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Paper · 39478232

Progressive plasticity during colorectal cancer metastasis.

Moorman A and 38 others. Nature, 2025. Cited by 159 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Progressive plasticity during colorectal cancer metastasis. Papers, record 39478232. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/39478232

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Progressive plasticity during colorectal cancer metastasis.
PubMed
Journal
Nature
PubMed
Year
2025
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural
PubMed
Citations, by iCite
159
iCite
Relative citation ratio, by iCite
34.81, provisional
iCite
Revised in PubMed
2026-11-02
PubMed

Authors39

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Moorman AAndrew
2Benitez EKElizabeth K
3Cambuli FFrancesco
4Jiang QQingwen
5Mahmoud AAhmed
6Lumish MMelissahttps://orcid.org/0000-0003-4173-5567
7Hartner SSaskiahttps://orcid.org/0009-0006-1030-1191
8Balkaran SSashahttps://orcid.org/0000-0001-9991-6649
9Bermeo JJonathanhttps://orcid.org/0000-0002-9553-9222
10Asawa SSimranhttps://orcid.org/0000-0001-9015-254X

1 to 10 of 39Source PubMed

See all 39 authors

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Colorectal NeoplasmsMajor topic
Neoplasm MetastasisMajor topic
Cell PlasticityMajor topic
Disease ProgressionMajor topic
Humans
Organoids
Cell Differentiation
Cell Lineage
Homeodomain Proteins
Tumor Suppressor Proteins
Female
Male
Neoplastic Stem Cells
Intestines
Tumor Microenvironment

Source PubMed

Grants9

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
U54 CA274492NCI NIH HHSUnited StatesU54CA274492PubMed and NIHNIH RePORTER
T32 GM152349NIGMS NIH HHSUnited StatesT32GM152349PubMedNIH RePORTER
P30 CA008748NCI NIH HHSUnited StatesP30CA008748PubMed and NIHNIH RePORTER
K08 CA230213NCI NIH HHSUnited StatesK08CA230213PubMed and NIHNIH RePORTER
U2C CA233284NCI NIH HHSUnited StatesU2CCA233284PubMed and NIHNIH RePORTER
U54 CA209975NCI NIH HHSUnited StatesU54CA209975PubMed and NIHNIH RePORTER
R37 CA266185NCI NIH HHSUnited StatesR37CA266185PubMed and NIHNIH RePORTER
R01EB027498NIHNIH RePORTER
T32GM007739NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections3

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

KindPMIDTitleIn PapersSource
Erratum in39,789,339Author Correction: Progressive plasticity during colorectal cancer metastasis.https://conductscience.org/library/papers/39789339PubMed
Erratum in42,557,335Publisher Correction: Progressive plasticity during colorectal cancer metastasis.https://conductscience.org/library/papers/42557335PubMed
Update of37,662,289PubMed

References77

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
137,059,065Metastasis.Cell2023https://conductscience.org/library/papers/37059065PubMed
235,022,204Hallmarks of Cancer: New Dimensions.Cancer Discov2022https://conductscience.org/library/papers/35022204PubMed
329,316,426Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer.Cancer Cell2018https://conductscience.org/library/papers/29316426PubMed
435,120,664Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients.Cell2022https://conductscience.org/library/papers/35120664PubMed
537,165,194Pan-cancer whole-genome comparison of primary and metastatic solid tumours.Nature2023https://conductscience.org/library/papers/37165194PubMed
619,092,804Crypt stem cells as the cells-of-origin of intestinal cancer.Nature2009https://conductscience.org/library/papers/19092804PubMed
724,282,287LGR5 positivity defines stem-like cells in colorectal cancer.Carcinogenesis2014https://conductscience.org/library/papers/24282287PubMed
832,169,167Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer.Cell Stem Cell2020https://conductscience.org/library/papers/32169167PubMed
936,352,230Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells.Nature2022https://conductscience.org/library/papers/36352230PubMed
1032,656,539L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer.Nat Cancer2020https://conductscience.org/library/papers/32656539PubMed

1 to 10 of 77

See all 77 references

Cited by134

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 159 citations.

PMIDTitleJournalYearIn PapersSource
42,985,075Reprogramming cancer at the tipping point.J Natl Cancer Cent2026https://conductscience.org/library/papers/42985075PubMed
42,982,889Longitudinal single-cell profiling of breast tumors highlights immune and epigenetic mechanisms associated with sensitivity to aromatase inhibitors.Nat Genet2026https://conductscience.org/library/papers/42982889PubMed
42,972,081A selective TNKS2 inhibitor for tumor-restricted WNT suppression.Nat Chem Biol2026https://conductscience.org/library/papers/42972081PubMed
42,972,057The genomic and epigenomic evolution of colorectal cancer.Nat Rev Gastroenterol Hepatol2026https://conductscience.org/library/papers/42972057PubMed
42,926,559Niche-dependent epistasis within the cancer genome shapes metastatic fitness.bioRxiv2026https://conductscience.org/library/papers/42926559PubMed
42,925,343Histopathological growth patterns represent a dynamic biological and clinically-relevant terminus of the metastatic cascade.Cancer Metastasis Rev2026https://conductscience.org/library/papers/42925343PubMed
42,902,326Cancer metastasis: biological mechanisms, therapeutic bottlenecks, and emerging interventions.J Hematol Oncol2026https://conductscience.org/library/papers/42902326PubMed
42,897,542Patient-derived organoids for precision oncology in colorectal cancer: from tumor modeling to clinical translation.Mol Cancer2026https://conductscience.org/library/papers/42897542PubMed
42,875,898Rational structure-guided identification of a Bcl-2-targeting peptide with antiproliferative effects on colorectal cancer cells.J Enzyme Inhib Med Chem2026https://conductscience.org/library/papers/42875898PubMed
42,875,653Reframing cancer therapy through tumor plasticity.Nat Cancer2026https://conductscience.org/library/papers/42875653PubMed

1 to 10 of 134

See all 134 cited by

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
LGR58,549PubTator's text mininghttps://conductscience.org/library/genes/8549NCBI Gene
PROX15,629PubTator's text mininghttps://conductscience.org/library/genes/5629NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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