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Paper · 42972057

The genomic and epigenomic evolution of colorectal cancer.

Sng CCT and 3 others. Nat Rev Gastroenterol Hepatol, 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. The genomic and epigenomic evolution of colorectal cancer. Papers, record 42972057. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42972057

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The genomic and epigenomic evolution of colorectal cancer.
Journal
Nat Rev Gastroenterol Hepatol
Year
2026
Publication types
Journal Article, Review
Revised in PubMed
2026-11-02

Source PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Sng CCTChristopher C Thttps://orcid.org/0000-0003-2850-1467
2Starling NNaureen
3Graham TATrevor Ahttps://orcid.org/0000-0001-9582-1597
4Sottoriva AAndreahttps://orcid.org/0000-0001-6709-9533

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References254

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
12,188,735A genetic model for colorectal tumorigenesis.Cell1990https://conductscience.org/library/papers/2188735PubMed
26,499,378The evolution of colorectal carcinoma.Clin Radiol1984https://conductscience.org/library/papers/6499378PubMed
325,665,006A Big Bang model of human colorectal tumor growth.Nat Genet2015https://conductscience.org/library/papers/25665006PubMed
436,289,336Phenotypic plasticity and genetic control in colorectal cancer evolution.Nature2022https://conductscience.org/library/papers/36289336PubMed
536,289,335The co-evolution of the genome and epigenome in colorectal cancer.Nature2022https://conductscience.org/library/papers/36289335PubMed
623,704,319Hypomethylation of long interspersed nuclear element-1 (LINE-1) leads to activation of proto-oncogenes in human colorectal cancer metastasis.Gut2014https://conductscience.org/library/papers/23704319PubMed
738,071,119Plastic persisters: revival stem cells in colorectal cancer.Trends Cancer2024https://conductscience.org/library/papers/38071119PubMed
839,478,232Progressive plasticity during colorectal cancer metastasis.Nature2025https://conductscience.org/library/papers/39478232PubMed
941,193,656Epigenetically driven and early immune evasion in colorectal cancer evolution.Nat Genet2025https://conductscience.org/library/papers/41193656PubMed
1026,193,902Evolutionary determinants of cancer.Cancer Discov2015https://conductscience.org/library/papers/26193902PubMed

Cited by0

The papers in our copy of PubMed whose reference list names this one, newest first.

None in this release.

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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