Paper · 46925

Studies on reverse transcriptase of RNA tumor viruses III. Properties of purified Moloney murine leukemia virus DNA polymerase and associated RNase H.

Verma IM. J Virol, 1975. Cited by 133 papers, by iCite.

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ConductScience Library. Studies on reverse transcriptase of RNA tumor viruses III. Properties of purified Moloney murine leukemia virus DNA polymerase and associated RNase H. Papers, record 46925. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/46925

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Studies on reverse transcriptase of RNA tumor viruses III. Properties of purified Moloney murine leukemia virus DNA polymerase and associated RNase H.; PubMed
Journal: J Virol; PubMed
Year: 1975; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/46925/; PubMed
DOI: https://doi.org/10.1128/jvi.15.4.843-854.1975; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC354528/; PubMed
The journal: https://conductscience.org/library/journal-index/0113724; PubMed
Citations, by iCite: 133; iCite
Relative citation ratio, by iCite: 2.86; iCite
Revised in PubMed: 2020-07-24; PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Verma IM	I M

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Moloney murine leukemia virus	Major topic
RNA-Directed DNA Polymerase	Major topic
Ribonucleases	Major topic
Centrifugation, Zonal
Electrophoresis, Polyacrylamide Gel
Magnesium
Manganese
Molecular Weight
Nucleic Acid Hybridization
Peptides
Phosphoric Diester Hydrolases
Polynucleotides
Templates, Genetic
Thymine Nucleotides
Transcription, Genetic
Tritium

Source PubMed

Grants0

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None in this release.

Trials0

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None in this release.

Comments and corrections0

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None in this release.

References40

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	4,359,488	Size and base composition of RNA in supercoiled plasmid DNA.	Proc Natl Acad Sci U S A	1973	https://conductscience.org/library/papers/4359488	PubMed
2	4,361,674	Integration of deoxyribonucleic acid specific for Rous sarcoma virus after infection of permissive and nonpermissive hosts.	Proc Natl Acad Sci U S A	1973	https://conductscience.org/library/papers/4361674	PubMed
3	46,281	Studies on reverse transcriptase of RNA tumor viruses. I. Localization of thermolabile DNA polymerase and RNase H activities on one polypeptide.	J Virol	1975	https://conductscience.org/library/papers/46281	PubMed
4	4,117,352	Reversible inactivation of the deoxyribonucleic acid polymerase of Rauscher leukemia virus.	J Virol	1972	https://conductscience.org/library/papers/4117352	PubMed
5	4,118,867	Ribonuclease H: a ubiquitous activity in virions of ribonucleic acid tumor viruses.	J Virol	1972	https://conductscience.org/library/papers/4118867	PubMed
6	4,119,223	A single subunit from avian myeloblastosis virus with both RNA-directed DNA polymerase and ribonuclease H activity.	Proc Natl Acad Sci U S A	1973	https://conductscience.org/library/papers/4119223	PubMed
7	4,119,789	Mechanism of action of ribonuclease H isolated from avian myeloblastosis virus and Escherichia coli.	Proc Natl Acad Sci U S A	1973	https://conductscience.org/library/papers/4119789	PubMed
8	4,132,918	Hamster leukemia virus: lack of endogenous DNA synthesis and unique structure of its DNA polymerase.	J Virol	1974	https://conductscience.org/library/papers/4132918	PubMed
9	4,134,616	Separation of ribonuclease H and RNA directed DNA polymerase (reverse transcriptase) of murine type-C RNA tumor viruses.	Proc Natl Acad Sci U S A	1974	https://conductscience.org/library/papers/4134616	PubMed
10	4,136,633	Different mode of action of ribonuclease H in purified alpha and alpha beta ribonucleic acid-directed deoxyribonucleic acid polymerase from avian myeloblastosis virus.	J Biol Chem	1974	https://conductscience.org/library/papers/4136633	PubMed

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Cited by57

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 133 citations.

PMID	Title	Journal	Year	In Papers	Source
42,847,241	DNA polymerase I and DnaE mediate RNA-templated DNA synthesis over embedded ribonucleotides.	Nucleic Acids Res	2026	https://conductscience.org/library/papers/42847241	PubMed
41,509,208	DNA polymerase I is an efficient reverse transcriptase that mediates RNA-templated DNA repair synthesis.	bioRxiv	2025	https://conductscience.org/library/papers/41509208	PubMed
41,327,310	Functions and applications of enzymes in nucleic acid nanotechnology.	J Nanobiotechnology	2025	https://conductscience.org/library/papers/41327310	PubMed
33,778,250	Quick and Easy Assembly of a One-Step qRT-PCR Kit for COVID-19 Diagnostics Using In-House Enzymes.	ACS Omega	2021	https://conductscience.org/library/papers/33778250	PubMed
28,160,599	Arm-specific cleavage and mutation during reverse transcription of 2΄,5΄-branched RNA by Moloney murine leukemia virus reverse transcriptase.	Nucleic Acids Res	2017	https://conductscience.org/library/papers/28160599	PubMed
11,413,304	Many nonmammalian cells exhibit postentry blocks to transduction by gammaretroviruses pseudotyped with various viral envelopes, including vesicular stomatitis virus G glycoprotein.	J Virol	2001	https://conductscience.org/library/papers/11413304	PubMed
11,233,988	Mapping of RNA accessible sites by extension of random oligonucleotide libraries with reverse transcriptase.	RNA	2001	https://conductscience.org/library/papers/11233988	PubMed
9,658,093	Human T-cell leukemia virus type 1 reverse transcriptase (RT) originates from the pro and pol open reading frames and requires the presence of RT-RNase H (RH) and RT-RH-integrase proteins for its activity.	J Virol	1998	https://conductscience.org/library/papers/9658093	PubMed
8,649,991	Relationship between plus strand DNA synthesis removal of downstream segments of RNA by human immunodeficiency virus, murine leukemia virus and avian myeloblastoma virus reverse transcriptases.	Nucleic Acids Res	1996	https://conductscience.org/library/papers/8649991	PubMed
7,506,526	Sulphydryl groups in the template-primer-binding domain of murine leukaemia virus reverse transcriptase. Identification and functional analysis of cysteine-90.	Biochem J	1993	https://conductscience.org/library/papers/7506526	PubMed

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Data0

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Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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