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Paper4126771

Overlap stimulation of primary and secondary B cells by cross-reacting determinants.

Klinman NR and 2 others. J Exp Med, 1973. Cited by 45 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Overlap stimulation of primary and secondary B cells by cross-reacting determinants. Papers, record 4126771. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4126771

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Overlap stimulation of primary and secondary B cells by cross-reacting determinants.
PubMed
Journal
J Exp Med
PubMed
Year
1973
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
45
iCite
Relative citation ratio, by iCite
0.76
iCite
Revised in PubMed
2019-05-08
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Klinman NRN R
2Press JLJ L
3Segal GPG P

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antibody-Producing CellsMajor topic
Antigen-Antibody ReactionsMajor topic
B-LymphocytesMajor topic
Cross ReactionsMajor topic
Lymphocyte ActivationMajor topic
Animals
Antibody Specificity
Cells, Cultured
Epitopes
Mice
Mice, Inbred BALB C
Nitrophenols
Spleen

Source PubMed

References11

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
15,841,047Anti-bovine serum albumin specificity and binding affinity after termination of tolerance to bovine serum albumin.J Immunol1965https://conductscience.org/library/papers/5841047PubMed
25,922,742Disquisitions of Original Antigenic Sin. I. Evidence in man.J Exp Med1966https://conductscience.org/library/papers/5922742PubMed
35,305,881General methods for the study of cells and serum during the immune response: the response to dinitrophenyl in mice.Clin Exp Immunol1969https://conductscience.org/library/papers/5305881PubMed
44,898,221Degeneracy in the secondary immune response: stimulation of antibody formation by cross-reacting antigens.Isr J Med Sci1969https://conductscience.org/library/papers/4898221PubMed
55,344,479Antibody with homogeneous antigen binding produced by splenic foci in organ culture.Immunochemistry1969https://conductscience.org/library/papers/5344479PubMed
65,103,350Regain of homogeneous binding activity after recombination of chains of "mono- focal" antibody.J Immunol1971https://conductscience.org/library/papers/5103350PubMed
74,114,497The mechanism of antigenic stimulation of primary and secondary clonal precursor cells.J Exp Med1972https://conductscience.org/library/papers/4114497PubMed
85,066,512Initiation of antibody responses by different classes of lymphocytes. V. Fundamental changes in the physiological characteristics of virgin thymus-independent ("B") lymphocytes and "B" memory cells.J Exp Med1972https://conductscience.org/library/papers/5066512PubMed
94,577,410Original antigenic sin at the cellular level. II. Specificity of the antibodies produced by individual cells.Eur J Immunol1973https://conductscience.org/library/papers/4577410PubMed
104,736,831Monoclonal production of both IgM and IgG1 antihapten antibody.J Exp Med1973https://conductscience.org/library/papers/4736831PubMed
114,796,647Isoelectric analysis of neonatal monofocal antibody.Immunochemistry1973https://conductscience.org/library/papers/4796647PubMed

Cited by10

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 45 citations.

PMIDTitleJournalYearIn PapersSource
22,859,976Characterization of immune responses induced by immunization with the HA DNA vaccines of two antigenically distinctive H5N1 HPAIV isolates.PLoS One2012https://conductscience.org/library/papers/22859976PubMed
4,139,234Antibody responses to antigenic determinants of influenza virus hemagglutinin. II. Original antigenic sin: a bone marrow-derived lymphocyte memory phenomenon modulated by thymus-derived lymphocytes.J Exp Med1974https://conductscience.org/library/papers/4139234PubMed
2,477,487Molecular analysis of original antigenic sin. I. Clonal selection, somatic mutation, and isotype switching during a memory B cell response.J Exp Med1989https://conductscience.org/library/papers/2477487PubMed
1,087,122The acquisition of b-cell competence and diversity.Am J Pathol1976https://conductscience.org/library/papers/1087122PubMed
1,086,883Allogeneic carrier-specific enhancement of hapten-specific secondary B-cell responses.J Exp Med1976https://conductscience.org/library/papers/1086883PubMed
416,167The diversity of the influenza-specific primary B-cell repertoire in BALB/c mice.J Exp Med1978https://conductscience.org/library/papers/416167PubMed
342,401Differential tolerance of thymus-independent and thymus-dependent antibody responses.Immunology1978https://conductscience.org/library/papers/342401PubMed
312,903
Production of auto-anti-idiotypic antibody during the normal immune response to TNP-ficoll. I. Occurrence in AKR/J and BALB/c mice of hapten-augmentable, anti-TNP plaque-forming cells and their accelerated appearance in recipients of immune spleen cells.
J Exp Med1979https://conductscience.org/library/papers/312903PubMed
69,006Cytotoxic T cells distinguish between trinitrophenyl- and dinitrophenyl-modified syngeneic cells.J Exp Med1977https://conductscience.org/library/papers/69006PubMed
47,895The characterization fo the B-cell repertoire specific for the 2,4-dinitrophenyl and 2,4,6-trinitrophenyl determinants in neonatal BALB/c mice.J Exp Med1975https://conductscience.org/library/papers/47895PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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