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Paper · 54337

Antitoxic immunity in experimental cholera: protection, and serum and local antibody responses in rabbits after enteral and parenteral immunization.

Holmgren J and 5 others. Infect Immun, 1975. Cited by 43 papers, by iCite.

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ConductScience Library. Antitoxic immunity in experimental cholera: protection, and serum and local antibody responses in rabbits after enteral and parenteral immunization. Papers, record 54337. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/54337

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Antitoxic immunity in experimental cholera: protection, and serum and local antibody responses in rabbits after enteral and parenteral immunization.
PubMed
Journal
Infect Immun
PubMed
Year
1975
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
43
iCite
Relative citation ratio, by iCite
1.51
iCite
Revised in PubMed
2021-05-26
PubMed

Authors6

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Holmgren JJ
2Svennerholm AMA M
3Ouchterlony OO
4Anderson AA
5Walletström GG
6Westerberg-Berndtsson UU

Source PubMed

Topics19

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antibody FormationMajor topic
AntitoxinsMajor topic
CholeraMajor topic
ImmunityMajor topic
ImmunizationMajor topic
Administration, Oral
Animals
Antigens, Bacterial
Epitopes
Immunization, Secondary
Immunoglobulin A
Immunoglobulin G
Immunoglobulin M
Injections, Intravenous
Injections, Subcutaneous
Intestinal Mucosa
Rabbits
Toxins, Biological
Vibrio cholerae

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References25

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
1803,547Oligomeric structure of cholera toxin: characteristics of the H and L subunits.J Gen Microbiol1975https://conductscience.org/library/papers/803547PubMed
216,558,049Immunochemical Studies of Two Cholera Toxin-Containing Standard Culture Filtrate Preparations of Vibrio cholerae.Infect Immun1971https://conductscience.org/library/papers/16558049PubMed
34,202,959Enzyme-linked immunosorbent assays for cholera serology.Infect Immun1973https://conductscience.org/library/papers/4202959PubMed
44,205,946Development of a purified cholera toxoid. II. Preparation of a stable, antigenic toxoid by reaction of purified toxin with glutaraldehyde.Infect Immun1974https://conductscience.org/library/papers/4205946PubMed
54,324,714Vibrio cholerae enterotoxin and its mode of action.Bacteriol Rev1971https://conductscience.org/library/papers/4324714PubMed
64,361,243Interaction of cholera toxin and toxin derivatives with lymphocytes. I. Binding properties and interference with lectin-induced cellular stimulation.J Exp Med1974https://conductscience.org/library/papers/4361243PubMed
74,413,777Immunity to experimental cholera. I. Protective effect of humoral IgG antitoxin demonstrated by passive immunization.J Immunol1974https://conductscience.org/library/papers/4413777PubMed
84,472,031Chemical modification of cholera toxin for characterization of antigenic, receptor-binding and toxic sites.FEBS Lett1974https://conductscience.org/library/papers/4472031PubMed
94,509,186Experimental studies on cholera immunization. 1. The response of neutralizing and vibriocidal antibodies in rabbits after immunization with culture filtrate material from V. cholerae.Acta Pathol Microbiol Scand B Microbiol Immunol1972https://conductscience.org/library/papers/4509186PubMed
104,562,844Stimulation of jejunal secretion by a crude Escherichia coli enterotixin.Gastroenterology1972https://conductscience.org/library/papers/4562844PubMed

Cited by24

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 43 citations.

PMIDTitleJournalYearIn PapersSource
24,983,989Safety and immunogenicity of a live oral recombinant cholera vaccine VA1.4: a randomized, placebo controlled trial in healthy adults in a cholera endemic area in Kolkata, India.PLoS One2014https://conductscience.org/library/papers/24983989PubMed
23,468,950Immunization with cholera toxin B subunit induces high-level protection in the suckling mouse model of cholera.PLoS One2013https://conductscience.org/library/papers/23468950PubMed
17,261,601Safety and immunogenicity of an enterotoxigenic Escherichia coli vaccine patch containing heat-labile toxin: use of skin pretreatment to disrupt the stratum corneum.Infect Immun2007https://conductscience.org/library/papers/17261601PubMed
10,024,549Transcutaneous immunization with bacterial ADP-ribosylating exotoxins as antigens and adjuvants.Infect Immun1999https://conductscience.org/library/papers/10024549PubMed
9,525,687Induction of mucosal B-cell memory by intramuscular inoculation of mice with rotavirus.J Virol1998https://conductscience.org/library/papers/9525687PubMed
9,276,729
Localization of a domain in the FimH adhesin of Escherichia coli type 1 fimbriae capable of receptor recognition and use of a domain-specific antibody to confer protection against experimental urinary tract infection.
J Clin Invest1997https://conductscience.org/library/papers/9276729PubMed
7,439,983Improved protection against cholera in adult rabbits with a combined flagellar-toxoid vaccine.Infect Immun1980https://conductscience.org/library/papers/7439983PubMed
7,011,994Immune response of the ileum to invasive Escherichia coli diarrheal disease in rabbits.Infect Immun1981https://conductscience.org/library/papers/7011994PubMed
7,011,992Respective contributions to protection of primary and booster immunization with Escherichia coli heat-labile enterotoxin in rats.Infect Immun1981https://conductscience.org/library/papers/7011992PubMed
7,011,990Protective effect of immunization of rats with holotoxin or B subunit of Escherichia coli heat-labile enterotoxin.Infect Immun1981https://conductscience.org/library/papers/7011990PubMed

1 to 10 of 24

See all 24 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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