Paper · 42897482
Coordinated upregulation of Hippo, NF-κB and interferon pathway genes in pancreatic ductal adenocarcinoma: a retrospective tissue qRT-PCR profiling study with external tumour-versus-non-tumour validation, molecular subtype and survival analyses.
Balkan E and 7 others. BMC Gastroenterol, 2026.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Coordinated upregulation of Hippo, NF-κB and interferon pathway genes in pancreatic ductal adenocarcinoma: a retrospective tissue qRT-PCR profiling study with external tumour-versus-non-tumour validation, molecular subtype and survival analyses. Papers, record 42897482. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42897482
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
Coordinated upregulation of Hippo, NF-κB and interferon pathway genes in pancreatic ductal adenocarcinoma: a retrospective tissue qRT-PCR profiling study with external tumour-versus-non-tumour validation, molecular subtype and survival analyses.
- Journal
- BMC Gastroenterol
- Year
- 2026
- Publication types
- Journal Article
- Revised in PubMed
- 2026-10-22
Source PubMed
Topics27
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Pancreatic Neoplasms | Major topic |
| Carcinoma, Pancreatic Ductal | Major topic |
| NF-kappa B | Major topic |
| Protein Serine-Threonine Kinases | Major topic |
| Interferons | Major topic |
| Humans | |
| Retrospective Studies | |
| Female | |
| Male | |
| Up-Regulation | |
| Hippo Signaling Pathway | |
| Signal Transduction | |
| Transcription Factors | |
| Nuclear Proteins | |
| Gene Expression Regulation, Neoplastic | |
| Middle Aged | |
| Aged | |
| Adaptor Proteins, Signal Transducing | |
| Real-Time Polymerase Chain Reaction | |
| DNA-Binding Proteins | |
| RNA, Messenger | |
| Survival Analysis | |
| YAP-Signaling Proteins | |
| TEA Domain Transcription Factors | |
| Gene Expression Profiling | |
| Phosphoproteins | |
| ROC Curve |
Source PubMed
Grants1
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by |
|---|---|---|---|---|
| 2025 | Atatürk Üniversitesi | PubMed |
Source PubMed
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References32
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 25,731,159 | A gp130-Src-YAP module links inflammation to epithelial regeneration. | Nature | 2015 | https://conductscience.org/library/papers/25731159 | PubMed |
| 2 | 19,246,619 | The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. | Clin Chem | 2009 | https://conductscience.org/library/papers/19246619 | PubMed |
| 3 | 25,368,022 | ISG15 is a critical microenvironmental factor for pancreatic cancer stem cells. | Cancer Res | 2014 | https://conductscience.org/library/papers/25368022 | PubMed |
| 4 | 40,922,300 | Dickkopf-1 and cytoskeletal protein 4 mRNA expression associated with liver and kidney transplant rejection: Prospective observational study. | Medicine (Baltimore) | 2025 | https://conductscience.org/library/papers/40922300 | PubMed |
| 5 | 28,346,439 | Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade. | Nat Cell Biol | 2017 | https://conductscience.org/library/papers/28346439 | PubMed |
| 6 | 32,593,337 | Pancreatic cancer. | Lancet | 2020 | https://conductscience.org/library/papers/32593337 | PubMed |
| 7 | 40,572,763 | Molecular Crosstalk Between SIRT1, Wnt/β-Catenin Signaling, and Inflammatory Pathways in Renal Transplant Rejection: Role of miRNAs, lncRNAs, IL-1, IL-6, and Tubulointerstitial Inflammation. | Medicina (Kaunas) | 2025 | https://conductscience.org/library/papers/40572763 | PubMed |
| 8 | 32,200,350 | Repression of the Type I Interferon Pathway Underlies MYC- and KRAS-Dependent Evasion of NK and B Cells in Pancreatic Ductal Adenocarcinoma. | Cancer Discov | 2020 | https://conductscience.org/library/papers/32200350 | PubMed |
| 9 | 11,846,609 | Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. | Methods | 2001 | https://conductscience.org/library/papers/11846609 | PubMed |
| 10 | 24,911,653 | An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation. | Biochem J | 2014 | https://conductscience.org/library/papers/24911653 | PubMed |
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Drugs0
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Data0
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Data dates
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- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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