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Paper438333

Effects of metoclopramide and bromocriptine on the renin-angiotensin-aldosterone system in man. Dopaminergic control of aldosterone.

Carey RM and 2 others. J Clin Invest, 1979. Cited by 267 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Effects of metoclopramide and bromocriptine on the renin-angiotensin-aldosterone system in man. Dopaminergic control of aldosterone. Papers, record 438333. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/438333

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Effects of metoclopramide and bromocriptine on the renin-angiotensin-aldosterone system in man. Dopaminergic control of aldosterone.
PubMed
Journal
J Clin Invest
PubMed
Year
1979
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
267
iCite
Relative citation ratio, by iCite
11.5
iCite
Revised in PubMed
2018-11-13
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Carey RMR M
2Thorner MOM O
3Ortt EME M

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
AldosteroneMajor topic
Angiotensin IIMajor topic
BromocriptineMajor topic
DopamineMajor topic
MetoclopramideMajor topic
ReninMajor topic
11-Hydroxycorticosteroids
Adult
Blood Pressure
Humans
Kinetics
Male
Potassium
Prolactin
Sodium

Source PubMed

References28

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
114,471,419A simple fluorimetric method for the estimation of free 11-hydroxycorticoids in human plasma.J Clin Pathol1962https://conductscience.org/library/papers/14471419PubMed
2206,089Experimental and clinical studies on bromocriptine in the Parkinsonian syndrome.Acta Endocrinol Suppl (Copenh)1978https://conductscience.org/library/papers/206089PubMed
3194,447Lack of effect of prolactin inhibition by alpha-bromoergocriptine (CB 154) on plasma aldosterone in anephric and non-nephrectomized patients on regular haemodialysis.Acta Endocrinol (Copenh)1977https://conductscience.org/library/papers/194447PubMed
425,553Cardiovascular actions of bromocriptine.Acta Endocrinol Suppl (Copenh)1978https://conductscience.org/library/papers/25553PubMed
511,140Dopamine as a possible neurotransmitter in gastric relaxation.Gastroenterology1976https://conductscience.org/library/papers/11140PubMed
6188,283Gustatory-alimentary reflex inhibition of aldosterone hypersecretion by the autotransplanted adrenal gland of sodium deficient sheep.Acta Endocrinol (Copenh)1977https://conductscience.org/library/papers/188283PubMed
7401,826Studies on the nature of thyroidal suppression during acute falciparum malaria: integrity of pituitary response to TRH and alterations in serum T3 and reverse T3.J Clin Endocrinol Metab1977https://conductscience.org/library/papers/401826PubMed
8591,626Metoclopramide increases plasma aldosterone concentration in man.J Clin Endocrinol Metab1977https://conductscience.org/library/papers/591626PubMed
9925,132
Evidence against prolactin stimulation of aldosterone in normal human subjects and patients with primary aldosteronism, including a patient with primary aldosteronism and a prolactin-producing pituitary microadenoma.
J Clin Endocrinol Metab1977https://conductscience.org/library/papers/925132PubMed
10839,976Effect of metoclopramide-induced prolactin on aldosterone secretion in normal subjects.Life Sci1977https://conductscience.org/library/papers/839976PubMed
111,009,679Effect of metroclopramide on serum prolactin levels in humans.Clin Endocrinol (Oxf)1976https://conductscience.org/library/papers/1009679PubMed
124,146,398Effect of ergot drugs on central catecholamine neurons: evidence for a stimulation of central dopamine neurons.J Pharm Pharmacol1973https://conductscience.org/library/papers/4146398PubMed
134,312,098Studies on the loci of action of stimuli to the biogenesis of aldosterone.Proc R Soc Med1969https://conductscience.org/library/papers/4312098PubMed
1453,377Inhibition of the plasma-aldosterone response to frusemide by bromocriptine.Lancet1975https://conductscience.org/library/papers/53377PubMed
154,631,065A homologous radioimmunoassay for human prolactin.J Clin Endocrinol Metab1973https://conductscience.org/library/papers/4631065PubMed
1647,084Dopamine is an important neurotransmitter in the autonomic nervous system.Lancet1975https://conductscience.org/library/papers/47084PubMed
174,600,048Effects of dietary sodium and of acute saline infusion on the interrelationship between dopamine excretion and adrenergic activity in man.J Clin Invest1974https://conductscience.org/library/papers/4600048PubMed
18237,096Effect of metoclopramide on turnover of brain dopamine noradrenaline and 5-hydroxytryptamine.J Pharm Pharmacol1975https://conductscience.org/library/papers/237096PubMed
19239,122Cardiovascular dopamine receptor stimulation antagonized by metoclopramide.J Pharm Pharmacol1975https://conductscience.org/library/papers/239122PubMed
204,852,857Letter: Metaclopramide and prolactin.Br Med J1974https://conductscience.org/library/papers/4852857PubMed

See all 28 references

Cited by28

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 267 citations.

