Paper4297939

Potassium ions and the secretion of insulin by islets of Langerhans incubated in vitro.

Howell SL and 1 other. Biochem J, 1968. Cited by 367 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Potassium ions and the secretion of insulin by islets of Langerhans incubated in vitro. Papers, record 4297939. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4297939

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Potassium ions and the secretion of insulin by islets of Langerhans incubated in vitro.; PubMed
Journal: Biochem J; PubMed
Year: 1968; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/4297939/; PubMed
DOI: https://doi.org/10.1042/bj1080017; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC1198764/; PubMed
The journal: https://conductscience.org/library/journal-index/2984726R; PubMed
Citations, by iCite: 367; iCite
Revised in PubMed: 2019-05-01; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Howell SL	S L
2	Taylor KW	K W

Source PubMed

Topics21

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Insulin	Major topic
Islets of Langerhans	Major topic
Pancreas	Major topic
Potassium	Major topic
Animals
Depression, Chemical
Glucose
Immunoassay
In Vitro Techniques
Insulin Secretion
Iodine Isotopes
Leucine
Male
Methods
Microbial Collagenase
Ouabain
Potassium Isotopes
Rabbits
Stimulation, Chemical
Tolbutamide
Tritium

Source PubMed

Show 15 more topicsShow fewer topics

References29

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
2	6,031,791	Stimulation of insulin secretion by theophylline.	Nature	1967	https://conductscience.org/library/papers/6031791	PubMed
3	5,921,350	Effects of the cardiac glycosides on the Ca++ uptake of cardiac sarcoplasmic reticulum.	J Pharmacol Exp Ther	1966	https://conductscience.org/library/papers/5921350	PubMed
5	6,035,841	Influence of K-ions and adrenaline on the adenosine 3',-5'-monophosphate content in rat diaphragm.	Acta Physiol Scand	1967	https://conductscience.org/library/papers/6035841	PubMed
6	14,434,402	Membrane adenosine triphosphatase as a participant in the active transport of sodium and potassium in the human erythrocyte.	J Biol Chem	1960	https://conductscience.org/library/papers/14434402	PubMed
8	16,992,230	Release of vasopressin and oxytocin from isolated pituitary glands of adult and new-born rats.	J Physiol	1966	https://conductscience.org/library/papers/16992230	PubMed
9	16,742,511	The secretion of newly synthesized insulin in vitro.	Biochem J	1967	https://conductscience.org/library/papers/16742511	PubMed
10	5,320,084	Regulation of insulin secretion studied with pieces of rabbit pancreas incubated in vitro.	Biochem J	1964	https://conductscience.org/library/papers/5320084	PubMed
11	14,195,691	STIMULUS-SECRETION COUPLING IN A NEUROSECRETORY ORGAN: THE ROLE OF CALCIUM IN THE RELEASE OF VASOPRESSIN FROM THE NEUROHYPOPHYSIS.	J Physiol	1964	https://conductscience.org/library/papers/14195691	PubMed
12	6,037,369	The sodium pump and insulin secretion.	Biochim Biophys Acta	1967	https://conductscience.org/library/papers/6037369	PubMed
13	4,291,730	Effects of acetylcholine and other medullary secretagogues and antagonists on the membrane potential of adrenal chromaffin cells: an analysis employing techniques of tissue culture.	J Physiol	1967	https://conductscience.org/library/papers/4291730	PubMed
14	5,957,483	Cation requirements for insulin secretion in the isolated perfused pancreas.	Diabetes	1966	https://conductscience.org/library/papers/5957483	PubMed
15	5,339,718	Effects of glucose concentration on incorporation of [3H]leucine into insulin using isolated mammalian islets of Langerhans.	Biochim Biophys Acta	1966	https://conductscience.org/library/papers/5339718	PubMed
16	13,952,078	Immunoassay of insulin with insulin-antibody precipitate.	Biochem J	1963	https://conductscience.org/library/papers/13952078	PubMed
17	14,338,040	ISOLATION AND CULTURE OF THE ISLETS OF LANGERHANS OF THE GUINEA PIG.	Gen Comp Endocrinol	1965	https://conductscience.org/library/papers/14338040	PubMed
19	4,227,784	Control of glycolysis in cerebral cortex slices.	Biochem J	1967	https://conductscience.org/library/papers/4227784	PubMed
20	14,461,448	Electron microscopy of the beta cell of the pancreas.	Am J Med	1961	https://conductscience.org/library/papers/14461448	PubMed
21	4,903,553	The role of calcium and magnesium in insulin secretion from rabbit pancreas studied in vitro.	Diabetologia	1967	https://conductscience.org/library/papers/4903553	PubMed
22	5,841,677	Hypertension, the potassium ion and impaired carbohydrate tolerance.	N Engl J Med	1965	https://conductscience.org/library/papers/5841677	PubMed
23	14,300,765	THE FUNCTION OF 3'5' CYCLIC AMP IN ENZYME SECRETION.	Biochem Biophys Res Commun	1965	https://conductscience.org/library/papers/14300765	PubMed
24	5,339,448	Scanning methods: volume quantitation of tissues, cells and subcellular components.	J Histochem Cytochem	1966	https://conductscience.org/library/papers/5339448	PubMed

Show 14 more referencesShow fewer referencesSee all 29 references

Cited by113

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 367 citations.

