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Paper53265

Induction of cytotoxic T lymphocytes against I-region-coded determinants: in vitro evidence for a third histocompatibility locus in the mouse.

Wagner H and 3 others. J Exp Med, 1975. Cited by 126 papers, by iCite.

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ConductScience Library. Induction of cytotoxic T lymphocytes against I-region-coded determinants: in vitro evidence for a third histocompatibility locus in the mouse. Papers, record 53265. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/53265

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Induction of cytotoxic T lymphocytes against I-region-coded determinants: in vitro evidence for a third histocompatibility locus in the mouse.
PubMed
Journal
J Exp Med
PubMed
Year
1975
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
126
iCite
Relative citation ratio, by iCite
2.22
iCite
Revised in PubMed
2019-05-08
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Wagner HH
2Götze DD
3Ptschelinzew LL
4Röllinghoff MM

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
EpitopesMajor topic
T-LymphocytesMajor topic
Animals
Antigen-Antibody Reactions
Concanavalin A
Histocompatibility Antigens
Hybridization, Genetic
Lectins
Lipopolysaccharides
Lymphocyte Activation
Lymphocyte Culture Test, Mixed
Mice
Mice, Inbred Strains
Species Specificity

Source PubMed

References29

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,119,632T-cell mediated immunity in vitro: an analysis of antigen recognition and target cell lysis.Transplant Rev1972https://conductscience.org/library/papers/4119632PubMed
24,130,060Demonstration by MLR test of a previously unsuspected intra-H-2 crossover in the B10.HTT strain: implications concerning location of MLR determinants in the Ir region.Transplant Proc1973https://conductscience.org/library/papers/4130060PubMed
34,130,075The specificty and the activation mechanism of cell-mediated lympholysis (CML) in man.Transplant Proc1973https://conductscience.org/library/papers/4130075PubMed
44,138,069Role of H-2 lymphocyte-defined and serologically-defined components in the generation of cytotoxic lymphocytes.J Exp Med1974https://conductscience.org/library/papers/4138069PubMed
54,139,231Genetic control of cell-mediated lympholysis in mouse.J Exp Med1974https://conductscience.org/library/papers/4139231PubMed
64,143,965Allograft response in vitro.Transplant Rev1972https://conductscience.org/library/papers/4143965PubMed
74,147,577Serologic evidence for antigens controlled by the Ir region in mice.J Exp Med1973https://conductscience.org/library/papers/4147577PubMed
84,151,339Cell-mediated cytotoxicity, allograft rejection, and tumor immunity.Adv Immunol1974https://conductscience.org/library/papers/4151339PubMed
94,151,904T-cell-mediated immune responses induced in vitro: a probe for allograft and tumor immunity.Transplant Rev1973https://conductscience.org/library/papers/4151904PubMed
104,153,771I-region genes are expressed on T and B lymphocytes. Studies of the mixed lymphocyte reaction (MLR).J Exp Med1974https://conductscience.org/library/papers/4153771PubMed
114,199,283Cell-mediated immune responses in vitro: interaction of thymus-derived cells during cytotoxic allograft responses in vitro.Science1973https://conductscience.org/library/papers/4199283PubMed
124,267,208Cell-mediated lympholysis. Importance of serologically defined H-2 regions.J Exp Med1973https://conductscience.org/library/papers/4267208PubMed
134,271,348Antigenic strength investigated by cell-mediated lympholysis in mice.Eur J Immunol1973https://conductscience.org/library/papers/4271348PubMed
144,272,823The involvement of LD- and SD-region differences in MLC and CML: a three-cell experiment.Transplant Proc1973https://conductscience.org/library/papers/4272823PubMed
154,277,395Cell-mediated cell lysis in vitro: genetic control of killer cell production and target specificities in the mouse.Eur J Immunol1974https://conductscience.org/library/papers/4277395PubMed
164,278,108Generation of cytotoxic T lymphocytes in vitro. I. Response of normal and immune mouse spleen cells in mixed leukocyte cultures.J Exp Med1974https://conductscience.org/library/papers/4278108PubMed
174,404,878Serologically defined and lymphocyte-defined components of the major histocompatibility complex in the mouse.J Exp Med1972https://conductscience.org/library/papers/4404878PubMed
184,424,981Tla types of H-2 congenic and recombinant mice.Transplantation1974https://conductscience.org/library/papers/4424981PubMed
194,517,664New lymphocyte antigen system (Lna) controlled by the Ir region of the mouse H-2 complex.Proc Natl Acad Sci U S A1973https://conductscience.org/library/papers/4517664PubMed
204,541,239Serological identification of an Ir-region product.Science1973https://conductscience.org/library/papers/4541239PubMed

See all 29 references

Cited by39

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 126 citations.

