Paper · 4516600

Purification and sequence of messenger RNA for immunoglobulin light chains.

Brownlee GG and 4 others. Nat New Biol, 1973. Cited by 93 papers, by iCite.

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ConductScience Library. Purification and sequence of messenger RNA for immunoglobulin light chains. Papers, record 4516600. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4516600

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Purification and sequence of messenger RNA for immunoglobulin light chains.; PubMed
Journal: Nat New Biol; PubMed
Year: 1973; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/4516600/; PubMed
DOI: https://doi.org/10.1038/newbio244236a0; PubMed
The journal: https://conductscience.org/library/journal-index/0410463; PubMed
Citations, by iCite: 93; iCite
Relative citation ratio, by iCite: 2.13; iCite
Revised in PubMed: 2019-09-08; PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Brownlee GG	G G
2	Cartwright EM	E M
3	Cowan NJ	N J
4	Jarvis JM	J M
5	Milstein C	C

Source PubMed

Topics20

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Immunoglobulin Fragments	Major topic
Nucleotides	Major topic
RNA, Messenger	Major topic
Animals
Base Sequence
Cell Line
Centrifugation, Density Gradient
Chromatography, DEAE-Cellulose
Electrophoresis, Polyacrylamide Gel
Genetic Code
Hydrolysis
Iontophoresis
Mice
Microsomes
Molecular Weight
Multiple Myeloma
Phosphorus Isotopes
RNA
RNA, Neoplasm
Ribonucleases

Source PubMed

Grants0

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None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

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Comments and corrections0

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References0

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Cited by21

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 93 citations.

PMID	Title	Journal	Year	In Papers	Source
21,896,654	Ending the message: poly(A) signals then and now.	Genes Dev	2011	https://conductscience.org/library/papers/21896654	PubMed
6,895,226	Involucrin synthesis is correlated with cell size in human epidermal cultures.	J Cell Biol	1981	https://conductscience.org/library/papers/6895226	PubMed
6,139,278	Interstrain conservation of the murine GAT-specific antibody V kappa repertoire as analyzed at the germline gene level.	EMBO J	1983	https://conductscience.org/library/papers/6139278	PubMed
4,583,027	In vivo splicing of protein: one continuous polypeptide from two independently functioning operons.	Proc Natl Acad Sci U S A	1973	https://conductscience.org/library/papers/4583027	PubMed
4,526,222	Estimation of the number of genes coding for the constant part of the mouse immunoglobulin kappa light chain.	Proc Natl Acad Sci U S A	1974	https://conductscience.org/library/papers/4526222	PubMed
4,366,765	The homopolyadenylate and adjacent nucleotides at the 3'-terminus of 30-40s RNA subunits in the genome of murine sarcoma-leukemia virus.	Proc Natl Acad Sci U S A	1974	https://conductscience.org/library/papers/4366765	PubMed
4,215,083	Organization of immunoglobulin genes: reiteration frequency of the mouse kappa chain constant region gene.	Proc Natl Acad Sci U S A	1974	https://conductscience.org/library/papers/4215083	PubMed
4,215,074	Evidence for somatic generation of antibody diversity.	Proc Natl Acad Sci U S A	1974	https://conductscience.org/library/papers/4215074	PubMed
4,210,109	Evidence of homology between the beta-chain of human haptoglobin and the chymotrypsin family of serine proteases.	Biochem Genet	1974	https://conductscience.org/library/papers/4210109	PubMed
4,139,714	Nucleotide sequence analysis of RNA synthesized from rabbit globin complementary DNA.	Proc Natl Acad Sci U S A	1974	https://conductscience.org/library/papers/4139714	PubMed

1 to 10 of 21

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Genes0

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None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

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None in this release.

Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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