Paper · 41369405

Extracellular Vesicles from iPSC-Derived Glial Progenitor Cells Prevent Glutamate-Induced Excitotoxicity by Stabilising Calcium Oscillations and Mitochondrial Depolarisation.

Shedenkova M and 15 others. Cells, 2025. Cited by 2 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Extracellular Vesicles from iPSC-Derived Glial Progenitor Cells Prevent Glutamate-Induced Excitotoxicity by Stabilising Calcium Oscillations and Mitochondrial Depolarisation. Papers, record 41369405. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41369405

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Extracellular Vesicles from iPSC-Derived Glial Progenitor Cells Prevent Glutamate-Induced Excitotoxicity by Stabilising Calcium Oscillations and Mitochondrial Depolarisation.; PubMed
Journal: Cells; PubMed
Year: 2025; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/41369405/; PubMed
DOI: https://doi.org/10.3390/cells14231915; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC12691032/; PubMed
The journal: https://conductscience.org/library/journal-index/101600052; PubMed
Citations, by iCite: 2; iCite
Revised in PubMed: 2026-09-25; PubMed

Authors16

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	ORCID iD
1	Shedenkova M	Margarita	https://orcid.org/0000-0001-7415-1520
2	Gurianova A	Anastasiia
3	Krasilnikova I	Irina	https://orcid.org/0000-0001-9453-3040
4	Sudina A	Anastasia	https://orcid.org/0000-0003-3531-7684
5	Karpulevich E	Evgeny	https://orcid.org/0000-0002-6771-2163
6	Maksimov Y	Yaroslav
7	Samburova M	Marina	https://orcid.org/0009-0002-6816-1719
8	Guguchkin E	Egor	https://orcid.org/0000-0001-7885-9892
9	Nefedova Z	Zlata
10	Babenko V	Valentina

1 to 10 of 16Source PubMed

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Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Glutamic Acid	Major topic
Induced Pluripotent Stem Cells	Major topic
Membrane Potential, Mitochondrial	Major topic
Extracellular Vesicles	Major topic
Neuroglia	Major topic
Calcium Signaling	Major topic
Humans
Phosphatidylinositol 3-Kinases
Calcium
Proto-Oncogene Proteins c-akt
Signal Transduction
Mitochondria
Cell Survival

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by
KBK 075 0110 47 2 U8 70440 621	Russian Ministry of Education and Science			PubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References300

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	36,291,443	SCN1B Genetic Variants: A Review of the Spectrum of Clinical Phenotypes and a Report of Early Myoclonic Encephalopathy.	Children (Basel)	2022	https://conductscience.org/library/papers/36291443	PubMed
2	14,570,283	Migration and differentiation of nuclear fluorescence-labeled bone marrow stromal cells after transplantation into cerebral infarct and spinal cord injury in mice.	Neuropathology	2003	https://conductscience.org/library/papers/14570283	PubMed
3	29,351,877	REST, a master transcriptional regulator in neurodegenerative disease.	Curr Opin Neurobiol	2018	https://conductscience.org/library/papers/29351877	PubMed
4	21,467,032	Transcriptional regulation of pro-apoptotic protein kinase Cdelta: implications for oxidative stress-induced neuronal cell death.	J Biol Chem	2011	https://conductscience.org/library/papers/21467032	PubMed
5	19,287,192	Bone morphogenetic protein 4 stimulates neuronal differentiation of neuronal stem cells through the ERK pathway.	Exp Mol Med	2009	https://conductscience.org/library/papers/19287192	PubMed
6	24,808,846	Genetic variation of the RASGRF1 regulatory region affects human hippocampus-dependent memory.	Front Hum Neurosci	2014	https://conductscience.org/library/papers/24808846	PubMed
7	19,953,094	Notch1 regulates the functional contribution of RhoC to cervical carcinoma progression.	Br J Cancer	2010	https://conductscience.org/library/papers/19953094	PubMed
8	33,946,667	Therapeutic Effects of hiPSC-Derived Glial and Neuronal Progenitor Cells-Conditioned Medium in Experimental Ischemic Stroke in Rats.	Int J Mol Sci	2021	https://conductscience.org/library/papers/33946667	PubMed
9	38,396,951	The Association of ADAMTS7 Gene Polymorphisms with the Risk of Coronary Artery Disease Occurrence and Cardiovascular Survival in the Polish Population: A Case-Control and a Prospective Cohort Study.	Int J Mol Sci	2024	https://conductscience.org/library/papers/38396951	PubMed
10	34,973,528	Identification of the Fosl1/AMPK/autophagy axis involved in apoptotic and inflammatory effects following spinal cord injury.	Int Immunopharmacol	2022	https://conductscience.org/library/papers/34973528	PubMed

1 to 10 of 300

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Cited by2

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 2 citations.

PMID	Title	Journal	Year	In Papers	Source
42,352,907	The Dual Role of Glial Extracellular Vesicles in Neurodegeneration: Insights from iPSC-Based Models.	Int J Mol Sci	2026	https://conductscience.org/library/papers/42352907	PubMed
42,121,878	The Use of Primary Spiral Ganglion Cells in Studying Glutamate Receptor Function and Excitotoxicity in the Cochlea.	Cells	2026	https://conductscience.org/library/papers/42121878	PubMed

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
AKT1	207	PubTator's text mining	https://conductscience.org/library/genes/207	NCBI Gene
PIK3CB	5,291	PubTator's text mining	https://conductscience.org/library/genes/5291	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data2

The data bank entries PubMed's record names. Trial numbers are under Trials.

Data bank	Accession	Source
GEO	GSE282138	GEO
GEO	GSE307721	GEO

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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