Paper · 23766237

Highly prevalent TERT promoter mutations in aggressive thyroid cancers.

Liu X and 8 others. Endocr Relat Cancer, 2013. Cited by 516 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Highly prevalent TERT promoter mutations in aggressive thyroid cancers. Papers, record 23766237. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/23766237

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Highly prevalent TERT promoter mutations in aggressive thyroid cancers.; PubMed
Journal: Endocr Relat Cancer; PubMed
Year: 2013; PubMed
Publication types: Journal Article, Research Support, N.I.H., Extramural; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/23766237/; PubMed
DOI: https://doi.org/10.1530/erc-13-0210; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC3782569/; PubMed
The journal: https://conductscience.org/library/journal-index/9436481; PubMed
Citations, by iCite: 516; iCite
Relative citation ratio, by iCite: 15.4; iCite
Revised in PubMed: 2022-04-08; PubMed

Authors9

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Liu X	Xiaoli
2	Bishop J	Justin
3	Shan Y	Yuan
4	Pai S	Sara
5	Liu D	Dingxie
6	Murugan AK	Avaniyapuram Kannan
7	Sun H	Hui
8	El-Naggar AK	Adel K
9	Xing M	Mingzhao

Source PubMed

Topics7

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Telomerase	Major topic
Thyroid Neoplasms	Major topic
Cell Line, Tumor
Humans
Mutation
Promoter Regions, Genetic
Proto-Oncogene Proteins B-raf

Source PubMed

Grants3

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
R01 CA113507	NCI NIH HHS	United States	R01CA113507	PubMed and NIH	NIH RePORTER
R01 CA134225	NCI NIH HHS	United States	R01CA134225	PubMed and NIH	NIH RePORTER
R01-CA134225	NCI NIH HHS	United States	R01CA134225	PubMed and NIH	NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections1

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

Kind	PMID	Title	In Papers
Comment in	23,817,291	Thyroid gland: Mutations identified in thyroid cancer.	https://conductscience.org/library/papers/23817291

Source PubMed

References23

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	23,348,503	TERT promoter mutations in familial and sporadic melanoma.	Science	2013	https://conductscience.org/library/papers/23348503	PubMed
2	23,157,292	Telomerase RNA biosynthesis and processing.	Biochemistry (Mosc)	2012	https://conductscience.org/library/papers/23157292	PubMed
3	23,130,564	American Thyroid Association guidelines for management of patients with anaplastic thyroid cancer.	Thyroid	2012	https://conductscience.org/library/papers/23130564	PubMed
4	21,296,855	Global cancer statistics.	CA Cancer J Clin	2011	https://conductscience.org/library/papers/21296855	PubMed
5	20,174,895	Papillary carcinoma tall cell variant (TCV): a review.	Endocr Pathol	2010	https://conductscience.org/library/papers/20174895	PubMed
6	12,068,308	Mutations of the BRAF gene in human cancer.	Nature	2002	https://conductscience.org/library/papers/12068308	PubMed
7	16,174,717	BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer.	J Clin Endocrinol Metab	2005	https://conductscience.org/library/papers/16174717	PubMed
8	15,947,100	BRAF mutation in thyroid cancer.	Endocr Relat Cancer	2005	https://conductscience.org/library/papers/15947100	PubMed
9	23,571,588	Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer.	JAMA	2013	https://conductscience.org/library/papers/23571588	PubMed
10	23,253,475	Telomerase and the search for the end of cancer.	Trends Mol Med	2013	https://conductscience.org/library/papers/23253475	PubMed

1 to 10 of 23

See all 23 references

Cited by331

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 516 citations.

PMID	Title	Journal	Year	In Papers	Source
42,959,152	Isolated TERT promoter mutation may define a high-risk prognostic subgroup in papillary thyroid carcinoma: an exploratory, hypothesis-generating analysis of TCGA and GSE33630 datasets.	Front Endocrinol (Lausanne)	2026	https://conductscience.org/library/papers/42959152	PubMed
42,876,643	Two-year dynamic risk stratification and adjuvant radioiodine efficacy in initial non-distant metastatic papillary thyroid carcinoma harboring TERT promoter mutations.	Front Oncol	2026	https://conductscience.org/library/papers/42876643	PubMed
42,866,471	Treatment strategies for unilateral papillary thyroid carcinoma with ipsilateral cervical lymph node metastasis: a narrative review.	Gland Surg	2026	https://conductscience.org/library/papers/42866471	PubMed
42,814,126	EIF1AX Mutations in thyroid nodules and advanced thyroid carcinoma: a systematic review and meta-analysis.	Virchows Arch	2026	https://conductscience.org/library/papers/42814126	PubMed
42,804,115	The impact of RET fusions on radioiodine avidity and prognosis in patients with distant metastatic papillary thyroid cancer.	Endocrine	2026	https://conductscience.org/library/papers/42804115	PubMed
42,653,308	Microenvironmental Control of Thyroid Cancer Plasticity and Radioiodine Resistance.	Int J Mol Sci	2026	https://conductscience.org/library/papers/42653308	PubMed
42,520,968	Follicular-Patterned Lesions of the Thyroid Gland.	Mod Pathol	2026	https://conductscience.org/library/papers/42520968	PubMed
42,475,304	Association between autoimmune thyroiditis and BRAFV600E/TERT promoter mutations in patients with papillary thyroid carcinoma from Central Asia, Kazakhstan.	PLoS One	2026	https://conductscience.org/library/papers/42475304	PubMed
42,353,188	Targeting the Warburg Effect in Anaplastic Thyroid Carcinoma: Metabolic Vulnerabilities and Therapeutic Opportunities.	Int J Mol Sci	2026	https://conductscience.org/library/papers/42353188	PubMed
42,339,087	LncRNA GAS8-AS1 is downregulated, correlates with early-stage disease and lymph node metastasis, and its knockdown promotes proliferation, migration, and invasion in differentiated thyroid cancer.	Front Endocrinol (Lausanne)	2026	https://conductscience.org/library/papers/42339087	PubMed

1 to 10 of 331

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Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
BRAF	673	PubTator's text mining	https://conductscience.org/library/genes/673	NCBI Gene
TERT	7,015	PubTator's text mining	https://conductscience.org/library/genes/7015	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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