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Paper · 565310

Effect of secretin on basal- and glucose-stimulated insulin secretion in man.

Fahrenkrug J and 2 others. Diabetologia, 1978. Cited by 39 papers, by iCite.

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ConductScience Library. Effect of secretin on basal- and glucose-stimulated insulin secretion in man. Papers, record 565310. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/565310

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Effect of secretin on basal- and glucose-stimulated insulin secretion in man.
PubMed
Journal
Diabetologia
PubMed
Year
1978
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
39
iCite
Relative citation ratio, by iCite
1.3
iCite
Revised in PubMed
2026-10-10
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Fahrenkrug JJ
2Schaffalitzky de Muckadell OBO B
3Kühl CC

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
GlucoseMajor topic
InsulinMajor topic
SecretinMajor topic
Adult
Animals
Antigens
Dose-Response Relationship, Drug
Female
Humans
Injections, Intravenous
Insulin Secretion
Male
Stimulation, Chemical
Swine

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References29

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
15,116,204Secretion of glucagon from the isolated, perfused canine pancreas.J Clin Invest1971https://conductscience.org/library/papers/5116204PubMed
2775,874Secretin-induced insulin response. II. Dose-response relation.Acta Endocrinol (Copenh)1976https://conductscience.org/library/papers/775874PubMed
34,169,787Failure of endogenous stimulation of secretin and pancreozymin release to influence serum-insulin.Lancet1968https://conductscience.org/library/papers/4169787PubMed
45,698,974[Stimulation of insulin secretion in diabetics using secretin].Dtsch Med Wochenschr1968https://conductscience.org/library/papers/5698974PubMed
54,902,719[Blood sugar and plasma insulin response to stimulation of endogenous secretin release].Diabetologia1969https://conductscience.org/library/papers/4902719PubMed
65,796,357The gastrointestinal stimulus to insulin release. I. Secretin.J Clin Invest1969https://conductscience.org/library/papers/5796357PubMed
74,815,082Effects of intraduodenal administration of HCl and glucose on circulating immunoreactive secretin and insulin concentrations.J Clin Invest1974https://conductscience.org/library/papers/4815082PubMed
88,364Plasma insulin concentration during physiological variations in immunoreactive plasma secretin.Horm Metab Res1976https://conductscience.org/library/papers/8364PubMed
917,153Plasma secretin concentration in anaesthetized pigs after intraduodenal glucose, fat, aminoacids, or meals with various pH.Scand J Gastroenterol1977https://conductscience.org/library/papers/17153PubMed
10940,982Production and evaluation of antibodies for radioimmunoassay of secretin.Scand J Clin Lab Invest1976https://conductscience.org/library/papers/940982PubMed

Cited by13

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 39 citations.

PMIDTitleJournalYearIn PapersSource
34,671,320Pleiotropic Effects of Secretin: A Potential Drug Candidate in the Treatment of Obesity?Front Endocrinol (Lausanne)2021https://conductscience.org/library/papers/34671320PubMed
33,782,700The Role of Incretins on Insulin Function and Glucose Homeostasis.Endocrinology2021https://conductscience.org/library/papers/33782700PubMed
32,217,097Rational development of a high-affinity secretin receptor antagonist.Biochem Pharmacol2020https://conductscience.org/library/papers/32217097PubMed
31,080,438From the Incretin Concept and the Discovery of GLP-1 to Today's Diabetes Therapy.Front Endocrinol (Lausanne)2019https://conductscience.org/library/papers/31080438PubMed
30,061,863The Origin and Understanding of the Incretin Concept.Front Endocrinol (Lausanne)2018https://conductscience.org/library/papers/30061863PubMed
21,525,464Loss of incretin effect is a specific, important, and early characteristic of type 2 diabetes.Diabetes Care2011https://conductscience.org/library/papers/21525464PubMed
20,503,484Secretin: Should we revisit its metabolic outcomes?J Endocrinol Invest2010https://conductscience.org/library/papers/20503484PubMed
7,009,286Effects of vasoactive intestinal polypeptide (VIP), secretin and gastrin on insulin secretion in the mouse.Diabetologia1981https://conductscience.org/library/papers/7009286PubMed
6,350,081Preservation of incretin activity after removal of gastric inhibitory polypeptide (GIP) from rat gut extracts by immunoadsorption.Diabetologia1983https://conductscience.org/library/papers/6350081PubMed
3,519,339Effects of endogenous and exogenous secretin on plasma pancreatic polypeptide concentrations in dogs.Diabetologia1986https://conductscience.org/library/papers/3519339PubMed

1 to 10 of 13

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Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
INS3,630PubTator's text mininghttps://conductscience.org/library/genes/3630NCBI Gene
SCT6,343PubTator's text mininghttps://conductscience.org/library/genes/6343NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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