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Paper8317554

Age-dependent basal level and induction capacity of copper-zinc and manganese superoxide dismutase and other scavenging enzyme activities in leukocytes from young and elderly adults.

Niwa Y and 4 others. Am J Pathol, 1993. Cited by 49 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Age-dependent basal level and induction capacity of copper-zinc and manganese superoxide dismutase and other scavenging enzyme activities in leukocytes from young and elderly adults. Papers, record 8317554. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/8317554

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Age-dependent basal level and induction capacity of copper-zinc and manganese superoxide dismutase and other scavenging enzyme activities in leukocytes from young and elderly adults.
PubMed
Journal
Am J Pathol
PubMed
Year
1993
PubMed
Publication types
Comparative Study, Journal Article
PubMed
Citations, by iCite
49
iCite
Relative citation ratio, by iCite
1.7
iCite
Revised in PubMed
2018-11-13
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Niwa YY
2Iizawa OO
3Ishimoto KK
4Akamatsu HH
5Kanoh TT

Source PubMed

Topics23

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Free Radical ScavengersMajor topic
LeukocytesMajor topic
Superoxide DismutaseMajor topic
Adolescent
Adult
Aged
Aged, 80 and over
Antineoplastic Agents
Catalase
Enzyme Induction
Female
Glucosephosphate Dehydrogenase
Glutathione Peroxidase
Humans
Immune Sera
Interleukin-1
Lymphocytes
Male
Middle Aged
Neutralization Tests
Neutrophils
Paraquat
Tumor Necrosis Factor-alpha

Source PubMed

References44

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
16,857,269Inhibition of tumor promotion by a biomimetic superoxide dismutase.Science1983https://conductscience.org/library/papers/6857269PubMed
21,938,743Interleukin 1 protects rats against oxygen toxicity.J Appl Physiol (1985)1991https://conductscience.org/library/papers/1938743PubMed
36,625,604Positive correlation between superoxide dismutase and resistance to paraquat toxicity in the green alga Chlorella sorokiniana.Arch Biochem Biophys1983https://conductscience.org/library/papers/6625604PubMed
46,690,675
Enhanced neutrophilic functions in mucocutaneous lymph node syndrome, with special reference to the possible role of increased oxygen intermediate generation in the pathogenesis of coronary thromboarteritis.
J Pediatr1984https://conductscience.org/library/papers/6690675PubMed
56,547,201Assay of superoxide dismutase activity in tumor tissue.Methods Enzymol1984https://conductscience.org/library/papers/6547201PubMed
66,331,179Myocardial alterations due to free-radical generation.Am J Physiol1984https://conductscience.org/library/papers/6331179PubMed
76,500,626Production of a lymphocyte proliferation potentiating factor by purified polymorphonuclear leucocytes from mice and rabbits.Immunology1984https://conductscience.org/library/papers/6500626PubMed
83,022,648Phospholipid base exchange in human leukocyte membranes: quantitation and correlation with other phospholipid biosynthetic pathways.Arch Biochem Biophys1986https://conductscience.org/library/papers/3022648PubMed
93,821,364The ratio of lipidperoxides to superoxide dismutase activity in the skin lesions of patients with severe skin diseases: an accurate prognostic indicator.Life Sci1987https://conductscience.org/library/papers/3821364PubMed
103,339,942The effect of aging on cutaneous lipid peroxide levels and superoxide dismutase activity in guinea pigs and patients with burns.Life Sci1988https://conductscience.org/library/papers/3339942PubMed
113,377,528Experimental burn-induced changes in lipid peroxide levels, and activity of superoxide dismutase and glutathione peroxidase in skin lesions, serum, and liver of mice.Arch Dermatol Res1988https://conductscience.org/library/papers/3377528PubMed
123,263,703Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism.Science1988https://conductscience.org/library/papers/3263703PubMed
133,263,930Induction of mitochondrial manganese superoxide dismutase by interleukin 1.FASEB J1988https://conductscience.org/library/papers/3263930PubMed
143,200,113Follow-up study of lipid peroxides, superoxide dismutase and glutathione peroxidase in the synovial membrane, serum and liver of young and old mice with collagen-induced arthritis.Life Sci1988https://conductscience.org/library/papers/3200113PubMed
152,733,545Neutrophil chemotaxis, phagocytosis and parameters of reactive oxygen species in human aging: cross-sectional and longitudinal studies.Life Sci1989https://conductscience.org/library/papers/2733545PubMed
162,547,324An assay for superoxide dismutase activity in mammalian tissue homogenates.Anal Biochem1989https://conductscience.org/library/papers/2547324PubMed
172,547,375Induction of manganese superoxide dismutase by tumor necrosis factor in human breast cancer MCF-7 cell line and its TNF-resistant variant.Biochem Biophys Res Commun1989https://conductscience.org/library/papers/2547375PubMed
182,475,571Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis.J Exp Med1989https://conductscience.org/library/papers/2475571PubMed
192,383,659Induction of superoxide dismutase in leukocytes by paraquat: correlation with age and possible predictor of longevity.Blood1990https://conductscience.org/library/papers/2383659PubMed
201,965,068Bacterial defenses against oxidative stress.Trends Genet1990https://conductscience.org/library/papers/1965068PubMed

