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Paper · 42980888

Advancing CLDN18.2-Targeted Therapies in Pancreatic Cancer: Current Clinical Development and Therapeutic Opportunities.

Yan H and 1 other. Curr Treat Options Oncol, 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Advancing CLDN18.2-Targeted Therapies in Pancreatic Cancer: Current Clinical Development and Therapeutic Opportunities. Papers, record 42980888. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42980888

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Advancing CLDN18.2-Targeted Therapies in Pancreatic Cancer: Current Clinical Development and Therapeutic Opportunities.
Journal
Curr Treat Options Oncol
Year
2026
Publication types
Journal Article, Review
Revised in PubMed
2026-11-06

Source PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Yan HHuanxin
2Shi XXiaolihttps://orcid.org/0009-0009-8007-0327

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Pancreatic NeoplasmsMajor topic
ClaudinsMajor topic
Molecular Targeted TherapyMajor topic
Humans
Biomarkers, Tumor
Antibodies, Bispecific
Treatment Outcome
Immunoconjugates
Clinical Trials as Topic

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References51

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
141,930,337Antibody-Drug Conjugates in Oncology: Principles, Clinical Development, and Future Directions.MedComm (2020)2026https://conductscience.org/library/papers/41930337PubMed
241,969,434
The claudin-18.2-CD3 bispecific antibody IBI389 exerts an antitumor effect on malignant tumors with positive claudin-18.2 expression by promoting T-cell infiltration and remodeling the tumor immune microenvironment.
Transl Cancer Res2026https://conductscience.org/library/papers/41969434PubMed
339,835,140Advances in CAR T cell therapy: antigen selection, modifications, and current trials for solid tumors.Front Immunol2024https://conductscience.org/library/papers/39835140PubMed
440,615,715Challenges and perspectives of CAR-T cell therapy in solid tumours: insights from gastric cancer.Br J Cancer2025https://conductscience.org/library/papers/40615715PubMed
539,637,967Emerging targets in gastric and pancreatic cancer: Focus on claudin 18.2.Cancer Lett2025https://conductscience.org/library/papers/39637967PubMed
641,019,366Targeting Claudin18.2 for cancer theranostics: From molecular imaging to precision therapy.iScience2025https://conductscience.org/library/papers/41019366PubMed
740,233,718CAR-T therapy in solid tumors.Cancer Cell2025https://conductscience.org/library/papers/40233718PubMed
837,719,370Bispecific antibodies in cancer therapy: Target selection and regulatory requirements.Acta Pharm Sin B2023https://conductscience.org/library/papers/37719370PubMed
938,448,606The present and future of bispecific antibodies for cancer therapy.Nat Rev Drug Discov2024https://conductscience.org/library/papers/38448606PubMed
1042,294,061Signaling pathway mechanisms in pancreatic ductal adenocarcinoma tumor microenvironment and emerging targeting strategies for improved prognosis.Oncol Rev2026https://conductscience.org/library/papers/42294061PubMed

Cited by0

The papers in our copy of PubMed whose reference list names this one, newest first.

None in this release.

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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