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Paper · 52685

Bifunctional major histocompatibility-linked genetic regulation of cell-mediated lympholysis to trinitrophenyl-modified autologous lymphocytes.

Schmitt-Verhulst AM and 1 other. J Exp Med, 1975. Cited by 76 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Bifunctional major histocompatibility-linked genetic regulation of cell-mediated lympholysis to trinitrophenyl-modified autologous lymphocytes. Papers, record 52685. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/52685

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Bifunctional major histocompatibility-linked genetic regulation of cell-mediated lympholysis to trinitrophenyl-modified autologous lymphocytes.
PubMed
Journal
J Exp Med
PubMed
Year
1975
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
76
iCite
Relative citation ratio, by iCite
1.72
iCite
Revised in PubMed
2019-05-08
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Schmitt-Verhulst AMA M
2Shearer GMG M

Source PubMed

Topics17

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
GenesMajor topic
HistocompatibilityMajor topic
Immunity, CellularMajor topic
T-LymphocytesMajor topic
Alleles
Animals
Autoantigens
Cytotoxicity Tests, Immunologic
Epitopes
Genes, Regulator
Genetic Linkage
Lymphocyte Culture Test, Mixed
Male
Mice
Nitrophenols
Spleen
Trinitrobenzenesulfonic Acid

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References20

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,079,922Lysis mediated by T cells and restricted by H-2 antigen of target cells infected with vaccinia virus.Nature1975https://conductscience.org/library/papers/1079922PubMed
21,086,219Cell-medicated cytotoxicity against ectromelia virus-infected target cells. III. Role of the H-2 gene complex.Eur J Immunol1975https://conductscience.org/library/papers/1086219PubMed
3123,002H-2 compatibility is required for T-cell-mediated lysis of target cells infected with lymphocytic choriomeningitis virus.J Exp Med1975https://conductscience.org/library/papers/123002PubMed
44,108,876The H-2 model for the major histocompatibility systems.Transplant Rev1971https://conductscience.org/library/papers/4108876PubMed
54,128,439A mouse B-cell alloantigen determined by gene(s) linked to the major histocompatibility complex.J Exp Med1973https://conductscience.org/library/papers/4128439PubMed
64,133,807Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system.Nature1974https://conductscience.org/library/papers/4133807PubMed
74,134,154HL-A, immune-response genes, and disease.Lancet1974https://conductscience.org/library/papers/4134154PubMed
84,136,175Antigen-specific thymus cell factors in the genetic control of the immune response to poly-(tyrosyl, glutamyl)-poly-D, L-alanyl--poly-lysyl.J Exp Med1974https://conductscience.org/library/papers/4136175PubMed
94,204,563Autoimmune murine thyroiditis. IV. Localization of genetic control of the immune response.J Immunol1974https://conductscience.org/library/papers/4204563PubMed
104,215,740The genetic control of T cell-meditated immunity. I. Characterization of a mouse strain whose low responsiveness is inherited as a recessive trait.Immunology1974https://conductscience.org/library/papers/4215740PubMed

Cited by31

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 76 citations.

PMIDTitleJournalYearIn PapersSource
30,687,803Peter Doherty, Nobel Laureate: Questions and Reflections Concerning MHC Restriction and other Fruits of a Life of Biomedical Erudition.Pathog Immun2018https://conductscience.org/library/papers/30687803PubMed
7,025,308HLA restriction of human cytotoxic T cells.Springer Semin Immunopathol1980https://conductscience.org/library/papers/7025308PubMed
6,972,996Major histocompatibility complex restriction of soluble helper molecules in T cell responses to altered self.J Exp Med1981https://conductscience.org/library/papers/6972996PubMed
6,932,473Selective turnover and shedding of H-2K and H-2D antigens is controlled by the major histocompatibility complex. Implications for H-2-restricted recognition.J Exp Med1980https://conductscience.org/library/papers/6932473PubMed
6,610,062
Virus specificity of cytotoxic T lymphocytes generated during acute lymphocytic choriomeningitis virus infection: role of the H-2 region in determining cross-reactivity for different lymphocytic choriomeningitis virus strains.
J Virol1984https://conductscience.org/library/papers/6610062PubMed
6,600,441Recognition and lysis of altered-self cells by macrophages. I. Modification of target cells by 2,4,6-trinitrobenzene sulphonic acid.Immunology1983https://conductscience.org/library/papers/6600441PubMed
6,444,234Role of self carriers in the immune response and tolerance. V. Reversal of trinitrophenyl-modified self suppression of the B-cell response by blocking of H-2 antigens.J Exp Med1980https://conductscience.org/library/papers/6444234PubMed
6,425,221Role of the H-2s haplotype in survival of mice after infection with Trypanosoma cruzi.Infect Immun1984https://conductscience.org/library/papers/6425221PubMed
6,219,064Mouse immunoglobulin isotypes mediating cytotoxicity of target cells by eosinophils and neutrophils.Immunology1983https://conductscience.org/library/papers/6219064PubMed
6,201,586Trinitrophenyl modification of H-2k and H-2b spleen cells results in enhanced serological detection of Kk-like determinants.J Exp Med1984https://conductscience.org/library/papers/6201586PubMed

1 to 10 of 31

See all 31 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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