Paper659595
Human leukocytic pyrogen induces release of specific granule contents from human neutrophils.
Klempner MS and 2 others. J Clin Invest, 1978. Cited by 225 papers, by iCite.
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ConductScience Library. Human leukocytic pyrogen induces release of specific granule contents from human neutrophils. Papers, record 659595. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/659595
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Human leukocytic pyrogen induces release of specific granule contents from human neutrophils.
- PubMed
Topics12
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Neutrophils | Major topic |
| Pyrogens | Major topic |
| Cations, Divalent | |
| Cytochalasin B | |
| Humans | |
| Indomethacin | |
| Lactoferrin | |
| Leukocytes | |
| Lysosomes | |
| Muramidase | |
| Naproxen | |
| Phagocytosis |
Source PubMed
References27
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 1,151,072 | Influence of divalent cations upon complement-mediated enzyme release from human polymorphonuclear leukocytes. | J Immunol | 1975 | https://conductscience.org/library/papers/1151072 | PubMed |
| 2 | 4,891,881 | Lowering of plasma iron concentration in the rat with leukocytic extracts. | Am J Physiol | 1969 | https://conductscience.org/library/papers/4891881 | PubMed |
| 3 | 5,539,203 | Radioimmunoassay for prostaglandins. | Science | 1971 | https://conductscience.org/library/papers/5539203 | PubMed |
| 4 | 14,267,252 | QUANTITATIVE ASPECTS OF THE PYROGENIC RESPONSE OF RABBITS TO ENDOTOXIN. | J Lab Clin Med | 1965 | https://conductscience.org/library/papers/14267252 | PubMed |
| 5 | 14,453,507 | Effects of bacteria endotoxin on plasma iron. | Proc Soc Exp Biol Med | 1962 | https://conductscience.org/library/papers/14453507 | PubMed |
| 6 | 13,864,558 | [The effect of a bacterial pyrogen-pyrexal-on serum iron]. | Dtsch Arch Klin Med | 1962 | https://conductscience.org/library/papers/13864558 | PubMed |
| 8 | 22,079 | Human leukocytic pyrogen: purification and development of a radioimmunoassay. | Proc Natl Acad Sci U S A | 1977 | https://conductscience.org/library/papers/22079 | PubMed |
| 9 | 322,507 | The differential mobilization of human neutrophil granules. Effects of phorbol myristate acetate and ionophore A23187. | Am J Pathol | 1977 | https://conductscience.org/library/papers/322507 | PubMed |
| 10 | 300,882 | Possible involvement of leukocytic endogenous mediator in granulopoiesis. | Proc Soc Exp Biol Med | 1977 | https://conductscience.org/library/papers/300882 | PubMed |
| 11 | 559,692 | The production of antibody against human leukocytic pyrogen. | J Clin Invest | 1977 | https://conductscience.org/library/papers/559692 | PubMed |
| 12 | 840,859 | Comparison of leukocytic pyrogen and leukocytic endogenous mediator. | Proc Soc Exp Biol Med | 1977 | https://conductscience.org/library/papers/840859 | PubMed |
| 13 | 1,025,156 | Concanavalin A induces microtubule assembly and specific granule discharge in human polymorphonuclear leukocytes. | J Cell Biol | 1976 | https://conductscience.org/library/papers/1025156 | PubMed |
| 14 | 4,596,695 | The ability of chemotactic factors to induce lysosomal enzyme release. I. The characteristics of the release, the importance of surfaces and the relation of enzyme release to chemotactic responsiveness. | J Immunol | 1974 | https://conductscience.org/library/papers/4596695 | PubMed |
| 15 | 4,133,056 | Selective labilization of specific granules in polymorphonuclear leukocytes by phorbol myristate acetate. | Am J Pathol | 1974 | https://conductscience.org/library/papers/4133056 | PubMed |
| 16 | 4,134,220 | Character of azurophil and specific granules purified from human polymorphonuclear leukocytes. | Lab Invest | 1974 | https://conductscience.org/library/papers/4134220 | PubMed |
| 17 | 4,351,807 | Cytochalasin B: effect on lysosomal enzyme release from human leukocytes. | Proc Natl Acad Sci U S A | 1973 | https://conductscience.org/library/papers/4351807 | PubMed |
| 18 | 4,829,934 | Demonstration and characterization of two distinct human leukocytic pyrogens. | J Exp Med | 1974 | https://conductscience.org/library/papers/4829934 | PubMed |
| 19 | 4,712,831 | Lysozyme activity in human neutrophilic granulocytes. | Br J Haematol | 1973 | https://conductscience.org/library/papers/4712831 | PubMed |
| 20 | 4,355,374 | Mechanisms of lysosomal enzyme release from human leukocytes: microtubule assembly and membrane fusion induced by a component of complement. | Proc Natl Acad Sci U S A | 1973 | https://conductscience.org/library/papers/4355374 | PubMed |
| 21 | 4,215,759 | Intracellular and extracellular degranulation of human polymorphonuclear azurophil and specific granules induced by immune complexes. | Infect Immun | 1974 | https://conductscience.org/library/papers/4215759 | PubMed |
