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Paper · 42858645

A mature tertiary lymphoid structure-associated spatial niche is inversely associated with ACC1-related lipid metabolism in neoadjuvant-treated hepatocellular carcinoma.

Wang R and 6 others. Transl Oncol, 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. A mature tertiary lymphoid structure-associated spatial niche is inversely associated with ACC1-related lipid metabolism in neoadjuvant-treated hepatocellular carcinoma. Papers, record 42858645. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42858645

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PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
A mature tertiary lymphoid structure-associated spatial niche is inversely associated with ACC1-related lipid metabolism in neoadjuvant-treated hepatocellular carcinoma.
Journal
Transl Oncol
Year
2026
Publication types
Journal Article
Revised in PubMed
2026-10-22

Source PubMed

Authors7

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Wang RRonghua
2Shen BBiao
3Wu YYanan
4Zhao SShuai
5Xu WWenhao
6Liu WWangrui
7Wang JJian

Source PubMed

Topics0

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None in this release.

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Trials0

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Comments and corrections0

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References58

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
125,282,359De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.Nat Med2014https://conductscience.org/library/papers/25282359PubMed
240,607,252Interferon Regulatory Factor 4 Recruits Immature B Cells to Signal Tertiary Lymphoid Structure Immaturity and Progression of Clear Cell Renal Cell Carcinoma.Int J Biol Sci2025https://conductscience.org/library/papers/40607252PubMed
338,773,347Glycolytic enzyme PFKL governs lipolysis by promoting lipid droplet-mitochondria tethering to enhance β-oxidation and tumor cell proliferation.Nat Metab2024https://conductscience.org/library/papers/38773347PubMed
432,066,950Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis.Nat Immunol2020https://conductscience.org/library/papers/32066950PubMed
542,566,529APOE+ macrophages and POSTN+CAFs form immune-exclusion niche driving immunotherapy resistance in clear-cell renal carcinoma.Sci Adv2026https://conductscience.org/library/papers/42566529PubMed
641,495,164Integrative single-cell and spatial transcriptomics with explainable AI reveal lethal prognostic axis in prostate cancer.NPJ Digit Med2026https://conductscience.org/library/papers/41495164PubMed
735,933,472A single-cell atlas of the multicellular ecosystem of primary and metastatic hepatocellular carcinoma.Nat Commun2022https://conductscience.org/library/papers/35933472PubMed
842,207,882Pan-cancer spatial atlas of tertiary lymphoid structures.Science2026https://conductscience.org/library/papers/42207882PubMed
940,814,445Decoding the tumor microenvironment: insights into immunotherapy and beyond.J Natl Cancer Cent2025https://conductscience.org/library/papers/40814445PubMed
1040,185,093Spatial transcriptomics reveals tryptophan metabolism restricting maturation of intratumoral tertiary lymphoid structures.Cancer Cell2025https://conductscience.org/library/papers/40185093PubMed

Cited by0

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Genes0

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None in this release.

Drugs0

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None in this release.

Data0

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None in this release.

Data dates

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PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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