Paper · 42959152

Isolated TERT promoter mutation may define a high-risk prognostic subgroup in papillary thyroid carcinoma: an exploratory, hypothesis-generating analysis of TCGA and GSE33630 datasets.

Guan B and 5 others. Front Endocrinol (Lausanne), 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Isolated TERT promoter mutation may define a high-risk prognostic subgroup in papillary thyroid carcinoma: an exploratory, hypothesis-generating analysis of TCGA and GSE33630 datasets. Papers, record 42959152. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42959152

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Paper

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Title: Isolated TERT promoter mutation may define a high-risk prognostic subgroup in papillary thyroid carcinoma: an exploratory, hypothesis-generating analysis of TCGA and GSE33630 datasets.
Journal: Front Endocrinol (Lausanne)
Year: 2026
Publication types: Journal Article
PubMed: https://pubmed.ncbi.nlm.nih.gov/42959152/
DOI: https://doi.org/10.3389/fendo.2026.1881969
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC13716624/
The journal: https://conductscience.org/library/journal-index/101555782
Revised in PubMed: 2026-10-31

Source PubMed

Authors6

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Guan B	Bing
2	Zhou R	Rong
3	Zhang S	Sijia
4	Chen Y	Yawen
5	Li L	Lulu
6	He P	Ping

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Thyroid Neoplasms	Major topic
Thyroid Cancer, Papillary	Major topic
Telomerase	Major topic
Promoter Regions, Genetic	Major topic
Mutation	Major topic
Biomarkers, Tumor	Major topic
Humans
Prognosis
Female
Proto-Oncogene Proteins B-raf
Male
Middle Aged
Adult

Source PubMed

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References20

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	23,766,237	Highly prevalent TERT promoter mutations in aggressive thyroid cancers.	Endocr Relat Cancer	2013	https://conductscience.org/library/papers/23766237	PubMed
2	33,012,268	BRAFV600E Overrides NOTCH Signaling in Thyroid Cancer.	Thyroid	2021	https://conductscience.org/library/papers/33012268	PubMed
3	24,910,204	PCDH20 functions as a tumour-suppressor gene through antagonizing the Wnt/β-catenin signalling pathway in hepatocellular carcinoma.	J Viral Hepat	2015	https://conductscience.org/library/papers/24910204	PubMed
4	16,651,412	Frequent silencing of the candidate tumor suppressor PCDH20 by epigenetic mechanism in non-small-cell lung cancers.	Cancer Res	2006	https://conductscience.org/library/papers/16651412	PubMed
5	26,733,501	TERT promoter mutations in thyroid cancer.	Endocr Relat Cancer	2016	https://conductscience.org/library/papers/26733501	PubMed
6	19,685,283	Cancer Cells Expressing Toll-like Receptors and the Tumor Microenvironment.	Cancer Microenviron	2009	https://conductscience.org/library/papers/19685283	PubMed
7	29,625,055	An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics.	Cell	2018	https://conductscience.org/library/papers/29625055	PubMed
8	36,633,525	Cancer statistics, 2023.	CA Cancer J Clin	2023	https://conductscience.org/library/papers/36633525	PubMed
9	34,422,995	DAPK2 activates NF-κB through autophagy-dependent degradation of I-κBα during thyroid cancer development and progression.	Ann Transl Med	2021	https://conductscience.org/library/papers/34422995	PubMed
10	23,348,506	Highly recurrent TERT promoter mutations in human melanoma.	Science	2013	https://conductscience.org/library/papers/23348506	PubMed

1 to 10 of 20

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Cited by0

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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HGNCCC0: https://www.genenames.org/about/license/
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NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
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