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Paper5430786

Studies on the origin of human leukocytic pyrogen.

Nordlund JJ and 2 others. J Exp Med, 1970. Cited by 57 papers, by iCite.

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ConductScience Library. Studies on the origin of human leukocytic pyrogen. Papers, record 5430786. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/5430786

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Studies on the origin of human leukocytic pyrogen.
PubMed
Journal
J Exp Med
PubMed
Year
1970
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
57
iCite
Relative citation ratio, by iCite
1.8
iCite
Revised in PubMed
2019-05-08
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Nordlund JJJ J
2Root RKR K
3Wolff SMS M

Source PubMed

Topics19

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
LeukocytesMajor topic
PyrogensMajor topic
Animals
Carbon Isotopes
Cyanides
Cycloheximide
Dactinomycin
Endotoxins
Fluorides
Glycolysis
Humans
Phagocytosis
Protein Biosynthesis
Proteins
Puromycin
RNA, Messenger
Rabbits
Staphylococcus
Vincristine

Source PubMed

References32

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
15,222,583Ribonucleic acid biosynthesis in human leukocytes. Effects of phagocytosis on RNA metabolism.Blood1966https://conductscience.org/library/papers/5222583PubMed
214,453,158Studies on the pathogenesis of fever. X. The effect of certain enzyme inhibitors on the production and activity of leucocvtic pvrogen.J Exp Med1962https://conductscience.org/library/papers/14453158PubMed
35,937,057Studies on the pathogenesis of fever. XIV. Further observations on the chemistry of leukocytic pyrogen.J Exp Med1966https://conductscience.org/library/papers/5937057PubMed
45,967,193Energy requirement for the incorporation of amino acids into protein of isolated mouse-liver mitochondria.J Cell Physiol1966https://conductscience.org/library/papers/5967193PubMed
54,902,892Studies on the pathogenesis of fever. 18. Activation of leukocytes for pyrogen production.J Exp Med1970https://conductscience.org/library/papers/4902892PubMed
616,695,933Studies on steroid fever: I. Production of leukocyte pyrogen in vitro by etiocholanolone.J Clin Invest1968https://conductscience.org/library/papers/16695933PubMed
75,698,483The mechanism of steroid-induced fever.Ann Intern Med1968https://conductscience.org/library/papers/5698483PubMed
813,654,378The biochemical basis of phagocytosis. I. Metabolic changes during the ingestion of particles by polymorphonuclear leukocytes.J Biol Chem1959https://conductscience.org/library/papers/13654378PubMed
914,166,766PUROMYCIN INHIBITION OF PROTEIN SYNTHESIS: INCORPORATION OF PUROMYCIN INTO PEPTIDE CHAINS.Proc Natl Acad Sci U S A1964https://conductscience.org/library/papers/14166766PubMed
105,935,620Human leukocyte pyrogen producing fever in rabbits.Proc Soc Exp Biol Med1966https://conductscience.org/library/papers/5935620PubMed
115,927,898Pyrogenicity of granulocyte lysosomes.Am J Physiol1966https://conductscience.org/library/papers/5927898PubMed
1213,739,105Studies on the pathogenesis of fever. VII. Preliminary chemical characterization of leucocytic pyrogen.J Exp Med1960https://conductscience.org/library/papers/13739105PubMed
135,634,629Effect of vincristine on synthesis of ribonucleic acid and protein in leukaemic leucocytes.Br J Haematol1968https://conductscience.org/library/papers/5634629PubMed
1413,699,218Observations on the production of pyrogenic substances by rabbit and human leucocytes.J Exp Med1961https://conductscience.org/library/papers/13699218PubMed
1514,220,690BIOCHEMICAL EFFECTS OF THE VINCA ALKALOIDS. II. A COMPARISON OF THE EFFECTS OF COLCHICINE, VINBLASTINE AND VINCRISTINE ON THE SYNTHESIS OF RIBONUCLEIC ACIDS IN EHRLICH ASCITES CARCINOMA CELLS.Biochim Biophys Acta1964https://conductscience.org/library/papers/14220690PubMed
165,764,029Leukocyte preservation. I. Phagocytic stimulation of the hexose monophosphate shunt as a measure of cell viability.J Lab Clin Med1969https://conductscience.org/library/papers/5764029PubMed
176,079,946Effect of inhibitors of protein synthesis on pyrogen production by granulocytes.Proc Soc Exp Biol Med1967https://conductscience.org/library/papers/6079946PubMed
184,863,132An assay method for leukocyte pyrogen.J Exp Med1967https://conductscience.org/library/papers/4863132PubMed
1914,322,026QUANTITATIVE STUDIES OF FEBRILE TOLERANCE AND LEVELS OF SPECIFIC ANTIBODY EVOKED BY BACTERIAL ENDOTOXIN.J Clin Invest1965https://conductscience.org/library/papers/14322026PubMed
206,023,867Interactions of gram-negative bacterial endotoxin with rabbit blood in vitro.Am J Physiol1967https://conductscience.org/library/papers/6023867PubMed

