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Paper559692

The production of antibody against human leukocytic pyrogen.

Dinarello CA and 2 others. J Clin Invest, 1977. Cited by 78 papers, by iCite.

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ConductScience Library. The production of antibody against human leukocytic pyrogen. Papers, record 559692. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/559692

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The production of antibody against human leukocytic pyrogen.
PubMed
Journal
J Clin Invest
PubMed
Year
1977
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
78
iCite
Relative citation ratio, by iCite
2.19
iCite
Revised in PubMed
2018-11-13
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Dinarello CAC A
2Renfer LL
3Wolff SMS M

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antibody FormationMajor topic
LeukocytesMajor topic
PyrogensMajor topic
Animals
Antigen-Antibody Complex
Cross Reactions
Humans
Kinetics
Rabbits

Source PubMed

References16

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
114,267,252QUANTITATIVE ASPECTS OF THE PYROGENIC RESPONSE OF RABBITS TO ENDOTOXIN.J Lab Clin Med1965https://conductscience.org/library/papers/14267252PubMed
44,179,068Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.Scand J Clin Lab Invest Suppl1968https://conductscience.org/library/papers/4179068PubMed
54,829,934Demonstration and characterization of two distinct human leukocytic pyrogens.J Exp Med1974https://conductscience.org/library/papers/4829934PubMed
64,370,251Partial purification of human interferon by affinity chromatography.Proc Natl Acad Sci U S A1974https://conductscience.org/library/papers/4370251PubMed
74,621,751On the demonstration of circulating human endogenous pyrogen.Proc Soc Exp Biol Med1972https://conductscience.org/library/papers/4621751PubMed
84,550,084Fever.N Engl J Med1972https://conductscience.org/library/papers/4550084PubMed
94,550,469Bactericidal and metabolic properties of human eosinophils.Blood1972https://conductscience.org/library/papers/4550469PubMed
104,810,957Further purification of rabbit leukocyte pyrogen.J Lab Clin Med1974https://conductscience.org/library/papers/4810957PubMed
114,971,842Selective enzyme purification by affinity chromatography.Proc Natl Acad Sci U S A1968https://conductscience.org/library/papers/4971842PubMed
124,910,480Factors affecting the quantitative production and assay of human leukocytic pyrogen.J Lab Clin Med1970https://conductscience.org/library/papers/4910480PubMed
13808,582A primate model for the study of human fever.J Infect Dis1975https://conductscience.org/library/papers/808582PubMed
141,250,862Pyrogen from mouse macrophages causes fever in mice.Proc Soc Exp Biol Med1976https://conductscience.org/library/papers/1250862PubMed
155,548,524Transferable pyrogen in human experimental fever.Clin Sci1971https://conductscience.org/library/papers/5548524PubMed
165,430,786Studies on the origin of human leukocytic pyrogen.J Exp Med1970https://conductscience.org/library/papers/5430786PubMed
175,806,584The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis.J Biol Chem1969https://conductscience.org/library/papers/5806584PubMed
185,935,620Human leukocyte pyrogen producing fever in rabbits.Proc Soc Exp Biol Med1966https://conductscience.org/library/papers/5935620PubMed

Cited by20

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 78 citations.

PMIDTitleJournalYearIn PapersSource
27,226,996The history of fever, leukocytic pyrogen and interleukin-1.Temperature (Austin)2015https://conductscience.org/library/papers/27226996PubMed
7,448,120A pyrogen derived from human white cells which is active in mice.Br J Exp Pathol1980https://conductscience.org/library/papers/7448120PubMed
7,085,045Studies on the active site of human leukocytic pyrogen.Inflammation1982https://conductscience.org/library/papers/7085045PubMed
6,985,918Endogenous pyrogen production by Hodgkin's disease and human histiocytic lymphoma cell lines in vitro.J Clin Invest1980https://conductscience.org/library/papers/6985918PubMed
6,609,169Induction of human interleukin-1 by a product of Staphylococcus aureus associated with toxic shock syndrome.J Clin Invest1984https://conductscience.org/library/papers/6609169PubMed
6,454,745Demonstration of a human pyrogen-inducing factor during mixed leukocyte reactions.J Exp Med1981https://conductscience.org/library/papers/6454745PubMed
6,416,039Molecular mechanisms in endotoxin fever.Agents Actions1983https://conductscience.org/library/papers/6416039PubMed
6,358,043Effect of ibuprofen on fever and metabolic changes induced by continuous infusion of leukocytic pyrogen (interleukin 1) or endotoxin.Infect Immun1983https://conductscience.org/library/papers/6358043PubMed
6,212,597Human monocyte-derived soluble product(s) has an accessory function in the generation of histamine- and concanavalin A-induced suppressor T cells.J Clin Invest1982https://conductscience.org/library/papers/6212597PubMed
3,494,807Human interleukin 1 induces interleukin 1 gene expression in human vascular smooth muscle cells.J Exp Med1987https://conductscience.org/library/papers/3494807PubMed
3,027,706Epstein-Barr virus-containing B-cell line produces an interleukin 1 that it uses as a growth factor.Proc Natl Acad Sci U S A1987https://conductscience.org/library/papers/3027706PubMed
2,826,055Human rheumatoid synovial and normal blood dendritic cells as antigen presenting cell--comparison with autologous monocytes.Clin Exp Immunol1987https://conductscience.org/library/papers/2826055PubMed
2,431,094Human keratinocytes contain mRNA indistinguishable from monocyte interleukin 1 alpha and beta mRNA. Keratinocyte epidermal cell-derived thymocyte-activating factor is identical to interleukin 1.J Exp Med1986https://conductscience.org/library/papers/2431094PubMed
2,411,843Pretranslational modulation of acute phase hepatic protein synthesis by murine recombinant interleukin 1 (IL-1) and purified human IL-1.J Exp Med1985https://conductscience.org/library/papers/2411843PubMed
680,947A new sensitive method for detecting human endogenous (leukocyte) pyrogen.Inflammation1978https://conductscience.org/library/papers/680947PubMed
659,595Human leukocytic pyrogen induces release of specific granule contents from human neutrophils.J Clin Invest1978https://conductscience.org/library/papers/659595PubMed
552,177The Jeremiah Metzger Lecture. The pathogenesis of fever in human subjects.Trans Am Clin Climatol Assoc1980https://conductscience.org/library/papers/552177PubMed
314,491Adherent cell function in murine T-lymphocyte antigen recognition. IV. Enhancement of murine T-cell antigen recognition by human leukocytic pyrogen.J Exp Med1979https://conductscience.org/library/papers/314491PubMed
90,061Stimulation of neutrophil oxygen-dependent metabolism by human leukocytic pyrogen.J Clin Invest1979https://conductscience.org/library/papers/90061PubMed
22,079Human leukocytic pyrogen: purification and development of a radioimmunoassay.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/22079PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

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  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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