Cited by56
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 225 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,029,961 | Development of a Novel Mouse Model of Severe Acute Pancreatitis with Pathological Features Recapitulating Human Disease. | Dig Dis Sci | 2026 | https://conductscience.org/library/papers/42029961 | PubMed |
| 32,948,440 | Glycogen synthase kinase-3: A putative target to combat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. | Cytokine Growth Factor Rev | 2021 | https://conductscience.org/library/papers/32948440 | PubMed |
| 29,621,258 | DIVA metabolomics: Differentiating vaccination status following viral challenge using metabolomic profiles. | PLoS One | 2018 | https://conductscience.org/library/papers/29621258 | PubMed |
| 28,613,272 | Phage-Phagocyte Interactions and Their Implications for Phage Application as Therapeutics. | Viruses | 2017 | https://conductscience.org/library/papers/28613272 | PubMed |
| 24,271,561 | Iron and neoplasia. | Biol Trace Elem Res | 1981 | https://conductscience.org/library/papers/24271561 | PubMed |
| 9,326,155 | Does occupational exposure to iron promote infection? | Occup Environ Med | 1997 | https://conductscience.org/library/papers/9326155 | PubMed |
| 9,060,579 | Metabolic responses to interleukin-1: centrally and peripherally mediated. | Ann Surg | 1997 | https://conductscience.org/library/papers/9060579 | PubMed |
| 8,855,487 | Therapeutic modulation of free radical-mediated reperfusion injury of the liver and its surgical implications. | Surg Today | 1996 | https://conductscience.org/library/papers/8855487 | PubMed |
| 8,500,890 | Effects of Listeria monocytogenes and Yersinia enterocolitica on cytokine gene expression and release from human polymorphonuclear granulocytes and epithelial (HEp-2) cells. | Infect Immun | 1993 | https://conductscience.org/library/papers/8500890 | PubMed |
| 8,317,554 | Age-dependent basal level and induction capacity of copper-zinc and manganese superoxide dismutase and other scavenging enzyme activities in leukocytes from young and elderly adults. | Am J Pathol | 1993 | https://conductscience.org/library/papers/8317554 | PubMed |
| 8,131,699 | Gastrointestinal irritancy, antiinflammatory activity, and prostanoid inhibition in the rat. Differentiation of effects between nabumetone and etodolac. | Dig Dis Sci | 1994 | https://conductscience.org/library/papers/8131699 | PubMed |
| 7,439,989 | Role of the central nervous system in acute-phase responses to leukocytic pyrogen. | Infect Immun | 1980 | https://conductscience.org/library/papers/7439989 | PubMed |
| 7,085,045 | Studies on the active site of human leukocytic pyrogen. | Inflammation | 1982 | https://conductscience.org/library/papers/7085045 | PubMed |
| 6,862,633 | Further comparisons of endogenous pyrogens and leukocytic endogenous mediators. | Infect Immun | 1983 | https://conductscience.org/library/papers/6862633 | PubMed |
| 6,750,226 | Production of fever and its effects on the host. | Klin Wochenschr | 1982 | https://conductscience.org/library/papers/6750226 | PubMed |
| 6,608,106 | Effect of ultraviolet radiation on production of epidermal cell thymocyte-activating factor/interleukin 1 in vivo and in vitro. | Proc Natl Acad Sci U S A | 1984 | https://conductscience.org/library/papers/6608106 | PubMed |
| 6,430,792 | Localization of histaminase to the specific granule of the human neutrophil. | Immunology | 1984 | https://conductscience.org/library/papers/6430792 | PubMed |
| 6,334,697 | Normal human alveolar macrophages obtained by bronchoalveolar lavage have a limited capacity to release interleukin-1. | J Clin Invest | 1984 | https://conductscience.org/library/papers/6334697 | PubMed |
| 6,295,947 | Effects of a phagocytosis-stimulating factor on the phagocytic process of polymorphonuclear neutrophils. | Infect Immun | 1982 | https://conductscience.org/library/papers/6295947 | PubMed |
| 6,277,776 | Identification of a serum-derived promotor of granulocyte granule secretion: study on a patient with chronic pruritus. | Immunology | 1982 | https://conductscience.org/library/papers/6277776 | PubMed |
Genes2
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| GUSB | 2,990 | PubTator's text mining | https://conductscience.org/library/genes/2990 | NCBI Gene |
| LYZ | 4,069 | PubTator's text mining | https://conductscience.org/library/genes/4069 | NCBI Gene |
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- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
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- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
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- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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