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Paper · 4348209

Insulin-receptor interaction in the obese-hyperglycemic mouse. A model of insulin resistance.

Kahn CR and 2 others. J Biol Chem, 1973. Cited by 468 papers, by iCite.

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ConductScience Library. Insulin-receptor interaction in the obese-hyperglycemic mouse. A model of insulin resistance. Papers, record 4348209. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4348209

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Insulin-receptor interaction in the obese-hyperglycemic mouse. A model of insulin resistance.
PubMed
Journal
J Biol Chem
PubMed
Year
1973
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
468
iCite
Relative citation ratio, by iCite
10.6
iCite
Revised in PubMed
2021-03-13
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Kahn CRC R
2Neville DM JrD M
3Roth JJ

Source PubMed

Topics21

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
HypoglycemiaMajor topic
InsulinMajor topic
Insulin ResistanceMajor topic
LiverMajor topic
ObesityMajor topic
Receptors, Cell SurfaceMajor topic
Animals
Cell Fractionation
Cell Membrane
Electrophoresis, Disc
Genetics
Glucagon
Growth Hormone
Insulin Antibodies
Iodine Isotopes
Isoproterenol
Mice
Mice, Inbred C57BL
Microscopy, Phase-Contrast
Protein Binding
Proteins

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by95

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 468 citations.

PMIDTitleJournalYearIn PapersSource
41,463,398Insulin Resistance at the Crossroads of Metabolic Inflammation, Cardiovascular Disease, Organ Failure and Cancer.Biomolecules2025https://conductscience.org/library/papers/41463398PubMed
40,105,689IGF1 Signaling Regulates Neuropeptide Expression in Hypothalamic Neurons Under Physiological and Pathological Conditions.Endocrinology2025https://conductscience.org/library/papers/40105689PubMed
39,966,374Energy metabolism in health and diseases.Signal Transduct Target Ther2025https://conductscience.org/library/papers/39966374PubMed
39,948,335Pancreatic endocrine and exocrine signaling and crosstalk in physiological and pathological status.Signal Transduct Target Ther2025https://conductscience.org/library/papers/39948335PubMed
39,107,318Cell-cell communication: new insights and clinical implications.Signal Transduct Target Ther2024https://conductscience.org/library/papers/39107318PubMed
36,238,467PRL/PRLR Can Promote Insulin Resistance by Activating the JAK2/STAT5 Signaling Pathway.Comput Math Methods Med2022https://conductscience.org/library/papers/36238467PubMed
34,717,954The insulin centennial-100 years of milestones in biochemistry.J Biol Chem2021https://conductscience.org/library/papers/34717954PubMed
34,717,951The insulin centennial-100 years of milestones in biochemistry.J Lipid Res2021https://conductscience.org/library/papers/34717951PubMed
34,512,548The Association of Trp64Arg Polymorphism in the Beta-Adrenergic Receptor With Insulin Resistance: Meta-Analysis.Front Endocrinol (Lausanne)2021https://conductscience.org/library/papers/34512548PubMed
32,183,843Glucose, insulin, insulin receptor subunits α and β in normal and spontaneously diabetic and obese ob/ob and db/db infertile mouse testis and hypophysis.Reprod Biol Endocrinol2020https://conductscience.org/library/papers/32183843PubMed

1 to 10 of 95

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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