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Paper4210076

The pancreatic beta-cell recognition of insulin secretagogues. Comparisons of glucose with glyceraldehyde isomers and dihydroxyacetone.

Hellman B and 4 others. Arch Biochem Biophys, 1974. Cited by 114 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. The pancreatic beta-cell recognition of insulin secretagogues. Comparisons of glucose with glyceraldehyde isomers and dihydroxyacetone. Papers, record 4210076. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4210076

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The pancreatic beta-cell recognition of insulin secretagogues. Comparisons of glucose with glyceraldehyde isomers and dihydroxyacetone.
PubMed
Journal
Arch Biochem Biophys
PubMed
Year
1974
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
114
iCite
Relative citation ratio, by iCite
3.74
iCite
Revised in PubMed
2019-06-29
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Hellman BB
2Idahl LAL A
3Lernmark AA
4Sehlin JJ
5Täljedal IBI B

Source PubMed

Topics23

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
AcetoneMajor topic
GlucoseMajor topic
GlyceraldehydeMajor topic
InsulinMajor topic
Islets of LangerhansMajor topic
Animals
Arginine
Calcium
Carbon Radioisotopes
Dinitrophenols
Epinephrine
Female
Glucosamine
Glyburide
Insulin Secretion
Iodoacetates
Isomerism
Leucine
Male
Obesity
Phlorhizin
Theophylline
Time Factors

Source PubMed

Cited by27

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 114 citations.

PMIDTitleJournalYearIn PapersSource
39,854,399Islet NO-Synthases, extracellular NO and glucose-stimulated insulin secretion: Possible impact of neuronal NO-Synthase on the pentose phosphate pathway.PLoS One2025https://conductscience.org/library/papers/39854399PubMed
23,604,550Functional differences between aggregated and dispersed insulin-producing cells.Diabetologia2013https://conductscience.org/library/papers/23604550PubMed
8,446,591Glucose sensing in pancreatic islet beta cells: the key role of glucokinase and the glycolytic intermediates.Proc Natl Acad Sci U S A1993https://conductscience.org/library/papers/8446591PubMed
8,386,682Glucokinase and candidate genes for type 2 (non-insulin-dependent) diabetes mellitus.Diabetologia1993https://conductscience.org/library/papers/8386682PubMed
7,998,948A possible role for glyceraldehyde transport in the stimulation of HIT-T15 insulinoma cells.Biochem J1994https://conductscience.org/library/papers/7998948PubMed
7,646,447The stimulation of insulin secretion by D-glyceraldehyde correlates with its rate of oxidation in islet cells.Biochem J1995https://conductscience.org/library/papers/7646447PubMed
7,492,326Glycerol 3-phosphate-induced ATP production in intact mitochondria from pancreatic B-cells.Biochem J1995https://conductscience.org/library/papers/7492326PubMed
6,998,814Insulin release from human pancreatic islets in vitro.Diabetologia1980https://conductscience.org/library/papers/6998814PubMed
6,349,618Abnormal glucose metabolism accompanies failure of glucose to stimulate insulin release from a rat pancreatic cell line (RINm5F).Biochem J1983https://conductscience.org/library/papers/6349618PubMed
6,245,006Glucoreceptor mechanisms and the control of insulin release and biosynthesis.Diabetologia1980https://conductscience.org/library/papers/6245006PubMed
3,527,842Gestational hyperglycaemia and insulin release by the fetal rat pancreas in vitro: effect of amino acids and glyceraldehyde.Diabetologia1986https://conductscience.org/library/papers/3527842PubMed
2,442,195B cell insensitivity in a rat model of non-insulin-dependent diabetes. Evidence for a rapidly reversible effect of previous hyperglycemia.J Clin Invest1987https://conductscience.org/library/papers/2442195PubMed
1,205,021The effects of glucose, N-acetylglucosamine, glyceraldehyde and other sugars on insulin release in vivo.Diabetologia1975https://conductscience.org/library/papers/1205021PubMed
1,107,124Influence of anoxia on glucose metabolism in pancreatic islets: lack of correlation between fructose-1,6-diphosphate and apparent glycolytic flux.Diabetologia1975https://conductscience.org/library/papers/1107124PubMed
800,922The stimulus-secretion coupling of glucose-induced insulin release. XXII. Qualitative and quantitative aspects of glycolysis in isolated islets.Acta Diabetol Lat1976https://conductscience.org/library/papers/800922PubMed
789,164The inhibition of insulin secretion from the perfused rat pancreas after thyroxine treatment.Diabetologia1976https://conductscience.org/library/papers/789164PubMed
389,723Beta-cell recognition of stereoisomers of D-glucose.Diabetologia1979https://conductscience.org/library/papers/389723PubMed
384,996Metabolism and insulin-releasing capabilities of glucosamine and N-acetylglucosamine in isolated rat islets.Biochem J1979https://conductscience.org/library/papers/384996PubMed
365,176Stimulation of proinsulin biosynthesis and insulin release by pyruvate and lactate.Biochem J1978https://conductscience.org/library/papers/365176PubMed
365,173Protection of the pancreatic beta-cell glucoreceptor mechanism for insulin secretion during culture in chemically defined medium.Biochem J1978https://conductscience.org/library/papers/365173PubMed

See all 27 cited by

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
INS3,630PubTator's text mininghttps://conductscience.org/library/genes/3630

Source NCBI Gene

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

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  • Comments and corrections
  • References
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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