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Paper90061

Stimulation of neutrophil oxygen-dependent metabolism by human leukocytic pyrogen.

Klempner MS and 3 others. J Clin Invest, 1979. Cited by 130 papers, by iCite.

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ConductScience Library. Stimulation of neutrophil oxygen-dependent metabolism by human leukocytic pyrogen. Papers, record 90061. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/90061

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Stimulation of neutrophil oxygen-dependent metabolism by human leukocytic pyrogen.
PubMed
Journal
J Clin Invest
PubMed
Year
1979
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
130
iCite
Relative citation ratio, by iCite
4.13
iCite
Revised in PubMed
2018-11-13
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Klempner MSM S
2Dinarello CAC A
3Henderson WRW R
4Gallin JIJ I

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
NeutrophilsMajor topic
Oxygen ConsumptionMajor topic
PyrogensMajor topic
TuftsinMajor topic
gamma-GlobulinsMajor topic
Adult
Dose-Response Relationship, Drug
Humans
Nitroblue Tetrazolium
Stimulation, Chemical

Source PubMed

References22

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,090,664Enhancement of nitroblue tetrazolium dye reduction by leukocytes exposed to a component of complement in the absence of phagocytosis.J Immunol1975https://conductscience.org/library/papers/1090664PubMed
21,130,423An appraisal of the nitroblue tetrazolium reduction test.Am J Med1975https://conductscience.org/library/papers/1130423PubMed
311,344,574Stimulation of human neutrophil leukocyte aerobic glucose metabolism by purified chemotactic factors.J Clin Invest1974https://conductscience.org/library/papers/11344574PubMed
5163,283Quantitative aspects of the production of superoxide radicals by phagocytizing human granulocytes.J Lab Clin Med1975https://conductscience.org/library/papers/163283PubMed
622,079Human leukocytic pyrogen: purification and development of a radioimmunoassay.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/22079PubMed
74,105,698N.B.T. test in parasitic disease.Lancet1971https://conductscience.org/library/papers/4105698PubMed
84,109,137Nitroblue tetrazolium dye test: a diagnostic aid in tuberculosis.Am Rev Respir Dis1972https://conductscience.org/library/papers/4109137PubMed
94,123,563Positive N.B.T. test in acute viral hepatitis.Lancet1973https://conductscience.org/library/papers/4123563PubMed
104,154,306Reduced nicotinamide adenine dinucleotide and reduced nicotinamide adenine dinucleotide phosphate diaphorase activity in human polymorphonuclear leukocytes.Infect Immun1974https://conductscience.org/library/papers/4154306PubMed
114,175,397Infection and nitroblue-tetrazolium reduction by neutrophils. A diagnostic acid.Lancet1968https://conductscience.org/library/papers/4175397PubMed
124,179,068Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.Scand J Clin Lab Invest Suppl1968https://conductscience.org/library/papers/4179068PubMed
134,346,473Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent.J Clin Invest1973https://conductscience.org/library/papers/4346473PubMed
144,384,563Quantitative nitroblue tetrazolium test in chronic granulomatous disease.N Engl J Med1968https://conductscience.org/library/papers/4384563PubMed
154,400,956Abnormal bactericidal, metabolic, and lysosomal functions of Chediak-Higashi Syndrome leukocytes.J Clin Invest1972https://conductscience.org/library/papers/4400956PubMed
164,590,440Nitroblue tetrazolium test in Hodgkin disease and other malignant lymphomas.Arch Intern Med1974https://conductscience.org/library/papers/4590440PubMed
174,751,761Letter: Nitroblue tetrazolium dye test.Ann Intern Med1973https://conductscience.org/library/papers/4751761PubMed
184,829,934Demonstration and characterization of two distinct human leukocytic pyrogens.J Exp Med1974https://conductscience.org/library/papers/4829934PubMed
194,933,238Spontaneous in vitro reduction of nitroblue tetrazolium by neutrophils of adult patients with bacterial infection.N Engl J Med1971https://conductscience.org/library/papers/4933238PubMed
205,539,787The use and limitations of the nitroblue tetrazolium test as a diagnostic aid.J Pediatr1971https://conductscience.org/library/papers/5539787PubMed
21559,692The production of antibody against human leukocytic pyrogen.J Clin Invest1977https://conductscience.org/library/papers/559692PubMed

See all 22 references

Cited by34

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 130 citations.