See all 44 references

Cited by13

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 49 citations.

PMIDTitleJournalYearIn PapersSource
38,938,571The global role of G6PD in infection and immunity.Front Immunol2024https://conductscience.org/library/papers/38938571PubMed
36,421,428Resistance Training Modulates Reticulum Endoplasmic Stress, Independent of Oxidative and Inflammatory Responses, in Elderly People.Antioxidants (Basel)2022https://conductscience.org/library/papers/36421428PubMed
28,955,364Identification and Functional Annotation of Genes Differentially Expressed in the Reproductive Tissues of the Olive Tree (Olea europaea L.) through the Generation of Subtractive Libraries.Front Plant Sci2017https://conductscience.org/library/papers/28955364PubMed
28,676,088Parasitological and biochemical studies on cutaneous leishmaniasis in Shara'b District, Taiz, Yemen.Ann Clin Microbiol Antimicrob2017https://conductscience.org/library/papers/28676088PubMed
26,066,302Oxidative stress response and Nrf2 signaling in aging.Free Radic Biol Med2015https://conductscience.org/library/papers/26066302PubMed
20,972,374Age associated oxidative damage in lymphocytes.Oxid Med Cell Longev2010https://conductscience.org/library/papers/20972374PubMed
20,835,307Reactive oxygen metabolites can be used to differentiate malignant and non-malignant pleural efffusions.Ann Thorac Med2010https://conductscience.org/library/papers/20835307PubMed
19,428,455Increased age reduces DAF-16 and SKN-1 signaling and the hormetic response of Caenorhabditis elegans to the xenobiotic juglone.Mech Ageing Dev2009https://conductscience.org/library/papers/19428455PubMed
12,692,182Effect of vitamin C supplements on antioxidant defence and stress proteins in human lymphocytes and skeletal muscle.J Physiol2003https://conductscience.org/library/papers/12692182PubMed
10,718,629Oxidative stress in the human heart is associated with changes in the antioxidative defense as shown after heart transplantation.Mol Cell Biochem2000https://conductscience.org/library/papers/10718629PubMed
9,610,813Immunocytochemical demonstration of the expression and induction of manganese-superoxide dismutase in the adenohypophysis.Histochem J1998https://conductscience.org/library/papers/9610813PubMed
9,512,531Identification of stress-responsive genes in Caenorhabditis elegans using RT-PCR differential display.Nucleic Acids Res1998https://conductscience.org/library/papers/9512531PubMed
8,141,612Long-term follow-up study of changes in lipid peroxide levels and the activity of superoxide dismutase, catalase and glutathione peroxidase in mouse skin after acute and chronic UV irradiation.Arch Dermatol Res1994https://conductscience.org/library/papers/8141612PubMed

Genes6

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
CAT847PubTator's text mininghttps://conductscience.org/library/genes/847NCBI Gene
IL1A3,552PubTator's text mininghttps://conductscience.org/library/genes/3552NCBI Gene
IL1B3,553PubTator's text mininghttps://conductscience.org/library/genes/3553NCBI Gene
SOD16,647PubTator's text mininghttps://conductscience.org/library/genes/6647NCBI Gene
SOD26,648PubTator's text mininghttps://conductscience.org/library/genes/6648NCBI Gene
TNF7,124PubTator's text mininghttps://conductscience.org/library/genes/7124NCBI Gene

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

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  • Comments and corrections
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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