PMIDTitleJournalYearIn PapersSource
39,874,005Impaired Granularity in T cell Subsets but not in B cell Favors the Carcinogenesis of the Breast: A Preliminary Study in Indonesian Women Cohort.Asian Pac J Cancer Prev2025https://conductscience.org/library/papers/39874005PubMed
38,515,134CTLs heterogeneity and plasticity: implications for cancer immunotherapy.Mol Cancer2024https://conductscience.org/library/papers/38515134PubMed
37,654,482Cytotoxic CD4 T cells in the mucosa and in cancer.Front Immunol2023https://conductscience.org/library/papers/37654482PubMed
36,389,159CTLs: Killers of intracellular bacteria.Front Cell Infect Microbiol2022https://conductscience.org/library/papers/36389159PubMed
36,107,855T-cell receptor variable region usage in Chagas disease: A systematic review of experimental and human studies.PLoS Negl Trop Dis2022https://conductscience.org/library/papers/36107855PubMed
32,674,488Harnessing the Complete Repertoire of Conventional Dendritic Cell Functions for Cancer Immunotherapy.Pharmaceutics2020https://conductscience.org/library/papers/32674488PubMed
28,280,496CD4 CTL, a Cytotoxic Subset of CD4+ T Cells, Their Differentiation and Function.Front Immunol2017https://conductscience.org/library/papers/28280496PubMed
6,980,828Cytolytic T cells activated by H-2-controlled E molecules cross-react with A molecules.Immunogenetics1982https://conductscience.org/library/papers/6980828PubMed
6,980,419Long-term human cytolytic T-cell lines allospecific for HLA-DR6 antigen are OKT4+.Proc Natl Acad Sci U S A1982https://conductscience.org/library/papers/6980419PubMed
6,975,943Significance of Lyt phenotypes: Lyt2 antibodies block activities of T cells that recognize class 1 major histocompatibility complex antigens regardless of their function.Proc Natl Acad Sci U S A1981https://conductscience.org/library/papers/6975943PubMed
6,971,252Receptor specificity, functional characteristics, and cell-surface phenotype of a highly selected anti-I-Ab-specific, long-term T-cell line.Immunogenetics1981https://conductscience.org/library/papers/6971252PubMed
6,967,856Cell-mediated cytotoxicity against HLA-D-region products expressed in monocytes and B lymphocytes. II. HLA-A- or B-antigen compatibility is not required for HLA-D-region directed cytotoxicity.Immunogenetics1980https://conductscience.org/library/papers/6967856PubMed
6,966,608Induction of cytotoxic peritoneal exudate cells by T-cell immune adjuvants of the beta(1 leads to 3) glucan-type lentinan and its analogues.Immunology1980https://conductscience.org/library/papers/6966608PubMed
6,459,997Generation of cytotoxic T lymphocytes by the H-2-encoded E molecules.Immunogenetics1981https://conductscience.org/library/papers/6459997PubMed
6,454,744
Enhancement of T lymphocyte functions by Fc fragments of immunoglobulins. I. Augmentation of allogeneic mixed lymphocyte culture reactions requires I-A- or I-B-subregion differences between effector and stimulator cell populations.
J Exp Med1981https://conductscience.org/library/papers/6454744PubMed
6,242,889Expression of the I-E target antigen for T-cell killing requires two genes.Immunogenetics1980https://conductscience.org/library/papers/6242889PubMed
6,201,440Antigen-specific helper T cells recognize determinants encoded in the H-2D region of the H-2 gene complex.Immunogenetics1984https://conductscience.org/library/papers/6201440PubMed
6,157,642Cell-mediated cytotoxicity against HLA-D-region products expressed in monocytes and B lymphocytes. I. Blocking by Unlabelled cells and inhibition by antisera.Immunogenetics1980https://conductscience.org/library/papers/6157642PubMed
3,485,173Differences in antigen presentation to MHC class I-and class II-restricted influenza virus-specific cytolytic T lymphocyte clones.J Exp Med1986https://conductscience.org/library/papers/3485173PubMed
2,939,451T cells can be cytotoxic without making interleukin 2: a model of separate pathways of induction.Proc Natl Acad Sci U S A1986https://conductscience.org/library/papers/2939451PubMed

See all 39 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

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  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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