Paper · 42963802

Evolution and function of genetic polymorphisms in the Helicobacter pylori type IV secretion pilus protein CagL in gastric carcinogenesis.

Tegtmeyer N and 8 others. Cell Commun Signal, 2026.

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ConductScience Library. Evolution and function of genetic polymorphisms in the Helicobacter pylori type IV secretion pilus protein CagL in gastric carcinogenesis. Papers, record 42963802. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42963802

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Paper

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Title: Evolution and function of genetic polymorphisms in the Helicobacter pylori type IV secretion pilus protein CagL in gastric carcinogenesis.
Journal: Cell Commun Signal
Year: 2026
Publication types: Journal Article
PubMed: https://pubmed.ncbi.nlm.nih.gov/42963802/
DOI: https://doi.org/10.1186/s12964-026-03334-9
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC13721428/
The journal: https://conductscience.org/library/journal-index/101170464
Revised in PubMed: 2026-11-01

Source PubMed

Authors9

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	ORCID iD
1	Tegtmeyer N	Nicole	https://orcid.org/0000-0002-6300-1831
2	Romero-Gallo J	Judith	https://orcid.org/0000-0002-6023-7793
3	Linz B	Bodo	https://orcid.org/0000-0003-4987-0587
4	Piazuelo MB	Maria Blanca	https://orcid.org/0000-0002-0000-1324
5	Noman O	Omar	https://orcid.org/0000-0003-0902-6381
6	Rohde M	Manfred
7	Sticht H	Heinrich	https://orcid.org/0000-0001-5644-045X
8	Peek RM Jr	Richard M	https://orcid.org/0000-0002-4836-5960
9	Backert S	Steffen	https://orcid.org/0000-0002-8948-8254

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Helicobacter pylori	Major topic
Bacterial Proteins	Major topic
Polymorphism, Genetic	Major topic
Stomach Neoplasms	Major topic
Type IV Secretion Systems	Major topic
Carcinogenesis	Major topic
Evolution, Molecular	Major topic
Animals
Humans
Gerbillinae
Helicobacter Infections

Source PubMed

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None in this release.

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Comments and corrections0

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References98

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	14,727,687	Persistent Helicobacter pylori infection and genetic polymorphisms of the host.	Nagoya J Med Sci	2003	https://conductscience.org/library/papers/14727687	PubMed
2	26,059,619	Composition, structure and function of the Helicobacter pylori cag pathogenicity island encoded type IV secretion system.	Future Microbiol	2015	https://conductscience.org/library/papers/26059619	PubMed
3	34,328,245	TIFA has dual functions in Helicobacter pylori-induced classical and alternative NF-κB pathways.	EMBO Rep	2021	https://conductscience.org/library/papers/34328245	PubMed
4	21,637,017	Life at the margins: modulation of attachment proteins in Helicobacter pylori.	Gut Microbes	2011	https://conductscience.org/library/papers/21637017	PubMed
5	21,374,738	H. pylori cagL amino acid sequence polymorphism Y58E59 induces a corpus shift of gastric integrin α5β1 related with gastric carcinogenesis.	Mol Carcinog	2011	https://conductscience.org/library/papers/21374738	PubMed
6	26,908,724	Helicobacter pylori CagL Hypervariable Motif: A Global Analysis of Geographical Diversity and Association With Gastric Cancer.	J Infect Dis	2016	https://conductscience.org/library/papers/26908724	PubMed
7	37,081,005	Helicobacter pylori infection.	Nat Rev Dis Primers	2023	https://conductscience.org/library/papers/37081005	PubMed
8	28,069,057	Bacterial serine protease HtrA as a promising new target for antimicrobial therapy?	Cell Commun Signal	2017	https://conductscience.org/library/papers/28069057	PubMed
9	16,885,455	Characterization of the pilin ortholog of the Helicobacter pylori type IV cag pathogenicity apparatus, a surface-associated protein expressed during infection.	J Bacteriol	2006	https://conductscience.org/library/papers/16885455	PubMed
10	29,722,887	MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms.	Mol Biol Evol	2018	https://conductscience.org/library/papers/29722887	PubMed

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Cited by0

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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NIH RePORTER's grant and paper linksPublic domain
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PMC's ID filePublic domain (US government)
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PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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