See all 32 references

Cited by22

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 57 citations.

PMIDTitleJournalYearIn PapersSource
7,085,045Studies on the active site of human leukocytic pyrogen.Inflammation1982https://conductscience.org/library/papers/7085045PubMed
6,758,374Fever: its history, cause, and function.Yale J Biol Med1982https://conductscience.org/library/papers/6758374PubMed
6,750,226Production of fever and its effects on the host.Klin Wochenschr1982https://conductscience.org/library/papers/6750226PubMed
6,416,039Molecular mechanisms in endotoxin fever.Agents Actions1983https://conductscience.org/library/papers/6416039PubMed
6,404,384Hypothermia during chemotherapy for Hodgkin's disease.Br Med J (Clin Res Ed)1983https://conductscience.org/library/papers/6404384PubMed
4,829,934Demonstration and characterization of two distinct human leukocytic pyrogens.J Exp Med1974https://conductscience.org/library/papers/4829934PubMed
4,611,062Pyrogen release in vitro by lymphoid tissues from patients with Hodgkin's disease.Yale J Biol Med1974https://conductscience.org/library/papers/4611062PubMed
4,573,840Synthesis of endogenous pyrogen by rabbit leukocytes.J Exp Med1973https://conductscience.org/library/papers/4573840PubMed
4,427,091Studies on the mechanism of endogenous pyrogen production. III. Human blood monocytes.J Exp Med1974https://conductscience.org/library/papers/4427091PubMed
4,426,696Studies on the mechanism of endogenous pyrogen production. II. Role of cell products in the regulation of pyrogen release from blood leukocytes.Infect Immun1974https://conductscience.org/library/papers/4426696PubMed
3,862,287Effect of protein synthesis inhibitors on leukocytic pyrogen-induced in vitro hypothalamic prostaglandin production.Yale J Biol Med1985https://conductscience.org/library/papers/3862287PubMed
2,994,306Studies on the production of endogenous pyrogen by rabbit monocytes: the role of calcium and cyclic nucleotides.Yale J Biol Med1985https://conductscience.org/library/papers/2994306PubMed
2,437,239Heat-shock protein synthesis by human polymorphonuclear cells.J Exp Med1987https://conductscience.org/library/papers/2437239PubMed
1,262,782Colchicine stimulation of pyrogen production by human blood leukocytes.J Exp Med1976https://conductscience.org/library/papers/1262782PubMed
954,976On the mechanism of pyrogenic action of ricin.Experientia1976https://conductscience.org/library/papers/954976PubMed
762,495RNA and protein synthesis in human peripheral blood polymorphonuclear leukocytes.J Exp Med1979https://conductscience.org/library/papers/762495PubMed
559,692The production of antibody against human leukocytic pyrogen.J Clin Invest1977https://conductscience.org/library/papers/559692PubMed
552,177The Jeremiah Metzger Lecture. The pathogenesis of fever in human subjects.Trans Am Clin Climatol Assoc1980https://conductscience.org/library/papers/552177PubMed
390,356Temperature and host defense.Microbiol Rev1979https://conductscience.org/library/papers/390356PubMed
233,905Differences in pyrogen production by mononuclear phagocytes and by fibroblasts or HeLa cells.J Exp Med1977https://conductscience.org/library/papers/233905PubMed

See all 22 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

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  • ClinicalTrials.govNo license stated
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  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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