PMID	Title	Journal	Year	In Papers	Source
42,179,566	Islet Proteome Remodeling and Proteostasis Disruption in HFSC-Fed Mice.	ACS Omega	2026	https://conductscience.org/library/papers/42179566	PubMed
41,957,738	Honey as a multifunctional natural product with health-promoting potential: comparative insights into antioxidant, antimicrobial, and DNA-protective activities.	BMC Complement Med Ther	2026	https://conductscience.org/library/papers/41957738	PubMed
39,488,731	Finerenone as a Novel Treatment for Gitelman Syndrome: A Case Study of a 35-Year-Old Male with Adrenal Mass and Hypokalemia.	Am J Case Rep	2024	https://conductscience.org/library/papers/39488731	PubMed
38,329,422	Navigating the multifaceted intricacies of the Na+-Cl- cotransporter, a highly regulated key effector in the control of hydromineral homeostasis.	Physiol Rev	2024	https://conductscience.org/library/papers/38329422	PubMed
38,318,620	Biosynthesis and characterization of silver nanoparticles synthesized using extracts of Agrimonia eupatoria L. and in vitro and in vivo studies of potential medicinal applications.	RSC Adv	2024	https://conductscience.org/library/papers/38318620	PubMed
31,728,004	Upregulation of caveolin-1 and its colocalization with cytokine receptors contributes to beta cell apoptosis.	Sci Rep	2019	https://conductscience.org/library/papers/31728004	PubMed
31,285,285	Resistance to Insulin in Patients with Gitelman Syndrome and a Subtle Intermediate Phenotype in Heterozygous Carriers: A Cross-Sectional Study.	J Am Soc Nephrol	2019	https://conductscience.org/library/papers/31285285	PubMed
28,432,081	Glucose tolerance and insulin responsiveness in Gitelman syndrome patients.	Endocr Connect	2017	https://conductscience.org/library/papers/28432081	PubMed
27,167,131	Environmental Presence of Hexavalent but Not Trivalent Chromium Causes Neurotoxicity in Exposed Drosophila melanogaster.	Mol Neurobiol	2017	https://conductscience.org/library/papers/27167131	PubMed
26,634,368	The role of dietary potassium in hypertension and diabetes.	J Physiol Biochem	2016	https://conductscience.org/library/papers/26634368	PubMed
26,070,436	Betacellulin ameliorates hyperglycemia in obese diabetic db/db mice.	J Mol Med (Berl)	2015	https://conductscience.org/library/papers/26070436	PubMed
19,903,331	Glutamate (mGluR-5) gene expression in brain regions of streptozotocin induced diabetic rats as a function of age: role in regulation of calcium release from the pancreatic islets in vitro.	J Biomed Sci	2009	https://conductscience.org/library/papers/19903331	PubMed
19,866,773	ENZYME ACTIVITIES IN CHICK EMBRYONIC CARTILAGE : Their Subcellular Distribution in Isolated Chondrocytes.	J Cell Biol	1971	https://conductscience.org/library/papers/19866773	PubMed
18,981,326	Changes in serum potassium mediate thiazide-induced diabetes.	Hypertension	2008	https://conductscience.org/library/papers/18981326	PubMed
16,742,817	Effect of phenylpyruvate on enzymes involved in fatty acid synthesis in rat brain.	Biochem J	1973	https://conductscience.org/library/papers/16742817	PubMed
16,742,808	Regulation of insulin release from isolated islets of Langerhans of the rat in pregnancy. The role of adenosine 3':5'-cyclic monophosphate.	Biochem J	1973	https://conductscience.org/library/papers/16742808	PubMed
16,733,808	Increased insulin secretion by muscarinic M1 and M3 receptor function from rat pancreatic islets in vitro.	Neurochem Res	2006	https://conductscience.org/library/papers/16733808	PubMed
16,583,134	Enhanced beta-adrenergic receptors in the brain and pancreas during pancreatic regeneration in weanling rats.	Mol Cell Biochem	2006	https://conductscience.org/library/papers/16583134	PubMed
8,590,783	The effects of islet cell surface antibodies on the metabolic function of mouse islet B cells in vitro.	Acta Diabetol	1995	https://conductscience.org/library/papers/8590783	PubMed
8,436,251	Human autoantibodies react with glutamic acid decarboxylase antigen in human and rat but not in mouse pancreatic islets.	Diabetologia	1993	https://conductscience.org/library/papers/8436251	PubMed

Show 14 more cited byShow fewer cited bySee all 113 cited by

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes
INS	3,630	PubTator's text mining	https://conductscience.org/library/genes/3630

Source NCBI Gene

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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NIH RePORTER's grant and paper linksPublic domain
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PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
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