Paper466404

Capsaicin-evoked release of substance P from primary sensory neurons.

Theriault E and 2 others. Brain Res, 1979. Cited by 224 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Capsaicin-evoked release of substance P from primary sensory neurons. Papers, record 466404. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/466404

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Capsaicin-evoked release of substance P from primary sensory neurons.; PubMed
Journal: Brain Res; PubMed
Year: 1979; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/466404/; PubMed
DOI: https://doi.org/10.1016/0006-8993(79)90957-0; PubMed
The journal: https://conductscience.org/library/journal-index/0045503; PubMed
Citations, by iCite: 224; iCite
Relative citation ratio, by iCite: 9.41; iCite
Revised in PubMed: 2019-06-13; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Theriault E	E
2	Otsuka M	M
3	Jessell T	T

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Capsaicin	Major topic
Fatty Acids, Unsaturated	Major topic
Nociceptors	Major topic
Spinal Cord	Major topic
Substance P	Major topic
Animals
Calcium
Evoked Potentials
Motor Neurons
Radioimmunoassay
Rats

Source PubMed

Show 5 more topicsShow fewer topics

Cited by36

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 224 citations.

PMID	Title	Journal	Year	In Papers	Source
34,969,864	Profile of David Julius and Ardem Patapoutian: 2021 Nobel Laureates in Physiology or Medicine.	Proc Natl Acad Sci U S A	2022	https://conductscience.org/library/papers/34969864	PubMed
32,634,530	Substance P-expressing Neurons in the Superficial Dorsal Horn of the Mouse Spinal Cord: Insights into Their Functions and their Roles in Synaptic Circuits.	Neuroscience	2020	https://conductscience.org/library/papers/32634530	PubMed
23,894,327	Proteolysis controls endogenous substance P levels.	PLoS One	2013	https://conductscience.org/library/papers/23894327	PubMed
21,678,472	Sensory nerve induced inflammation contributes to heterotopic ossification.	J Cell Biochem	2011	https://conductscience.org/library/papers/21678472	PubMed
15,987,503	Substance P-driven feed-forward inhibitory activity in the mammalian spinal cord.	Mol Pain	2005	https://conductscience.org/library/papers/15987503	PubMed
8,938,667	Influence of several peptidase inhibitors on the pro-inflammatory effects of substance P, capsaicin and collagenase.	Naunyn Schmiedebergs Arch Pharmacol	1996	https://conductscience.org/library/papers/8938667	PubMed
8,891,761	The effect of cetirizine and loratadine on codeine-induced histamine release in human skin in vivo assessed by cutaneous microdialysis.	Inflamm Res	1996	https://conductscience.org/library/papers/8891761	PubMed
7,799,224	Selective phototoxic destruction of rat Merkel cells abolishes responses of slowly adapting type I mechanoreceptor units.	J Physiol	1994	https://conductscience.org/library/papers/7799224	PubMed
7,693,289	Muscarinic excitatory and inhibitory mechanisms involved in afferent fibre-evoked depolarization of motoneurones in the neonatal rat spinal cord.	Br J Pharmacol	1993	https://conductscience.org/library/papers/7693289	PubMed
6,472,498	Antinociceptive effects of neonatal capsaicin in rats with adjuvant arthritis.	Naunyn Schmiedebergs Arch Pharmacol	1984	https://conductscience.org/library/papers/6472498	PubMed
6,205,140	Supersensitivity of the rabbit iris sphincter muscle induced by trigeminal denervation: the role of substance P.	J Physiol	1984	https://conductscience.org/library/papers/6205140	PubMed
6,193,270	Capsaicin causes release of a substance P-like peptide in guinea-pig inferior mesenteric ganglia.	J Physiol	1983	https://conductscience.org/library/papers/6193270	PubMed
6,192,926	Widespread distribution of substance P- and somatostatin-immunoreactive elements in the spinal cord of the neonatal rat.	Cell Tissue Res	1983	https://conductscience.org/library/papers/6192926	PubMed
6,192,237	Structure-activity relationships for some substance P-related peptides that cause wheal and flare reactions in human skin.	J Physiol	1983	https://conductscience.org/library/papers/6192237	PubMed
6,190,773	International Substance P Symposium. Dublin, April 27-29, 1983. Abstracts.	Ir J Med Sci	1983	https://conductscience.org/library/papers/6190773	PubMed
6,185,670	Evidence that the contractile response of the guinea-pig ileum to capsaicin is due to release of substance P.	J Physiol	1982	https://conductscience.org/library/papers/6185670	PubMed
6,180,331	Evidence that the contractile response of the guinea-pig ileum to capsaicin is due to substance P release.	Naunyn Schmiedebergs Arch Pharmacol	1982	https://conductscience.org/library/papers/6180331	PubMed
6,180,329	Lack of effect of baclofen on substance P and somatostatin release from the spinal cord in vitro.	Naunyn Schmiedebergs Arch Pharmacol	1982	https://conductscience.org/library/papers/6180329	PubMed
6,173,367	Substance P-like immunoreactivity in the intramural nerve plexuses of the guinea-pig ureter: a light and electron microscopical study.	J Anat	1981	https://conductscience.org/library/papers/6173367	PubMed
6,170,988	Biological importance of the retrograde axonal transport of nerve growth factor in sensory neurons.	Proc Natl Acad Sci U S A	1981	https://conductscience.org/library/papers/6170988	PubMed

Show 14 more cited byShow fewer cited bySee all 36 cited by

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes
TAC1	6,863	PubTator's text mining	https://conductscience.org/library/genes/6863

Source NCBI Gene

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

None in this release

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Trials
Comments and corrections
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Data

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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