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Paper417018

Free light chain synthesis by neoplastic cells in chronic lymphocytic leukaemia and non-Hodgkin's lymphoma.

Gordon J and 2 others. Immunology, 1978. Cited by 56 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Free light chain synthesis by neoplastic cells in chronic lymphocytic leukaemia and non-Hodgkin's lymphoma. Papers, record 417018. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/417018

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Free light chain synthesis by neoplastic cells in chronic lymphocytic leukaemia and non-Hodgkin's lymphoma.
PubMed
Journal
Immunology
PubMed
Year
1978
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
56
iCite
Relative citation ratio, by iCite
1.69
iCite
Revised in PubMed
2018-11-13
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Gordon JJ
2Howlett ARA R
3Smith JLJ L

Source PubMed

Topics7

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Immunoglobulin Light ChainsMajor topic
Leukemia, LymphoidMajor topic
LymphomaMajor topic
B-Lymphocytes
Humans
In Vitro Techniques
Receptors, Antigen, B-Cell

Source PubMed

References19

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
113,917,083Further studies of the gamma-related proteins of normal urine.J Clin Invest1962https://conductscience.org/library/papers/13917083PubMed
2403,235Mitogen activation of human chronic lymphatic leukemia cells. I. Synthesis and secretion of immunoglobulin.J Immunol1977https://conductscience.org/library/papers/403235PubMed
3608,682Immunoglobulin expression and synthesis by human haemic cell lines.Immunology1977https://conductscience.org/library/papers/608682PubMed
44,172,069Relative rates of synthesis of immunoglobulins and light chains in rabbit spleen cells during secondary response.Nature1968https://conductscience.org/library/papers/4172069PubMed
54,589,993Occurrence of surface IgM, IgD, and free light chains of human lymphocytes.J Exp Med1974https://conductscience.org/library/papers/4589993PubMed
64,139,472B-cell neoplasia in man.Lancet1974https://conductscience.org/library/papers/4139472PubMed
74,163,635Light and heavy chain components of gamma globulins in urines of normal persons and patients with agammaglobulinemia.J Clin Invest1967https://conductscience.org/library/papers/4163635PubMed
84,182,787Urinary light chain excretion in leukaemia and lymphoma.Clin Exp Immunol1969https://conductscience.org/library/papers/4182787PubMed
91,084,241T and B lymphocytes and Reed-Sternberg cells in Hodgkin's disease lymph nodes and spleens.Clin Exp Immunol1976https://conductscience.org/library/papers/1084241PubMed
104,215,140The identification of mouse myeloma cells which have undergone mutations in immunoglobulin production.Soc Gen Physiol Ser1974https://conductscience.org/library/papers/4215140PubMed
114,577,736Opsonic adherence of sensitized ox red cells to human lymphocytes as measured by rosette formation.Int Arch Allergy Appl Immunol1973https://conductscience.org/library/papers/4577736PubMed
124,549,576B- and T-lymphocyte markers on transformed lymphocytes from mitogen-stimulated cultures of normal and CLL lymphocytes and on tonsil blasts.Clin Exp Immunol1974https://conductscience.org/library/papers/4549576PubMed
13816,582IgA and IgM cytoplastic inclusions in a series of cases of chronic lymphocytic leukaemia.Clin Exp Immunol1976https://conductscience.org/library/papers/816582PubMed
14810,881Free light chains of immunoglobulins in normal serum and urine determined by radioimmunoassay.Scand J Clin Lab Invest1975https://conductscience.org/library/papers/810881PubMed
151,103,381B-lymphocyte subpopulations in the mouse. Organ distribution and ontogeny of immunoglobulin-synthesizing and of mitogen-sensitive cells.Transplant Rev1975https://conductscience.org/library/papers/1103381PubMed
161,081,895B lymphocyte subpopulations in chronic lymphocytic leukemia.Blood1976https://conductscience.org/library/papers/1081895PubMed
171,254,967Cell membrane IgD: demonstration of IgD on human lymphocytes by enzyme-catalyzed iodination and comparison with cell surface Ig of mouse, guinea pig, and rabbit.J Immunol1976https://conductscience.org/library/papers/1254967PubMed
185,965,538Synthesis of excess light chains of gamma globulin by rabbit lymph node cells.Nature1966https://conductscience.org/library/papers/5965538PubMed
195,907,290Acrylamide-gel electrophorograms by mechanical fractionation: radioactive adenovirus proteins.Science1966https://conductscience.org/library/papers/5907290PubMed

Cited by16

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 56 citations.

PMIDTitleJournalYearIn PapersSource
28,497,093Association between abnormal serum free light chains ratio and known prognostic factors in lymphoma; a nephrology viewpoint.J Renal Inj Prev2017https://conductscience.org/library/papers/28497093PubMed
21,765,023Monoclonal and polyclonal serum free light chains and clinical outcome in chronic lymphocytic leukemia.Blood2011https://conductscience.org/library/papers/21765023PubMed
9,486,419Differences in kappa to lambda (kappa:lambda) ratios of serum and urinary free light chains.Clin Exp Immunol1998https://conductscience.org/library/papers/9486419PubMed
7,400,356Immunoglobulin synthesis by neoplastic cells: models of a clonal transition from IgM to IgG synthesis.J Clin Pathol1980https://conductscience.org/library/papers/7400356PubMed
6,969,771Extracellular idiotypic immunoglobulin arising from human leukemic B lymphocytes.J Exp Med1980https://conductscience.org/library/papers/6969771PubMed
6,817,774Correlation between Ig-synthesis patterns and lymphoma classification.Br J Cancer1982https://conductscience.org/library/papers/6817774PubMed
6,802,538Reactive and neoplastic human lymphoid cells producing J chain in the absence of immunoglobulin: evidence for the existence of 'J chain disease'?Clin Exp Immunol1981https://conductscience.org/library/papers/6802538PubMed
6,788,682Free immunoglobulin light chain synthesis by human foetal liver and cord blood lymphocytes.Immunology1981https://conductscience.org/library/papers/6788682PubMed
6,775,652Monoclonal immunoglobulin light chains in urine of patients with lymphoma.Br J Cancer1980https://conductscience.org/library/papers/6775652PubMed
6,437,429Immunoglobulin negative follicle centre cell lymphoma.Br J Cancer1984https://conductscience.org/library/papers/6437429PubMed
6,405,775Monoclonal immunoglobulin light chain in urine of patients with B lymphocytic disease: its source and use as a diagnostic aid.Br J Cancer1983https://conductscience.org/library/papers/6405775PubMed
6,190,595Detection of free kappa chains in human serum and urine using pairs of monoclonal antibodies reacting with C kappa epitopes not available on whole immunoglobulins.Clin Exp Immunol1983https://conductscience.org/library/papers/6190595PubMed
3,082,300Urinary monoclonal free light chains in primary Sjögren's syndrome: an aid to the diagnosis of malignant lymphoma.Ann Rheum Dis1986https://conductscience.org/library/papers/3082300PubMed
466,856Histochemical studies for 5'-nucleotidase and alpha-naphthyl (non-specific) esterase in lymphocytes from patients with primary immunoglobulin deficiencies.Clin Exp Immunol1979https://conductscience.org/library/papers/466856PubMed
107,201Biosynthesis and characterisation of IgMlambda in a case of chronic lymphocytic leukaemia with intracellular immunoglobulin inclusions.J Clin Pathol1979https://conductscience.org/library/papers/107201PubMed
104,817Free immunoglobulin light chain synthesis by lymphocytes from patients with hypogammaglobulinaemia.Clin Exp Immunol1978https://conductscience.org/library/papers/104817PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
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  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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