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Paper · 41310366

Gut microbial β-glucuronidases and their role in the microbiome-metabolite axis in colorectal cancer.

Chen J and 4 others. Nat Commun, 2025. Cited by 4 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Gut microbial β-glucuronidases and their role in the microbiome-metabolite axis in colorectal cancer. Papers, record 41310366. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41310366

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Gut microbial β-glucuronidases and their role in the microbiome-metabolite axis in colorectal cancer.
PubMed
Journal
Nat Commun
PubMed
Year
2025
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
4
iCite
Revised in PubMed
2025-11-30
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Chen JJunruhttps://orcid.org/0009-0009-4417-4890
2Li YYan
3Tang SShuai
4Jin WWenyu
5Yan RRuhttps://orcid.org/0000-0001-6268-360X

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Colorectal NeoplasmsMajor topic
Gastrointestinal MicrobiomeMajor topic
GlucuronidaseMajor topic
Humans
HCT116 Cells
Female
Male
Biomarkers, Tumor
Middle Aged

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
MYRG-GRG2023-00241-ICMS-UMDFUniversidade de Macau (University of Macau)PubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References69

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
128,578,872An Atlas of β-Glucuronidases in the Human Intestinal Microbiome.Structure2017https://conductscience.org/library/papers/28578872PubMed
239,102,235Chemical Isotope Labeling and Dual-Filtering Strategy for Comprehensive Profiling of Urinary Glucuronide Conjugates.Anal Chem2024https://conductscience.org/library/papers/39102235PubMed
341,310,366Gut microbial β-glucuronidases and their role in the microbiome-metabolite axis in colorectal cancer.Nat Commun2025https://conductscience.org/library/papers/41310366PubMed
438,204,437Inhibition of Uridine 5'-diphospho-glucuronosyltransferases A10 and B7 by vitamins: insights from in silico and in vitro studies.In Silico Pharmacol2024https://conductscience.org/library/papers/38204437PubMed
534,606,537Sucralose enhances the susceptibility to dextran sulfate sodium (DSS) induced colitis in mice with changes in gut microbiota.Food Funct2021https://conductscience.org/library/papers/34606537PubMed
635,308,380β-Glucuronidase Pattern Predicted From Gut Metagenomes Indicates Potentially Diversified Pharmacomicrobiomics.Front Microbiol2022https://conductscience.org/library/papers/35308380PubMed
721,389,180High-protein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health.Am J Clin Nutr2011https://conductscience.org/library/papers/21389180PubMed
819,228,118The regulation of intestinal mucin MUC2 expression by short-chain fatty acids: implications for epithelial protection.Biochem J2009https://conductscience.org/library/papers/19228118PubMed
925,758,642Gut microbiome development along the colorectal adenoma-carcinoma sequence.Nat Commun2015https://conductscience.org/library/papers/25758642PubMed
1023,060,610CD-HIT: accelerated for clustering the next-generation sequencing data.Bioinformatics2012https://conductscience.org/library/papers/23060610PubMed

1 to 10 of 69

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Cited by3

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 4 citations.

PMIDTitleJournalYearIn PapersSource
42,326,837Associations between gut microbiome and 24-hour blood pressure variability: a cross-sectional study highlighting sex differences and potential therapeutic targets.Gut Microbiome (Camb)2026https://conductscience.org/library/papers/42326837PubMed
41,752,380β-Glucuronidase at the Microbiota-Host Interface: Dual Regulatory Roles and Precision Modulation by Natural Products.Molecules2026https://conductscience.org/library/papers/41752380PubMed
41,310,366Gut microbial β-glucuronidases and their role in the microbiome-metabolite axis in colorectal cancer.Nat Commun2025https://conductscience.org/library/papers/41310366PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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