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Paper403235

Mitogen activation of human chronic lymphatic leukemia cells. I. Synthesis and secretion of immunoglobulin.

Maino VC and 3 others. J Immunol, 1977. Cited by 68 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Mitogen activation of human chronic lymphatic leukemia cells. I. Synthesis and secretion of immunoglobulin. Papers, record 403235. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/403235

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Mitogen activation of human chronic lymphatic leukemia cells. I. Synthesis and secretion of immunoglobulin.
PubMed
Journal
J Immunol
PubMed
Year
1977
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
68
iCite
Relative citation ratio, by iCite
1.89
iCite
Revised in PubMed
2007-11-15
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Maino VCV C
2Kurnick JTJ T
3Kubo RTR T
4Grey HMH M

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Immunoglobulin Light ChainsMajor topic
Leukemia, LymphoidMajor topic
MitogensMajor topic
Receptors, Antigen, B-CellMajor topic
B-Lymphocytes
Concanavalin A
Electrophoresis, Polyacrylamide Gel
Humans
Lectins
Lymphocyte Activation

Source PubMed

Cited by17

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 68 citations.

PMIDTitleJournalYearIn PapersSource
21,765,023Monoclonal and polyclonal serum free light chains and clinical outcome in chronic lymphocytic leukemia.Blood2011https://conductscience.org/library/papers/21765023PubMed
10,821,464Urine free light chains in SLE: clonal markers of B-cell activity and potential link to in vivo secreted Ig.J Clin Immunol2000https://conductscience.org/library/papers/10821464PubMed
6,979,444The roles of leukaemic and residual normal cells in the proliferative response of chronic lymphocytic leukaemic lymphocytes to mitogens.Clin Exp Immunol1982https://conductscience.org/library/papers/6979444PubMed
6,970,751Chronic lymphocytic leukemia cells lack the 185,000-dalton macromolecular insoluble cold globulin present on normal B lymphocytes.J Clin Invest1981https://conductscience.org/library/papers/6970751PubMed
6,812,054Mediators from cloned T helper cell lines affect immunoglobulin expression by B cells.Proc Natl Acad Sci U S A1982https://conductscience.org/library/papers/6812054PubMed
6,805,990Mitogen-stimulated immunoglobulin production by chronic lymphocytic leukaemic lymphocytes.Clin Exp Immunol1982https://conductscience.org/library/papers/6805990PubMed
6,775,652Monoclonal immunoglobulin light chains in urine of patients with lymphoma.Br J Cancer1980https://conductscience.org/library/papers/6775652PubMed
6,405,775Monoclonal immunoglobulin light chain in urine of patients with B lymphocytic disease: its source and use as a diagnostic aid.Br J Cancer1983https://conductscience.org/library/papers/6405775PubMed
3,872,753Phorbol ester-induced differentiation of chronic B lymphocytic leukaemia cells--regulatory impact of autologous and allogeneic accessory cells.Clin Exp Immunol1985https://conductscience.org/library/papers/3872753PubMed
519,218Cell surface markers in chronic lymphatic leukaemia.Br Med J1979https://conductscience.org/library/papers/519218PubMed
417,885Free immunoglobulin light chain synthesis by neoplastic cells in leukaemic reticuloendotheliosis.Clin Exp Immunol1978https://conductscience.org/library/papers/417885PubMed
417,018Free light chain synthesis by neoplastic cells in chronic lymphocytic leukaemia and non-Hodgkin's lymphoma.Immunology1978https://conductscience.org/library/papers/417018PubMed
311,476Induction of amplified synthesis and secretion of IgM by fusion of murine 'b lymphoma with myeloma cells.Proc Natl Acad Sci U S A1979https://conductscience.org/library/papers/311476PubMed
309,923Induction of in vitro differentiation and immunoglobulin synthesis of human leukemic B lymphocytes.J Exp Med1978https://conductscience.org/library/papers/309923PubMed
107,201Biosynthesis and characterisation of IgMlambda in a case of chronic lymphocytic leukaemia with intracellular immunoglobulin inclusions.J Clin Pathol1979https://conductscience.org/library/papers/107201PubMed
104,817Free immunoglobulin light chain synthesis by lymphocytes from patients with hypogammaglobulinaemia.Clin Exp Immunol1978https://conductscience.org/library/papers/104817PubMed
96,010Further studies of immunoglobulin synthesis by guinea pig leukaemic lymphocytes.Immunology1978https://conductscience.org/library/papers/96010PubMed

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
LBR3,930PubTator's text mininghttps://conductscience.org/library/genes/3930

Source NCBI Gene

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • References
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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