Paper · 50851

Immunity to murine sarcoma virus induced tumours. IV. Direct cellular cytolysis of 51Cr labelled target cells in vitro and analysis of blocking factors which modulate cytotoxicity.

Gorczynski RM and 1 other. Br J Cancer, 1975. Cited by 48 papers, by iCite.

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ConductScience Library. Immunity to murine sarcoma virus induced tumours. IV. Direct cellular cytolysis of 51Cr labelled target cells in vitro and analysis of blocking factors which modulate cytotoxicity. Papers, record 50851. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/50851

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Immunity to murine sarcoma virus induced tumours. IV. Direct cellular cytolysis of 51Cr labelled target cells in vitro and analysis of blocking factors which modulate cytotoxicity.; PubMed
Journal: Br J Cancer; PubMed
Year: 1975; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/50851/; PubMed
DOI: https://doi.org/10.1038/bjc.1975.78; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2009458/; PubMed
The journal: https://conductscience.org/library/journal-index/0370635; PubMed
Citations, by iCite: 48; iCite
Relative citation ratio, by iCite: 1.4; iCite
Revised in PubMed: 2019-05-15; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Gorczynski RM	R M
2	Knight RA	R A

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Gammaretrovirus	Major topic
Immunity, Cellular	Major topic
Neoplasms, Experimental	Major topic
Sarcoma Viruses, Murine	Major topic
Animals
Antigens, Neoplasm
Antigens, Viral
Cytotoxicity Tests, Immunologic
Epitopes
Lymphoma
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Spleen
T-Lymphocytes
Time Factors

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References24

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	4,360,545	Evidence for in vivo protection against murine-sarcoma virus-induced tumors by T lymphocytes from immune animals.	J Immunol	1974	https://conductscience.org/library/papers/4360545	PubMed
2	4,191,812	The role of immunoglobulins in lymphocyte-mediated cell damage, in vitro. I. Comparison of the effects of target cell specific antibody and normal serum factors on cellular damage by immune and non-immune lymphocytes.	Immunology	1970	https://conductscience.org/library/papers/4191812	PubMed
3	4,361,978	Immunity to murine sarcoma virus-inducted tumors. II. Suppression of T cell-mediated immunity by cells from progressor animals.	J Immunol	1974	https://conductscience.org/library/papers/4361978	PubMed
5	4,110,282	Cell-surface antigens induced by avian RNA tumor viruses: detection by immunoferritin technique.	Virology	1972	https://conductscience.org/library/papers/4110282	PubMed
6	4,117,188	In vitro cytotoxicity by a nonthymus-processed lymphocyte population with specificity for a virally determined tumor cell surface antigen.	J Exp Med	1972	https://conductscience.org/library/papers/4117188	PubMed
7	4,122,415	Immunogenic properties of solubilized tumour antigen from an RNA virus-transformed neoplasm.	Nature	1973	https://conductscience.org/library/papers/4122415	PubMed
8	4,131,513	Common cell surface antigen associated with mammalian C-type RNA viruses. Cell membrane-bound gs antigen.	J Exp Med	1974	https://conductscience.org/library/papers/4131513	PubMed
9	5,783,244	Separation of cells by velocity sedimentation.	J Cell Physiol	1969	https://conductscience.org/library/papers/5783244	PubMed
10	4,333,737	Cell-surface antigens induced by avian RNA tumor viruses: detection by a cytotoxic microassay.	Virology	1972	https://conductscience.org/library/papers/4333737	PubMed
11	4,341,440	A classification of the murine leukemia viruses. Neutralization of pseudotypes of Friend spleen focus-forming virus by type-specific murine antisera.	J Exp Med	1972	https://conductscience.org/library/papers/4341440	PubMed

1 to 10 of 24

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Cited by5

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 48 citations.

PMID	Title	Journal	Year	In Papers	Source
7,459,234	Inhibition of cell proliferation rather than of cell lysis as a measure of immune reactivity in embryo-antigen-challenged mice.	Br J Cancer	1981	https://conductscience.org/library/papers/7459234	PubMed
6,186,519	Suppressor mechanisms in tumor immunity.	Experientia	1983	https://conductscience.org/library/papers/6186519	PubMed
1,084,814	The effect of cyclophosphamide and irradiation on cells which suppress contact sensitivity in the mouse.	Clin Exp Immunol	1976	https://conductscience.org/library/papers/1084814	PubMed
977,034	Autoreactivity developing spontaneously in cultured mouse spleen cells. I. Evidence that cytotoxicity is directed against embryo-associated antigen.	Immunology	1976	https://conductscience.org/library/papers/977034	PubMed
50,852	Studies on mouse Moloney virus induced tumours: I. The detection of p30 as a cytotoxic target on murine Moloney leukaemic spleen cells, and on an in vitro Moloney sarcoma line by antibody mediated cytotoxicity.	Br J Cancer	1975	https://conductscience.org/library/papers/50852	PubMed

Genes0

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None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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