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Paper · 977034

Autoreactivity developing spontaneously in cultured mouse spleen cells. I. Evidence that cytotoxicity is directed against embryo-associated antigen.

Gorczynski RM. Immunology, 1976. Cited by 16 papers, by iCite.

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ConductScience Library. Autoreactivity developing spontaneously in cultured mouse spleen cells. I. Evidence that cytotoxicity is directed against embryo-associated antigen. Papers, record 977034. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/977034

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Autoreactivity developing spontaneously in cultured mouse spleen cells. I. Evidence that cytotoxicity is directed against embryo-associated antigen.
PubMed
Journal
Immunology
PubMed
Year
1976
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
16
iCite
Relative citation ratio, by iCite
0.47
iCite
Revised in PubMed
2018-11-13
PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Gorczynski RMR M

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Embryo, MammalianMajor topic
SpleenMajor topic
Animals
Antigens
Cells, Cultured
Cytotoxicity Tests, Immunologic
Dose-Response Relationship, Immunologic
Female
Fibroblasts
Histocompatibility
Lymphocyte Activation
Male
Mice
Mice, Inbred C3H
Mice, Inbred Strains

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References13

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
15,437,620A microassay for cell-mediated immunity.Transplantation1970https://conductscience.org/library/papers/5437620PubMed
25,706,694An extension of the 51Cr-release assay for the estimation of mouse cytotoxins.Transplantation1968https://conductscience.org/library/papers/5706694PubMed
34,192,376Skin-reactive soluble antigen from intestinal cancer-cell-membranes and relationship to carcinoembryonic antigens.Lancet1970https://conductscience.org/library/papers/4192376PubMed
44,367,698Embryonic antigen expression on experimental rat tumours.Transplant Rev1974https://conductscience.org/library/papers/4367698PubMed
54,219,591Quantitative analysis of the 51Cr release cytotoxicity assay for cytotoxic lymphocytes.Cell Immunol1974https://conductscience.org/library/papers/4219591PubMed
650,851Immunity to murine sarcoma virus induced tumours. IV. Direct cellular cytolysis of 51Cr labelled target cells in vitro and analysis of blocking factors which modulate cytotoxicity.Br J Cancer1975https://conductscience.org/library/papers/50851PubMed
75,547,058Rejection of tumor allografts by mouse spleen cells sensitized in vitro.J Exp Med1971https://conductscience.org/library/papers/5547058PubMed
84,953,873Specific carcinoembryonic antigens of the human digestive system.J Exp Med1965https://conductscience.org/library/papers/4953873PubMed
95,317,482Identification by density separation of antigen-specific surface receptors on the progenitors of antibody-producing cells.Immunology1971https://conductscience.org/library/papers/5317482PubMed
10806,353Cell-mediated immunity to Murine tumor allografts. Increase in the activities of activated thymus-derived cells following in vitro incubation.Cell Immunol1975https://conductscience.org/library/papers/806353PubMed

Cited by5

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 16 citations.

PMIDTitleJournalYearIn PapersSource
7,459,234Inhibition of cell proliferation rather than of cell lysis as a measure of immune reactivity in embryo-antigen-challenged mice.Br J Cancer1981https://conductscience.org/library/papers/7459234PubMed
6,254,364Viral myocarditis. A review.Am J Pathol1980https://conductscience.org/library/papers/6254364PubMed
1,086,287Autoreactivity developing spontaneously in cultured mouse spleen cells. III. Inhibition of anti-embryo cytotoxicity in male T lymphocytes by female non-T cells.Immunology1976https://conductscience.org/library/papers/1086287PubMed
789,230Autoreactivity developing spontaneously in cultured mouse spleen cells. II. Comparison of cytotoxicity of cultured male and female spleen cells.Immunology1976https://conductscience.org/library/papers/789230PubMed
656,306Response of tumour-related and normal lymphocytes to antigens on fibroblasts from embryos of varying age.Br J Cancer1978https://conductscience.org/library/papers/656306PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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