Paper · 42909040

Acarbose differentially affects gut microbial metabolism of maltose and sucrose, distinctly modulating host metabolism.

Yoshikawa H and 10 others. iScience, 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Acarbose differentially affects gut microbial metabolism of maltose and sucrose, distinctly modulating host metabolism. Papers, record 42909040. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42909040

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Paper

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Title: Acarbose differentially affects gut microbial metabolism of maltose and sucrose, distinctly modulating host metabolism.
Journal: iScience
Year: 2026
Publication types: Journal Article
PubMed: https://pubmed.ncbi.nlm.nih.gov/42909040/
DOI: https://doi.org/10.1016/j.isci.2026.117889
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC13683718/
The journal: https://conductscience.org/library/journal-index/101724038
Revised in PubMed: 2026-10-24

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Authors11

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Yoshikawa H	Hayato
2	Lee E	Eunyoung
3	Hatano R	Ryo
4	Taki Y	Yuki
5	Takaya A	Akiko
6	Eguchi A	Akifumi
7	Goto Y	Yoshiyuki
8	Miyamoto J	Junki
9	Kimura I	Ikuo
10	Tanaka T	Tomoaki

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Topics0

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Trials0

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References70

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	31,195,972	Changes in the gut microbiome and fermentation products concurrent with enhanced longevity in acarbose-treated mice.	BMC Microbiol	2019	https://conductscience.org/library/papers/31195972	PubMed
2	31,332,064	Metabolomics of Escherichia coli Treated with the Antimicrobial Carbon Monoxide-Releasing Molecule CORM-3 Reveals Tricarboxylic Acid Cycle as Major Target.	Antimicrob Agents Chemother	2019	https://conductscience.org/library/papers/31332064	PubMed
3	37,311,282	Immunological mechanisms of inflammatory diseases caused by gut microbiota dysbiosis: A review.	Biomed Pharmacother	2023	https://conductscience.org/library/papers/37311282	PubMed
4	19,542,131	Parasutterella excrementihominis gen. nov., sp. nov., a member of the family Alcaligenaceae isolated from human faeces.	Int J Syst Evol Microbiol	2009	https://conductscience.org/library/papers/19542131	PubMed
5	31,729,425	Sucrose intake lowers μ-opioid and dopamine D2/3 receptor availability in porcine brain.	Sci Rep	2019	https://conductscience.org/library/papers/31729425	PubMed
6	35,841,764	Phloretin suppresses carbohydrate-induced GLP-1 secretion via inhibiting short chain fatty acid release from gut microbiome.	Biochem Biophys Res Commun	2022	https://conductscience.org/library/papers/35841764	PubMed
7	27,259,147	From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites.	Cell	2016	https://conductscience.org/library/papers/27259147	PubMed
8	24,843,559	Glucagon-like peptide-1 secretion by direct stimulation of L cells with luminal sugar vs non-nutritive sweetener.	J Diabetes Investig	2012	https://conductscience.org/library/papers/24843559	PubMed
9	24,009,397	Gut microbiota from twins discordant for obesity modulate metabolism in mice.	Science	2013	https://conductscience.org/library/papers/24009397	PubMed
10	10,931,321	Structure and function of bacterial outer membrane proteins: barrels in a nutshell.	Mol Microbiol	2000	https://conductscience.org/library/papers/10931321	PubMed

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Cited by0

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Genes0

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Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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