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Paper · 42948748

Emerging insights into PPARα's role in lean metabolic dysfunction-associated steatotic liver disease: Implications for targeted therapies.

Yang Y and 8 others. Acta Pharm Sin B, 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Emerging insights into PPARα's role in lean metabolic dysfunction-associated steatotic liver disease: Implications for targeted therapies. Papers, record 42948748. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42948748

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Emerging insights into PPARα's role in lean metabolic dysfunction-associated steatotic liver disease: Implications for targeted therapies.
Journal
Acta Pharm Sin B
Year
2026
Publication types
Journal Article, Review
Revised in PubMed
2026-10-29

Source PubMed

Authors9

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Yang YYafei
2Zhang FFurong
3Peng ZZhuang
4Wu YYafei
5Li LLing
6Shen ZZixia
7Ye QQifa
8Yue JJiang
9Na SShufang

Source PubMed

Topics0

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None in this release.

Grants0

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None in this release.

Trials0

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None in this release.

Comments and corrections0

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References469

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
138,280,375Gut-liver axis calibrates intestinal stem cell fitness.Cell2024https://conductscience.org/library/papers/38280375PubMed
219,356,714Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation.Cell Metab2009https://conductscience.org/library/papers/19356714PubMed
318,930,334Dietary resveratrol alters lipid metabolism-related gene expression of mice on an atherogenic diet.J Hepatol2008https://conductscience.org/library/papers/18930334PubMed
425,102,981Expression of liver X receptor correlates with intrahepatic inflammation and fibrosis in patients with nonalcoholic fatty liver disease.Dig Dis Sci2014https://conductscience.org/library/papers/25102981PubMed
535,842,425Loss of immunity-related GTPase GM4951 leads to nonalcoholic fatty liver disease without obesity.Nat Commun2022https://conductscience.org/library/papers/35842425PubMed
628,287,408Nutrient-sensing nuclear receptors PPARα and FXR control liver energy balance.J Clin Invest2017https://conductscience.org/library/papers/28287408PubMed
721,115,502Sirt1 acts in association with PPARα to protect the heart from hypertrophy, metabolic dysregulation, and inflammation.Cardiovasc Res2011https://conductscience.org/library/papers/21115502PubMed
826,679,678Icariin attenuates cerebral ischemia-reperfusion injury through inhibition of inflammatory response mediated by NF-κB, PPARα and PPARγ in rats.Int Immunopharmacol2016https://conductscience.org/library/papers/26679678PubMed
927,207,553A Novel Function of Hepatic FOG2 in Insulin Sensitivity and Lipid Metabolism Through PPARα.Diabetes2016https://conductscience.org/library/papers/27207553PubMed
1032,012,316Inadequate Physical Activity and Sedentary Behavior Are Independent Predictors of Nonalcoholic Fatty Liver Disease.Hepatology2020https://conductscience.org/library/papers/32012316PubMed

Cited by0

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None in this release.

Genes0

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None in this release.

Drugs0

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None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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