PMIDTitleJournalYearIn PapersSource
29,123,220Significance of dopamine D1 receptor signalling for steroidogenic differentiation of human induced pluripotent stem cells.Sci Rep2017https://conductscience.org/library/papers/29123220PubMed
21,690,484Exercise training versus propranolol in the treatment of the postural orthostatic tachycardia syndrome.Hypertension2011https://conductscience.org/library/papers/21690484PubMed
14,551,679Hyperreninemic hypoaldosteronism: a possible etiological factor of septic shock-induced acute renal failure.Intensive Care Med2003https://conductscience.org/library/papers/14551679PubMed
7,400,305Dopaminergic inhibition of metoclopramide-induced aldosterone secretion in man. Dissociation of responses to dopamine and bromocriptine.J Clin Invest1980https://conductscience.org/library/papers/7400305PubMed
6,871,536An investigation of the importance of the adrenal gland to the action of dopamine in the rat kidney.Br J Pharmacol1983https://conductscience.org/library/papers/6871536PubMed
6,752,560Rapid increase of mineralocorticoids after furosemide in low-renin essential hypertension: evidence for 18-hydroxycorticosterone to be a better marker than aldosterone.Klin Wochenschr1982https://conductscience.org/library/papers/6752560PubMed
6,713,512Primary tissue culture of human adrenocortical Conn's adenomata. Bromocriptine as a possible agonist-antagonist of angiotensin at the cellular level.Cell Tissue Res1984https://conductscience.org/library/papers/6713512PubMed
6,455,501The endocrine profile of bromocriptine: its application in endocrine diseases.J Neural Transm1981https://conductscience.org/library/papers/6455501PubMed
6,345,129Metoclopramide. An updated review of its pharmacological properties and clinical use.Drugs1983https://conductscience.org/library/papers/6345129PubMed
6,301,162The neuroendocrine response to multiple trauma.World J Surg1983https://conductscience.org/library/papers/6301162PubMed
6,286,976Dopaminergic inhibition of vasopressin-stimulated water flow in the toad bladder: evidence for local formation of dopamine.J Membr Biol1982https://conductscience.org/library/papers/6286976PubMed
6,150,942Selective peripheral dopamine-1 receptor stimulation with fenoldopam in human essential hypertension.J Clin Invest1984https://conductscience.org/library/papers/6150942PubMed
6,097,456Interference by ranitidine with aldosterone secretion in vivo.Eur J Clin Pharmacol1984https://conductscience.org/library/papers/6097456PubMed
6,096,435Role of dopamine in the regulation of aldosterone and 18-hydroxycorticosterone secretion in man.J Endocrinol Invest1984https://conductscience.org/library/papers/6096435PubMed
4,054,204Effects of the dopaminergic agonist cianergoline on blood pressure, the renin-angiotensin-aldosterone axis and the sympathetic nervous system in patients with essential hypertension.Eur J Clin Pharmacol1985https://conductscience.org/library/papers/4054204PubMed
3,938,783Histochemical localization of monoamine oxidase types A and B in the adrenal gland.Histochem J1985https://conductscience.org/library/papers/3938783PubMed
3,886,384The effect of dopamine administration on the activity of the renin-angiotensin-aldosterone system in sick preterm infants.Eur J Pediatr1985https://conductscience.org/library/papers/3886384PubMed
3,366,164Aldosterone response to metoclopramide is mediated through the autonomic nervous system in man.Eur J Clin Pharmacol1988https://conductscience.org/library/papers/3366164PubMed
3,087,398Domperidone treatment in man inhibits the fall in plasma renin activity induced by intravenous gamma-L-glutamyl-L-dopa.Br J Clin Pharmacol1986https://conductscience.org/library/papers/3087398PubMed
3,039,452Effects of prolactin on Na-K-ATPase activity along the rat nephron.Pflugers Arch1987https://conductscience.org/library/papers/3039452PubMed

See all 28 cited by

Genes3

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
AGT183PubTator's text mininghttps://conductscience.org/library/genes/183NCBI Gene
PRL5,617PubTator's text mininghttps://conductscience.org/library/genes/5617NCBI Gene
REN5,972PubTator's text mininghttps://conductscience.org/library/genes/5972NCBI Gene

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

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  • Data

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  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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