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Paper508553

Pharmacokinetics of metoclopramide intravenously and orally determined by liquid chromatography.

Graffner C and 3 others. Br J Clin Pharmacol, 1979. Cited by 82 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Pharmacokinetics of metoclopramide intravenously and orally determined by liquid chromatography. Papers, record 508553. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/508553

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Pharmacokinetics of metoclopramide intravenously and orally determined by liquid chromatography.
PubMed
Journal
Br J Clin Pharmacol
PubMed
Year
1979
PubMed
Publication types
Clinical Trial, Journal Article, Randomized Controlled Trial
PubMed
Citations, by iCite
82
iCite
Relative citation ratio, by iCite
5.14
iCite
Revised in PubMed
2019-05-09
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Graffner CC
2Lagerström POP O
3Lundborg PP
4Rönn OO

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
MetoclopramideMajor topic
Administration, Oral
Adult
Chromatography, Liquid
Half-Life
Humans
Infusions, Parenteral
Kinetics
Male
Time Factors

Source PubMed

References10

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
1728,283Pharmacokinetic and concentration-effect studies with intravenous metoclopramide.Br J Clin Pharmacol1978https://conductscience.org/library/papers/728283PubMed
284,196Pharmacokinetics of metoclopramide.Lancet1979https://conductscience.org/library/papers/84196PubMed
3620,205Tardive dyskinesia associated with metoclopramide.Br Med J1978https://conductscience.org/library/papers/620205PubMed
4915,740Metoclopramide metabolism and determination by high-pressure liquid chromatography.J Pharm Sci1977https://conductscience.org/library/papers/915740PubMed
5911,636Pharmacokinetic and concentration-effect studies with metoclopramide [proceedings].Br J Clin Pharmacol1977https://conductscience.org/library/papers/911636PubMed
6786,607Metoclopramide: a review of its pharmacological properties and clinical use.Drugs1976https://conductscience.org/library/papers/786607PubMed
76,647The absorption and elimination of metoclopramide in three animal species.J Pharm Pharmacol1976https://conductscience.org/library/papers/6647PubMed
8134,142CSTRIP, a fortran IV computer program for obtaining initial polyexponential parameter estimates.J Pharm Sci1976https://conductscience.org/library/papers/134142PubMed
9767,194The effect of oral and intravenous metoclopramide on human lower esophageal sphincter pressure.Gastroenterology1976https://conductscience.org/library/papers/767194PubMed
105,411,325Assessment of pharmacokinetic constants from postinfusion blood curves obtained after I.V. infusion.J Pharm Sci1970https://conductscience.org/library/papers/5411325PubMed

Cited by29

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 82 citations.

PMIDTitleJournalYearIn PapersSource
39,487,461Metoclopramide for analgesia in renal colic: a narrative systematic review.BMC Urol2024https://conductscience.org/library/papers/39487461PubMed
35,473,697Acquired long QT syndrome due to antiemetics, COVID-19 and Blastocystis hominis induced exacerbation of congenital chloride losing diarrhoea.BMJ Case Rep2022https://conductscience.org/library/papers/35473697PubMed
35,004,534Intravenous Metoclopramide to Improve the Success Rate of Blind Bedside Post-pyloric Placement of Feeding Tube in Critically Ill Children: A Randomized, Double-Blind, Placebo-Controlled Study.Front Pediatr2021https://conductscience.org/library/papers/35004534PubMed
33,559,045Influence of Cation Transporters (OCTs and MATEs) on the Renal and Hepatobiliary Disposition of [11C]Metoclopramide in Mice.Pharm Res2021https://conductscience.org/library/papers/33559045PubMed
31,507,424Metoclopramide-Induced Acute Dystonic Reactions May Be Associated With the CYP2D6 Poor Metabolizer Status and Pregnancy-Related Hormonal Changes.Front Pharmacol2019https://conductscience.org/library/papers/31507424PubMed
29,853,808Positron Emission Tomography Imaging Reveals an Importance of Saturable Liver Uptake Transport for the Pharmacokinetics of Metoclopramide.Contrast Media Mol Imaging2018https://conductscience.org/library/papers/29853808PubMed
24,277,185High pressure liquid chromatographic analysis of metoclopramide in serum.Pharm Res1984https://conductscience.org/library/papers/24277185PubMed
8,934,580Risks and benefits of drugs used in the management of postoperative nausea and vomiting.Drug Saf1996https://conductscience.org/library/papers/8934580PubMed
7,378,253The pharmacokinetics of metoclopramide in man with observations in the dog.Br J Clin Pharmacol1980https://conductscience.org/library/papers/7378253PubMed
7,286,058Single-dose pharmacokinetics of metoclopramide.Eur J Clin Pharmacol1981https://conductscience.org/library/papers/7286058PubMed
7,250,177The pharmacokinetics of single doses of metoclopramide in renal failure.Eur J Clin Pharmacol1981https://conductscience.org/library/papers/7250177PubMed
6,860,530Dystonic reactions and the pharmacokinetics of metoclopramide in children.Br J Clin Pharmacol1983https://conductscience.org/library/papers/6860530PubMed
6,691,890Effects of migraine attack and metoclopramide on the absorption of tolfenamic acid.Br J Clin Pharmacol1984https://conductscience.org/library/papers/6691890PubMed
6,662,181Metoclopramide and breast feeding: transfer into milk and the newborn.Eur J Clin Pharmacol1983https://conductscience.org/library/papers/6662181PubMed
6,626,428High dose metoclopramide-preliminary pharmacokinetic studies.Br J Clin Pharmacol1983https://conductscience.org/library/papers/6626428PubMed
6,617,723Continuous infusion of high-dose metoclopramide for the prevention of nausea and vomiting in patients receiving cancer chemotherapy.Eur J Clin Pharmacol1983https://conductscience.org/library/papers/6617723PubMed
6,508,977Pharmacokinetics and efficacy of high-dose metoclopramide given by continuous infusion for the control of cytotoxic drug-induced vomiting.Br J Clin Pharmacol1984https://conductscience.org/library/papers/6508977PubMed
6,407,846Placental transfer and hormonal effects of metoclopramide.Eur J Clin Pharmacol1983https://conductscience.org/library/papers/6407846PubMed
6,360,466Clinical pharmacokinetics of metoclopramide.Clin Pharmacokinet1983https://conductscience.org/library/papers/6360466PubMed
6,345,129Metoclopramide. An updated review of its pharmacological properties and clinical use.Drugs1983https://conductscience.org/library/papers/6345129PubMed

See all 29 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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