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Paper · 47900

Cell-mediated lympholysis of trinitrophenyl-modified autologous lymphocytes. Effector cell specificity to modified cell surface components controlled by H-2K and H-2D serological regions of the murine major histocompatibility complex.

Shearer GM and 2 others. J Exp Med, 1975. Cited by 471 papers, by iCite.

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ConductScience Library. Cell-mediated lympholysis of trinitrophenyl-modified autologous lymphocytes. Effector cell specificity to modified cell surface components controlled by H-2K and H-2D serological regions of the murine major histocompatibility complex. Papers, record 47900. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/47900

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Cell-mediated lympholysis of trinitrophenyl-modified autologous lymphocytes. Effector cell specificity to modified cell surface components controlled by H-2K and H-2D serological regions of the murine major histocompatibility complex.
PubMed
Journal
J Exp Med
PubMed
Year
1975
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
471
iCite
Relative citation ratio, by iCite
11.2
iCite
Revised in PubMed
2019-05-08
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Shearer GMG M
2Rehn TGT G
3Garbarino CAC A

Source PubMed

Topics18

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Histocompatibility AntigensMajor topic
Immunity, CellularMajor topic
LymphocytesMajor topic
Animals
Cell Membrane
Cells, Cultured
Chromium Radioisotopes
Cytotoxicity Tests, Immunologic
Epitopes
Genetics
Haptens
Isoantigens
Male
Mice
Mice, Inbred Strains
Spleen
T-Lymphocytes
Trinitrobenzenesulfonic Acid

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References30

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,547,153Cell-mediated cytotoxicity to trinitrophenyl-modified syngeneic lymphocytes.Eur J Immunol1974https://conductscience.org/library/papers/4547153PubMed
24,547,543Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytic choriomeningitis.Nature1974https://conductscience.org/library/papers/4547543PubMed
347,219The H-2 major histocompatibility complex and the I immune response region: genetic variation, function, and organization.Adv Immunol1975https://conductscience.org/library/papers/47219PubMed
44,781,392Ir-LDHB: map position and functional analysis.Eur J Immunol1973https://conductscience.org/library/papers/4781392PubMed
54,825,243Genetic control of the immune response to staphylococcal nuclease. I. Ir-Nase: control of the antibody response to nuclease by the Ir region of the mouse H-2 complex.J Exp Med1974https://conductscience.org/library/papers/4825243PubMed
64,881,822The H-2 locus of the mouse: observations and speculations concerning its comparative genetics and its polymorphism.Folia Biol (Praha)1968https://conductscience.org/library/papers/4881822PubMed
74,908,392Genetic control of specific immune responses.Adv Immunol1969https://conductscience.org/library/papers/4908392PubMed
85,277,103Enhanced immunogenicity of chemically-coated syngeneic tumor cells.Proc Natl Acad Sci U S A1971https://conductscience.org/library/papers/5277103PubMed
95,513,502Quantitative in vitro assay of cytotoxic cellular immunity.J Natl Cancer Inst1970https://conductscience.org/library/papers/5513502PubMed
105,675,436Phenotypic expressions of the major histocompatibility locus in man (HL-A): leukocyte antigens and mixed leukocyte culture reactivity.J Exp Med1968https://conductscience.org/library/papers/5675436PubMed

1 to 10 of 30

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Cited by51

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 471 citations.

PMIDTitleJournalYearIn PapersSource
21,302,087Detection of two allotype-(Ig-1)-linked minor histocompatibility loci by the use ofH-2-restricted cytotoxic lymphocytes in congenic mice.Immunogenetics1978https://conductscience.org/library/papers/21302087PubMed
10,516,727Protective immunization against melanoma by gp100 DNA-HVJ-liposome vaccine.Gene Ther1999https://conductscience.org/library/papers/10516727PubMed
7,461,728H-2 expression by lymphoid cells of different mouse strains: quantitative interaction of H-2 with monoclonal antibodies and their Fab fragments.Immunology1981https://conductscience.org/library/papers/7461728PubMed
7,419,247Immune response to acute virus infection in the Syrian hamster. I. Studies on genetic restriction of cell-mediated cytotoxicity.Immunogenetics1980https://conductscience.org/library/papers/7419247PubMed
6,979,047Tolerance of thymic cytotoxic T lymphocytes to allogeneic H-2 determinants encountered prethymically: evidence for expression of anti-H-2 receptors prior to entry into the thymus.Proc Natl Acad Sci U S A1982https://conductscience.org/library/papers/6979047PubMed
6,976,318H-2-Restricted lethal graft-versus-host diseases.Immunogenetics1981https://conductscience.org/library/papers/6976318PubMed
6,970,297[Follow-up study on antibody dependent cell-mediated cytotoxicity and cell-mediated cytotoxicity to HBs-antigen conjugated target cells in patients with hepatitis B (author's transl)].Klin Wochenschr1980https://conductscience.org/library/papers/6970297PubMed
6,967,857Functional studies of the products of H-2L locus.Immunogenetics1980https://conductscience.org/library/papers/6967857PubMed
6,955,277I-A subregion control of the transfer of delayed type hypersensitivity (DTH).Immunogenetics1982https://conductscience.org/library/papers/6955277PubMed
6,797,935Lymphocyte-mediated cytotoxicity against allogeneic tumour cells. IV. Fine specificity mapping and characterization of concanavalin A-activated cytotoxic effector lymphocytes.Immunology1981https://conductscience.org/library/papers/6797935PubMed

1 to 10 of 51

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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