PMIDTitleJournalYearIn PapersSource
8,886,999Clinical, hematologic, and immunologic effects of interleukin-10 in humans.J Clin Immunol1996https://conductscience.org/library/papers/8886999PubMed
8,392,494Activities of superoxide dismutases and NADPH oxidase in neutrophils obtained from asthmatic and normal donors.Inflammation1993https://conductscience.org/library/papers/8392494PubMed
8,317,554Age-dependent basal level and induction capacity of copper-zinc and manganese superoxide dismutase and other scavenging enzyme activities in leukocytes from young and elderly adults.Am J Pathol1993https://conductscience.org/library/papers/8317554PubMed
7,439,989Role of the central nervous system in acute-phase responses to leukocytic pyrogen.Infect Immun1980https://conductscience.org/library/papers/7439989PubMed
7,228,389Differential alterations in host peripheral polymorphonuclear leukocyte chemiluminescence during the course of bacterial and viral infections.Infect Immun1980https://conductscience.org/library/papers/7228389PubMed
6,750,226Production of fever and its effects on the host.Klin Wochenschr1982https://conductscience.org/library/papers/6750226PubMed
6,358,043Effect of ibuprofen on fever and metabolic changes induced by continuous infusion of leukocytic pyrogen (interleukin 1) or endotoxin.Infect Immun1983https://conductscience.org/library/papers/6358043PubMed
6,334,697Normal human alveolar macrophages obtained by bronchoalveolar lavage have a limited capacity to release interleukin-1.J Clin Invest1984https://conductscience.org/library/papers/6334697PubMed
6,305,834Effects of leukocyte inhibitory factor (LIF) on human neutrophil function.Inflammation1983https://conductscience.org/library/papers/6305834PubMed
6,295,947Effects of a phagocytosis-stimulating factor on the phagocytic process of polymorphonuclear neutrophils.Infect Immun1982https://conductscience.org/library/papers/6295947PubMed
6,249,851Use of lipophilic probes of membrane potential to assess human neutrophil activation. Abnormality in chronic granulomatous disease.J Clin Invest1980https://conductscience.org/library/papers/6249851PubMed
6,243,141Mechanisms of antibody-dependent cellular cytotoxicity: the use of effector cells from chronic granulomatous disease patients as investigative probes.J Clin Invest1980https://conductscience.org/library/papers/6243141PubMed
6,212,597Human monocyte-derived soluble product(s) has an accessory function in the generation of histamine- and concanavalin A-induced suppressor T cells.J Clin Invest1982https://conductscience.org/library/papers/6212597PubMed
3,543,052Secretory products of macrophages.J Clin Invest1987https://conductscience.org/library/papers/3543052PubMed
3,497,878Recombinant murine interleukin-1 alpha enhancement of nonspecific antibacterial resistance.Infect Immun1987https://conductscience.org/library/papers/3497878PubMed
3,313,662What's happened to catabolin?Rheumatol Int1987https://conductscience.org/library/papers/3313662PubMed
3,279,154Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties.J Exp Med1988https://conductscience.org/library/papers/3279154PubMed
3,263,325Augmentation of host resistance to microbial infections by recombinant human interleukin-1 alpha.Infect Immun1988https://conductscience.org/library/papers/3263325PubMed
3,261,716Provocation of pulmonary vascular endothelial injury in rabbits by human recombinant interleukin-1 beta.Infect Immun1988https://conductscience.org/library/papers/3261716PubMed
3,169,966Effect of recombinant DNA-produced tumor necrosis factor on various parameters of neutrophil function.Inflammation1988https://conductscience.org/library/papers/3169966PubMed

See all 34 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

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Sources 11

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  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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