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Paper · 42945313

Imaging [18F]FDG PET/CT pilot study of nicotinic acetylcholinergic receptor α2 knock-out mice and α2 hypersensitive mice compared to control mice: Male-female differences and nicotine effects.

Liang C and 8 others. PLoS One, 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Imaging [18F]FDG PET/CT pilot study of nicotinic acetylcholinergic receptor α2 knock-out mice and α2 hypersensitive mice compared to control mice: Male-female differences and nicotine effects. Papers, record 42945313. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42945313

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Imaging [18F]FDG PET/CT pilot study of nicotinic acetylcholinergic receptor α2 knock-out mice and α2 hypersensitive mice compared to control mice: Male-female differences and nicotine effects.
Journal
PLoS One
Year
2026
Publication types
Journal Article
Revised in PubMed
2026-11-03

Source PubMed

Authors9

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Liang CChristopherhttps://orcid.org/0000-0001-9081-294X
2Tucker TETitus E
3Coronel ADLAshlee D Lhttps://orcid.org/0009-0003-2810-766X
4Nguyen EHNEllen H N
5Nguyen JLJanet Lhttps://orcid.org/0009-0006-1295-2238
6Intskirveli IIrakli
7Lazar RRonit
8Metherate RRaju
9Mukherjee JJogeshwarhttps://orcid.org/0000-0003-1009-877X

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Fluorodeoxyglucose F18Major topic
NicotineMajor topic
Receptors, NicotinicMajor topic
Positron Emission Tomography Computed TomographyMajor topic
Animals
Female
Male
Mice
Mice, Knockout
Pilot Projects
Brain
Sex Factors

Source PubMed

Grants5

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
R01 AG029479NIA NIH HHSUnited StatesR01AG029479PubMedNIH RePORTER
RF1 AG029479NIA NIH HHSUnited StatesRF1AG029479PubMedNIH RePORTER
R01 DC017687NIDCD NIH HHSUnited StatesR01DC017687PubMedNIH RePORTER
R01 AG067073NIA NIH HHSUnited StatesR01AG067073PubMedNIH RePORTER
R01 AG077700NIA NIH HHSUnited StatesR01AG077700PubMedNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections1

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

KindPMIDTitleIn Papers
Update of41,929,019Imaging [18F]FDG PET/CT Study of Nicotinic Acetylcholinergic Receptor α2 Knock-Out Mice and α2 Hypersensitive Mice Compared to Control Mice: Male-Female Differences and Nicotine Effects.https://conductscience.org/library/papers/41929019

Source PubMed

References67

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
141,065,327Neurons in Need: Glucose, but Not Lactate, Is Required to Support Energy-Demanding Synaptic Transmission.J Neurochem2025https://conductscience.org/library/papers/41065327PubMed
234,901,060Quantitative Brain Positron Emission Tomography in Female 5XFAD Alzheimer Mice: Pathological Features and Sex-Specific Alterations.Front Med (Lausanne)2021https://conductscience.org/library/papers/34901060PubMed
312,655,323Intravenous nicotine reduces cerebral glucose metabolism: a preliminary study.Neuropsychopharmacology2003https://conductscience.org/library/papers/12655323PubMed
426,317,527Effects of Estrogens on Adipokines and Glucose Homeostasis in Female Aromatase Knockout Mice.PLoS One2015https://conductscience.org/library/papers/26317527PubMed
517,504,863Effect of nicotine and ephedrine on the accumulation of 18F-FDG in brown adipose tissue.J Nucl Med2007https://conductscience.org/library/papers/17504863PubMed
639,233,590Effects of Nicotine Doses and Administration Frequencies on Mouse Body Weight and Adipose Tissues.Nicotine Tob Res2025https://conductscience.org/library/papers/39233590PubMed
737,652,281The alpha2 nicotinic acetylcholine receptor, a subunit with unique and selective expression in inhibitory interneurons associated with principal cells.Pharmacol Res2023https://conductscience.org/library/papers/37652281PubMed
835,883,660Organ-Specific Glucose Uptake: Does Sex Matter?Cells2022https://conductscience.org/library/papers/35883660PubMed
939,332,748Astroglial glucose uptake determines brain FDG-PET alterations and metabolic connectivity during healthy aging in mice.Neuroimage2024https://conductscience.org/library/papers/39332748PubMed
1039,826,824Neurobiological mechanisms of nicotine's effects on feeding and body weight.Neurosci Biobehav Rev2025https://conductscience.org/library/papers/39826824PubMed

Cited by0

The papers in our copy of PubMed whose reference list names this one, newest first.

None in this release.

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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