strategies for Chromosome-End Protection Across Evolution.	Bioessays	2026	https://conductscience.org/library/papers/42905107	PubMed
42,881,220	Single Staphylococcus aureus SauUSI restriction enzyme motors fragment methylated DNA.	Nat Chem Biol	2026	https://conductscience.org/library/papers/42881220	PubMed
42,856,579	RecBCD Prevents Bacterial Autoimmunity by Clearing Self-DNA Ends Produced During Replication Termination.	bioRxiv	2026	https://conductscience.org/library/papers/42856579	PubMed
42,755,366	Shuttling, swapping, and mixing: the rapid modular evolution of antiviral repertoires in temperate phages and their satellites.	Nucleic Acids Res	2026	https://conductscience.org/library/papers/42755366	PubMed
42,587,116	Shared principles of human and bacterial antiviral immunity.	Nature	2026	https://conductscience.org/library/papers/42587116	PubMed
42,462,716	Gabija restricts phage circularization and DNA replication.	Cell Host Microbe	2026	https://conductscience.org/library/papers/42462716	PubMed
42,106,568	Structural insights into the assembly and function of Retron Ec78 PtuAB.	Commun Biol	2026	https://conductscience.org/library/papers/42106568	PubMed
41,922,762	Evolution of pandemic cholera at its global source.	Nature	2026	https://conductscience.org/library/papers/41922762	PubMed
41,708,866	Nucleotide signals coordinate activation and inhibition of bacterial immunity.	Nature	2026	https://conductscience.org/library/papers/41708866	PubMed

1 to 10 of 15

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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