Paper · 47895

The characterization fo the B-cell repertoire specific for the 2,4-dinitrophenyl and 2,4,6-trinitrophenyl determinants in neonatal BALB/c mice.

Klinman NR and 1 other. J Exp Med, 1975. Cited by 140 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. The characterization fo the B-cell repertoire specific for the 2,4-dinitrophenyl and 2,4,6-trinitrophenyl determinants in neonatal BALB/c mice. Papers, record 47895. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/47895

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: The characterization fo the B-cell repertoire specific for the 2,4-dinitrophenyl and 2,4,6-trinitrophenyl determinants in neonatal BALB/c mice.; PubMed
Journal: J Exp Med; PubMed
Year: 1975; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/47895/; PubMed
DOI: https://doi.org/10.1084/jem.141.5.1133; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2189788/; PubMed
The journal: https://conductscience.org/library/journal-index/2985109R; PubMed
Citations, by iCite: 140; iCite
Relative citation ratio, by iCite: 2.84; iCite
Revised in PubMed: 2019-05-08; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Klinman NR	N R
2	Press JL	J L

Source PubMed

Topics22

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Animals, Newborn	Major topic
B-Lymphocytes	Major topic
Epitopes	Major topic
Mice, Inbred BALB C	Major topic
Nitrophenols	Major topic
Age Factors
Animals
Antibody Formation
Clone Cells
Dinitrophenols
Haptens
Hemocyanins
Immunogenetics
Immunoglobulin Fab Fragments
Immunoglobulin M
Iodine Radioisotopes
Isoelectric Focusing
Mice
Radioimmunoassay
Species Specificity
Spleen
gamma-Globulins

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References18

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	4,542,609	Enumeration and analysis of antibody-forming cell precursors in the neonatal mouse.	J Immunol	1973	https://conductscience.org/library/papers/4542609	PubMed
2	4,126,771	Overlap stimulation of primary and secondary B cells by cross-reacting determinants.	J Exp Med	1973	https://conductscience.org/library/papers/4126771	PubMed
3	4,796,647	Isoelectric analysis of neonatal monofocal antibody.	Immunochemistry	1973	https://conductscience.org/library/papers/4796647	PubMed
4	4,150,447	Clonal nature of the immune response to phosphorylcholine. II. Idiotypic specificity and binding characteristics of anti-phosphorylcholine antibodies.	J Immunol	1974	https://conductscience.org/library/papers/4150447	PubMed
5	4,136,036	Restricted clonal response to DNP in adult offspring of immunized mice: a maternal effect.	J Immunol	1974	https://conductscience.org/library/papers/4136036	PubMed
6	4,546,808	Frequency of hapten-specific B cells in neonatal and adult murine spleens.	Eur J Immunol	1974	https://conductscience.org/library/papers/4546808	PubMed
7	4,412,785	Development of humoral immunity in lethally irradiated mice reconstituted with fetal liver.	J Immunol	1974	https://conductscience.org/library/papers/4412785	PubMed
8	4,138,468	Ontogeny of B-lymphocyte function. I. Restricted heterogeneity of the antibody response of B lymphocytes from neonatal and fetal mice.	J Exp Med	1974	https://conductscience.org/library/papers/4138468	PubMed
9	45,858	Expression of specific clones during B cell development.	Fed Proc	1975	https://conductscience.org/library/papers/45858	PubMed
10	46,913	Heterogeneity of the BALB/c antiphosphorylcholine antibody response at the precursor cell level.	J Exp Med	1975	https://conductscience.org/library/papers/46913	PubMed

1 to 10 of 18

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Cited by37

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 140 citations.

PMID	Title	Journal	Year	In Papers	Source
35,892,708	Understanding and Modulating Antibody Fine Specificity: Lessons from Combinatorial Biology.	Antibodies (Basel)	2022	https://conductscience.org/library/papers/35892708	PubMed
10,852,106	Relative roles of somatic and Darwinian evolution in shaping the antibody response.	Immunol Res	2000	https://conductscience.org/library/papers/10852106	PubMed
6,974,133	Role of T cells in the development of memory B cells. Quantitative and qualitative analysis.	Immunology	1981	https://conductscience.org/library/papers/6974133	PubMed
6,969,889	Production of auto-anti-idiotypic antibody during the normal immune response: changes in the auto-anti-idiotypic antibody response and the idiotype repertoire associated with aging.	Proc Natl Acad Sci U S A	1980	https://conductscience.org/library/papers/6969889	PubMed
6,965,400	Susceptibility to in vitro tolerance induction of adult B cells from mice with an X-linked B-cell defect.	J Exp Med	1980	https://conductscience.org/library/papers/6965400	PubMed
6,965,399	Ontogenic development of B-lymphocyte function and tolerance susceptibility in vivo and in an in vitro organ culture system.	J Exp Med	1980	https://conductscience.org/library/papers/6965399	PubMed
6,601,176	Genetic and temporal control of neonatal antibody expression.	J Exp Med	1983	https://conductscience.org/library/papers/6601176	PubMed
6,359,323	Developmental aspects of B-cell repertoire phenotype.	Surv Immunol Res	1983	https://conductscience.org/library/papers/6359323	PubMed
6,223,111	Restricted adult clonal profiles induced by neonatal immunization. Influence of suppressor T cells.	J Exp Med	1983	https://conductscience.org/library/papers/6223111	PubMed
6,172,363	Defining the immune mechanism with monoclonal antibodies.	In Vitro	1981	https://conductscience.org/library/papers/6172363	PubMed

1 to 10 of 37

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Genes0

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None in this release.

Drugs0

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None in this release.

Data0

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None in this release.

Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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